Explore the words cloud of the MNSWLGM project. It provides you a very rough idea of what is the project "MNSWLGM" about.
The following table provides information about the project.
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
|Coordinator Country||Switzerland [CH]|
|Total cost||187˙419 €|
|EC max contribution||187˙419 € (100%)|
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
|Duration (year-month-day)||from 2019-08-01 to 2021-07-31|
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|1||EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH||CH (ZUERICH)||coordinator||187˙419.00|
Extracellular vesicles (EVs) describe distinct populations of small (30-200 nm) and large (500 nm-2 μm) microvesicles actively or passively secreted by cells. Whilst, they are recognized as promising biomarkers for diseases diagnosis, prognosis and therapy, their purification, selective enrichment, and characterization remains immensely challenging. The goal of the current proposal is to develop an optofluidic platform able to manipulate and characterize single EVs and facilitate their efficient purification and quantitation from biological samples. The optofluidic platform will incorporate a dynamically reconfigurable optical lattice (constructed from a liquid gradient refractive index - L-GRIN microlens) for separation followed by a viscoelastic focusing module for single EV imaging. The strength of the interaction between a nanoparticle and the optical lattice will depend on the optical polarizability of the particle, thus providing a size selection criterion to allow identification and isolation. Put simply, we aim to develop a size-selective optofluidic platform integrated for non-invasive EVs sorting and fractionation that can be applied to a wide range of biological matrices and addresses the most challenging technological bottleneck in EVs research.
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The information about "MNSWLGM" are provided by the European Opendata Portal: CORDIS opendata.