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Capsulight

The first ingestible capsule for eradicating Helicobacter pylori infection through photodynamic therapy

Total Cost €

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EC-Contrib. €

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Partnership

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 Capsulight project word cloud

Explore the words cloud of the Capsulight project. It provides you a very rough idea of what is the project "Capsulight" about.

antibiotic    usually    scuola    microbiology    off    pylori    world    ingestible    economic    therapy    cycles    advantages    probiomedica    gastroenterology    presented    once    infected    helicobacter    sant    power    photodynamic    pharmacological    therapies    biopsies    posology    centers    clinical    gastric    hospitalization    diagnostic    unparalleled    patented    pump    diagnosed    assumption    medicine    safety    stomach    university    agent    inhibitor    possibility    florence    mark    resistance    biopsy    superiore    countries    eradicate    population    despite    mass    ce    treatment    rate    capsules    intragastric    specialized    market    savings    endoscopic    carcinogen    infection    drug    attributable    bacterium    killing    efficacy    device    90    undergo    reaching    50    tests    healthcare    robotics    spin    drugs    cured    miniaturization    97    unfortunately    photobiology    first    national    proton    cancers    70    capsulight    eradicated    reducing    optimize    30    preliminary    vitro    capsule    anna    mix    secondary    showed    validation    light   

Project "Capsulight" data sheet

The following table provides information about the project.

Coordinator
PROBIOMEDICA SRL 

Organization address
address: VIA DI BELLOSGUARDO 2 ROSSO
city: FIRENZE
postcode: 50124
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Project website https://www.probiomedica.it
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2019
 Duration (year-month-day) from 2019-02-01   to  2019-07-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    PROBIOMEDICA SRL IT (FIRENZE) coordinator 50˙000.00

Map

 Project objective

Helicobacter pylori (H. pylori) is a bacterium of the stomach which affects on average 50% of the world population, reaching up to 70% in some European Countries. Once it is diagnosed, it has to be eradicated, since it is a carcinogen agent and around 90% of all gastric cancers can be attributable to its infection. The only available treatment is a pharmacological therapy based on the assumption of proton-pump inhibitor and a mix of 2-3 antibiotic drugs. Unfortunately, due to increasing antibiotic resistance, up to 30% of the affected population cannot be cured, despite several cycles of antibiotic therapy and usually endoscopic biopsy to determine antibiotic-resistance. Probiomedica is a spin-off of the University of Florence and Scuola Superiore Sant’Anna specialized in photobiology and robotics applied to medicine, which has developed and patented CapsuLight, the first ingestible capsule able to eradicate H. Pylori infection through intragastric photodynamic therapy, that is through the power of light. The device is based on the established technology and safety of endoscopic capsules for diagnostic use, and our preliminary in vitro tests showed 97% efficacy in killing the bacterium. The advantages for infected population are unparalleled: the possibility to eradicate the bacterium for those who cannot be cured due to antibiotic resistance (our first target market); the higher efficacy rate, no side effects due to antibiotic cycles, and easy posology for all the infected population (secondary market). CapsuLight will also provide high economic savings to National Healthcare Systems, by reducing drug therapies cycles and endoscopic biopsies and related costs for hospitalization. Probiomedica has already presented the product to several gastroenterology and microbiology centers and will optimize the capsule design for further miniaturization and mass production, and to undergo the necessary clinical validation for getting the CE mark during the Phase 2 project.

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The information about "CAPSULIGHT" are provided by the European Opendata Portal: CORDIS opendata.

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