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NEFERTITI SIGNED

NEFERTITI: A Novel Eco-Friendly, dually Efficient and Resistance-free Treatment of vaginITIs

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

NEFERTITI project word cloud

Explore the words cloud of the NEFERTITI project. It provides you a very rough idea of what is the project "NEFERTITI" about.

plan antimicrobials benign glucono free socioeconomic supports heavy antifungals substance gedea gda candida trial validation fungus global business biofilm causing antibiotics gap tablet threats market vcc treatment clinical performed infections resistance preclinical prolonged million lies keep discharge biggest date efficacy bay treat phyph close incidence drug burden caused vaginosis yeast bv lactone bacterial delta gardnerella unmet discomfort commercialization relapse causes preventative bacteria reduce life candidiasis mechanism limited road instrument antibiotic 450 form vaginal restores curative switches adversely commercialisation least treatments disrupts recurrent natural removed overconsumption eliminate prepare contains ph rate guide sme normally health misdiagnosis globally vulvovaginal healthy quality

Project "NEFERTITI" data sheet

The following table provides information about the project.

Coordinator	GEDEA BIOTECH AB Organization address address: MEDICON VILLAGE SCHEELEVAGEN 2 city: LUND postcode: 223 81 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Sweden [SE]
Project website	http://gedeabiotech.com/
Total cost	71˙429 €
EC max contribution	50˙000 € (70%)
Programme	1. H2020-EU.3. (PRIORITY 'Societal challenges) 2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs) 3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
Code Call	H2020-SMEInst-2018-2020-1
Funding Scheme	SME-1
Starting year	2018
Duration (year-month-day)	from 2018-12-01 to 2019-05-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	GEDEA BIOTECH AB GEDEA BIOTECH AB Organization address address: MEDICON VILLAGE SCHEELEVAGEN 2 city: LUND postcode: 223 81 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SE (LUND)	coordinator	50˙000.00

Map

Project objective

This project will develop a business plan to guide clinical validation and commercialization of pHyph, a novel treatment targeting vaginal yeast and bacterial infections. Bacterial vaginosis (BV) and vulvovaginal candidiasis (VCC) are common vaginal infections caused by bacteria (often Gardnerella) or yeast (a fungus) called Candida. 450 million globally experience at least 4 vaginal bacteria or Candida infections each year. It causes significant discomfort, adversely affects quality of life and is associated with heavy socioeconomic burden. To date, all treatments are limited to antifungals and antibiotics that show low efficacy and high relapse rate. With prolonged usage, misdiagnosis, and overconsumption, there is a high incidence of drug resistance, which the WHO considered one of the biggest threats to global health. Gedea has developed a vaginal tablet that contains the natural substance Glucono-δ-lactone (GDA), which switches Candida towards a benign yeast form, restores vaginal pH and disrupts the Candida and bacteria biofilm without causing treatment resistance. The yeast is removed through vaginal discharge. Since this is an antibiotic-free treatment, healthy bacteria that normally keep Candida at bay are also not removed and therefore a low relapse rate is expected with the use of pHyph. The product’s key feature lies in its ability to treat both yeast and bacterial infections and its use as both a preventative and curative treatment. These features are unmet by any other product on the market. Preclinical research performed to date strongly supports pHyph’s novel mechanism to treat vaginal infections, reduce recurrent infections and eliminate the need for antibiotics/antimicrobials. The proposed project will further prepare pHyph for a clinical trial. SME Instrument funding will allow Gedea to close the gap on the road towards commercialisation.

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The information about "NEFERTITI" are provided by the European Opendata Portal: CORDIS opendata.