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Opendata, web and dolomites

HAIKU

A breakthrough alternative to antibiotics for preventing and curing infectious diseases at Intensive Care Units

Total Cost €

EC-Contrib. €

Partnership

Views

Outcomes and
results

HAIKU project word cloud

Explore the words cloud of the HAIKU project. It provides you a very rough idea of what is the project "HAIKU" about.

mission admitted days worldwide 275 mortality multiple stays gt 01 care patients group removing beds units preventive protection consist drug icu antibiotics develops reduce inhibitory 1000 molecule 56 trials market licensed removal bacteria de resistance 2026 13 risk remab 150 million generating 21 addressable line 15 royalties complete natural biotech price ebitda ra 6 irr therapy created 800 23 prolonged 10 jobs discount cumulative antimicrobial freeing class social infectivity finalise icus curative morbidity portfolio therapeutics competitors therapies lives treatment newly preventing 14 critical public healthcare clinical diseases rate resistant intensive acquired infections curing medicines first hospital total amr company 240 private companies infectious pharma families net negative share antibodies sales ph2 gram risked benefit

Project "HAIKU" data sheet

The following table provides information about the project.

Coordinator	REMAB THERAPEUTICS SL Organization address address: C FEIXA LLARGA SN EDIFICIO BIOPOL OFFICE 3 city: HOSPITALET DE LLOBREGAT postcode: 8907 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Spain [ES]
Project website	https://remabtx.com/
Total cost	71˙429 €
EC max contribution	50˙000 € (70%)
Programme	1. H2020-EU.3. (PRIORITY 'Societal challenges) 2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs) 3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
Code Call	H2020-SMEInst-2018-2020-1
Funding Scheme	SME-1
Starting year	2018
Duration (year-month-day)	from 2018-12-01 to 2019-05-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	REMAB THERAPEUTICS SL REMAB THERAPEUTICS SL Organization address address: C FEIXA LLARGA SN EDIFICIO BIOPOL OFFICE 3 city: HOSPITALET DE LLOBREGAT postcode: 8907 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (HOSPITALET DE LLOBREGAT)	coordinator	50˙000.00

Map

Project objective

Hospital-acquired infections are a major cause of morbidity, mortality and costs in Intensive care units (ICUs) worldwide. The most critical infectious group consist of Gram-negative bacteria that are resistant to multiple antibiotics.

We have developed RA-01, a novel drug product and a first line therapy for preventing and curing infectious diseases at ICUs based on the removal of inhibitory antibodies, which are used by bacteria to facilitate their infectivity. This new drug allows an immediate protection to patients admitted to ICU without generating antimicrobial resistance (AMR).

RA-01 will reduce public/private healthcare systems costs and improve a social benefit by freeing up hospital beds: €9,150 reduction in treatment costs, 7 days less at ICU and €15 k reduction in ICU costs.

Currently, our competitors are focused on new antibiotics and antibodies, so there are no other companies working in the removing of specific antibodies as a preventive and curative method for infectious diseases. The total potential market is estimated to be >13 million patients/year. From this market, will be target ICU patients at risk for prolonged stays: >4 million patients.

RemAb Therapeutics is a biotech company that develops a novel class of medicines by removing natural specific antibodies. Our mission is to advance our portfolio of therapies to clinical trials and improve the lives of patients and families affected by infectious diseases. Our drug molecule will be developed and de-risked through clinical trials-Ph2 and then licensed to pharma companies, to finalise their development and bring them to the market

By 2026 we expect to reach: a) 14% royalties’ rate on net sales with a RA-01 price to healthcare systems of €800-1000 (complete treatment); b) Total addressable market growing up to about €275 m; c) Net present value of €21.4 m (10% discount rate) and an IRR of 56%; d) Cumulative EBITDA over €23 m; e) 6% market share (240,000 patients); f) 15 newly created jobs.

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The information about "HAIKU" are provided by the European Opendata Portal: CORDIS opendata.