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REFRACT SIGNED

Repeat protein Function Refinement, Annotation and Classification of Topologies

Total Cost €

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EC-Contrib. €

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Partnership

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Project "REFRACT" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITA DEGLI STUDI DI PADOVA 

Organization address
address: VIA 8 FEBBRAIO 2
city: PADOVA
postcode: 35122
website: www.unipd.it

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Total cost 2˙392˙000 €
 EC max contribution 2˙226˙400 € (93%)
 Programme 1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
 Code Call H2020-MSCA-RISE-2018
 Funding Scheme MSCA-RISE
 Starting year 2019
 Duration (year-month-day) from 2019-01-01   to  2022-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITA DEGLI STUDI DI PADOVA IT (PADOVA) coordinator 556˙600.00
2    AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS ES (MADRID) participant 358˙800.00
3    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR (PARIS) participant 358˙800.00
4    JOHANNES GUTENBERG-UNIVERSITAT MAINZ DE (MAINZ) participant 266˙800.00
5    ZURCHER HOCHSCHULE FUR ANGEWANDTE WISSENSCHAFTEN CH (WINTERTHUR) participant 262˙200.00
6    EUROPEAN MOLECULAR BIOLOGY LABORATORY DE (HEIDELBERG) participant 225˙400.00
7    STOCKHOLMS UNIVERSITET SE (STOCKHOLM) participant 197˙800.00
8    CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA CU (LA HABANA) partner 0.00
9    CENTRO DE INVESTIGATION CIENTIFICACAUCASECO LIMITADA CO (CALI) partner 0.00
10    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE CL (SANTIAGO) partner 0.00
11    PONTIFICIA UNIVERSIDAD CATOLICA DEL PERU PE (LIMA) partner 0.00
12    UNIVERSIDAD DEL CAUCA CO (POPAYAN) partner 0.00
13    UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO MX (MEXICO DISTRITO FEDERAL) partner 0.00
14    UNIVERSIDAD NACIONAL DE LA PLATA AR (LA PLATA) partner 0.00
15    UNIVERSIDAD NACIONAL DE QUILMES AR (BERNAL) partner 0.00
16    UNIVERSIDAD PERUANA CAYETANO HEREDIA PE (LIMA) partner 0.00

Map

 Project objective

The REFRACT proposal answers the RISE call, aiming at the promotion of an international and interdisciplinary collaboration on tandem repeat proteins (TRPs) through the sharing of knowledge and expertise between partners via staff exchanges. REFRACT is an international consortium aiming to extend our knowledge on the mechanism of TRP function and evolution, establishing a common classification and best practices. Starting from available state of the art computational tools and databases, which have been mostly developed by REFRACT participants, it aims drive a new level of TRP characterization leveraging the complementary expertise of 7 EU MS and 9 TC institutions in Latin America, with the latter providing useful complementary expertises. This aim will be achieved by the following steps: Benchmarking different existing methods and defining their use-cases; Coordinating the necessary next steps to analyze TRP roles in biological pathways and organism evolution; Providing a detailed description of their mechanism of function, related to their structural properties, that can be of great importance in TRP-related medical research and biotechnological applications; Building a unified and commonly accepted TRP classification from sequence and structure as well as characterizing the relationship between the two. The REFRACT implementation will take advantage of the different expertises, supporting them by a combination of research-centered, training and dissemination activities. The secondment program is designed so that all the participating institutions will be actively involved not only in the production of scientific outcomes, but also be empowered with the responsibility of planning, monitoring and discussing project advancement. The broadest possible dissemination of the results will be achieved through dedicated activities, the propagation of results into ELIXIR core data resources (InterPro, and consequently UniProt) as well as possible industrial exploitation.

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