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VOGAS SIGNED

Screening of Gastric Cancer via Breath volatile organic compounds by Hybrid Sensing Approach

Total Cost €

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EC-Contrib. €

0

Partnership

0

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VOGAS project word cloud

Explore the words cloud of the VOGAS project. It provides you a very rough idea of what is the project "VOGAS" about.

spectrometry sensors cured confounding intestinal schemes compounds invasive headspace coupled breath panels brazil gc acquired members human parallel american dimensional exhaled detecting mass data disease collaborations chile ms gastric spectroscopic optimized tool competences nose orthogonal flora voc metaplasia ukraine analytical electronic stage infrared oxide mechanisms vocs geographical precancerous infection cancer bacterial diagnosed organic latin enrolled good validated composition nanoparticles prototypes combine patients clinical atrophy screening mid volatile expertise latvia techniques dysplasia burden chromatography origin compact obtaining building pylori chances gold lack eastern lesions america lines cell utilizing device concentration colombia first components international countries individuals vital gas previously portable metal tissue analyser

Project "VOGAS" data sheet

The following table provides information about the project.

Coordinator	TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY Organization address address: SENATE BUILDING TECHNION CITY city: HAIFA postcode: 32000 website: www.technion.ac.il contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Israel [IL]
Total cost	3˙781˙179 €
EC max contribution	3˙781˙179 € (100%)
Programme	1. H2020-EU.3.1.3. (Treating and managing disease)
Code Call	H2020-SC1-2018-Single-Stage-RTD
Funding Scheme	RIA
Starting year	2019
Duration (year-month-day)	from 2019-01-01 to 2021-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY Organization address address: SENATE BUILDING TECHNION CITY city: HAIFA postcode: 32000 website: www.technion.ac.il contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IL (HAIFA)	coordinator	650˙363.00
2	LATVIJAS UNIVERSITATE LATVIJAS UNIVERSITATE Organization address address: RAINIS BOULEVARD 19 city: RIGA postcode: 1586 website: http://www.lu.lv contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	LV (RIGA)	participant	510˙000.00
3	UNIVERSITAET INNSBRUCK UNIVERSITAET INNSBRUCK Organization address address: INNRAIN 52 city: INNSBRUCK postcode: 6020 website: http://www.uibk.ac.at contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (INNSBRUCK)	participant	395˙535.00
4	UNIVERSITAET ULM UNIVERSITAET ULM Organization address address: HELMHOLTZSTRASSE 16 city: ULM postcode: 89081 website: www.uni-ulm.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (ULM)	participant	385˙000.00
5	JLM INNOVATION GMBH JLM INNOVATION GMBH Organization address address: BEETHOVENWEG 41 city: TUEBINGEN postcode: 72076 website: www.jlm-innovation.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (TUEBINGEN)	participant	375˙000.00
6	Teknologian tutkimuskeskus VTT Oy Teknologian tutkimuskeskus VTT Oy Organization address address: VUORIMIEHENTIE 3 city: Espoo postcode: 2150 website: www.vtt.fi contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FI (Espoo)	participant	358˙875.00
7	UPPSALA UNIVERSITET UPPSALA UNIVERSITET Organization address address: VON KRAEMERS ALLE 4 city: UPPSALA postcode: 751 05 website: www.uu.se contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SE (UPPSALA)	participant	253˙727.00
8	UNIVERSIDAD DE PAMPLONA UNIVERSIDAD DE PAMPLONA Organization address address: CIUDAD UNIVERSITARIA KM 1 VIA BUCARAMANGA city: PAMPLONA postcode: n.a. website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CO (PAMPLONA)	participant	250˙625.00
9	NATIONAL CANCER INSTITUTE NATIONAL CANCER INSTITUTE Organization address address: 33/43 LOMONOSOVA STREET city: KIYV postcode: 3022 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UA (KIYV)	participant	210˙000.00
10	HOSPITAL UNIVERSITARIO SAN IGNACIO HOSPITAL UNIVERSITARIO SAN IGNACIO Organization address address: CARRERA 7 NO 40-62, PISO2 HOSPITAL UNIVERSITARIO SAN IGNACIO city: BOGOTA postcode: 110231 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CO (BOGOTA)	participant	209˙984.00
11	PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE Organization address address: AVENIDA LIBERTADOR BERNARDO O'HIGGINS 340 city: SANTIAGO postcode: 8331150 website: www.uc.cl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CL (SANTIAGO)	participant	182˙068.00
12	FUNDACAO ANTONIO PRUDENTE FUNDACAO ANTONIO PRUDENTE Organization address address: RUA PROF ANTONIO PRUDENTE 211 city: SAO PAULO postcode: 1509010 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BR (SAO PAULO)	participant	0.00

Map

Project objective

Gastric cancer has good chances to be cured if diagnosed at an early stage; currently, there is lack of a reliable non-invasive screening tool. Eastern Europe and Latin America are among the geographical areas with high burden of the disease.

This project is aiming at developing a non-invasive gastric cancer screening tool by detecting characteristic panels of volatile organic compounds (VOCs). The mechanisms of VOC origin and their composition in gastric cancer patients will be addressed via headspace analysis of cancer tissue, cell-lines, and bacterial flora; VOCs identified during this analysis will be compared to the compounds present in human breath, both via gas chromatography coupled to mass spectrometry (GC-MS).

Based on this data, a new type of breath analyser will be developed and validated building upon previously acquired expertise of the consortium members. Specifically, the exhaled breath analyser will combine electronic nose concepts utilizing gold nanoparticles and metal oxide sensors with orthogonal mid-infrared spectroscopic techniques for obtaining multi-dimensional analytical data sets; furthermore, compact pre-concentration schemes will be evaluated. All components will be integrated into several prototypes of portable and optimized devices.

The clinical studies will be conducted in parallel in European (Latvia, Ukraine) and Latin American (Colombia, Brazil, Chile) countries with high disease burden. Patients with gastric cancer and individuals with and without precancerous lesions (dysplasia, atrophy, intestinal metaplasia) will be enrolled. The role of confounding factors including H.pylori infection will be addressed.

As the main result, we expect to provide the first reliable non-invasive gastric cancer screening device based on exhaled breath analysis concepts for future large-scale implementation. The development of according research competences and international collaborations therefore is the most vital component of this project.

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The information about "VOGAS" are provided by the European Opendata Portal: CORDIS opendata.

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