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HAIKU

A breakthrough alternative to antibiotics for preventing and curing infectious diseases at Intensive Care Units

Total Cost €

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EC-Contrib. €

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Partnership

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 HAIKU project word cloud

Explore the words cloud of the HAIKU project. It provides you a very rough idea of what is the project "HAIKU" about.

care    removal    discount    antimicrobial    ra    families    infectivity    million    net    admitted    negative    mortality    created    800    drug    acquired    irr    trials    medicines    icus    healthcare    company    share    removing    reduce    morbidity    benefit    intensive    mission    2026    23    275    jobs    licensed    private    1000    resistance    complete    pharma    preventing    beds    10    curing    units    ebitda       patients    protection    14    companies    cumulative    amr    biotech    13    01    antibiotics    molecule    risked    group    sales    inhibitory    first    natural    finalise    antibodies    treatment    stays    price    icu    21    gram    hospital    150    risk    lives    therapy    56    prolonged    public    class    social    de    freeing    infectious    consist    generating    newly    preventive    critical    royalties    15    therapeutics    competitors    days    ph2    resistant    addressable    240    clinical    portfolio    diseases    therapies    total    multiple    remab    develops    market    bacteria    gt    line    infections    worldwide    curative    rate   

Project "HAIKU" data sheet

The following table provides information about the project.

Coordinator
REMAB THERAPEUTICS SL 

Organization address
address: C FEIXA LLARGA SN EDIFICIO BIOPOL OFFICE 3
city: HOSPITALET DE LLOBREGAT
postcode: 8907
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Project website https://remabtx.com/
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2018
 Duration (year-month-day) from 2018-12-01   to  2019-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    REMAB THERAPEUTICS SL ES (HOSPITALET DE LLOBREGAT) coordinator 50˙000.00

Map

Leaflet | Map data © OpenStreetMap contributors, CC-BY-SA, Imagery © Mapbox

 Project objective

Hospital-acquired infections are a major cause of morbidity, mortality and costs in Intensive care units (ICUs) worldwide. The most critical infectious group consist of Gram-negative bacteria that are resistant to multiple antibiotics.

We have developed RA-01, a novel drug product and a first line therapy for preventing and curing infectious diseases at ICUs based on the removal of inhibitory antibodies, which are used by bacteria to facilitate their infectivity. This new drug allows an immediate protection to patients admitted to ICU without generating antimicrobial resistance (AMR).

RA-01 will reduce public/private healthcare systems costs and improve a social benefit by freeing up hospital beds: €9,150 reduction in treatment costs, 7 days less at ICU and €15 k reduction in ICU costs.

Currently, our competitors are focused on new antibiotics and antibodies, so there are no other companies working in the removing of specific antibodies as a preventive and curative method for infectious diseases. The total potential market is estimated to be >13 million patients/year. From this market, will be target ICU patients at risk for prolonged stays: >4 million patients.

RemAb Therapeutics is a biotech company that develops a novel class of medicines by removing natural specific antibodies. Our mission is to advance our portfolio of therapies to clinical trials and improve the lives of patients and families affected by infectious diseases. Our drug molecule will be developed and de-risked through clinical trials-Ph2 and then licensed to pharma companies, to finalise their development and bring them to the market

By 2026 we expect to reach: a) 14% royalties’ rate on net sales with a RA-01 price to healthcare systems of €800-1000 (complete treatment); b) Total addressable market growing up to about €275 m; c) Net present value of €21.4 m (10% discount rate) and an IRR of 56%; d) Cumulative EBITDA over €23 m; e) 6% market share (240,000 patients); f) 15 newly created jobs.

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The information about "HAIKU" are provided by the European Opendata Portal: CORDIS opendata.

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