Opendata, web and dolomites
CatchGel SIGNED
Catch Bond Cross-linked Hydrogels
Total Cost €
0EC-Contrib. €
0Partnership
0Views
0CatchGel project word cloud
Explore the words cloud of the CatchGel project. It provides you a very rough idea of what is the project "CatchGel" about.
complexes
bond
force
bonds
ing
peristaltic
area
networks
mimicking
nature
smooth
motion
functionalise
bacterial
science
transplant
mechanically
fundamental
muscle
revolutionise
constructed
relatively
tensile
amino
macroscale
surface
ligand
environmental
material
disease
scaled
adhesive
receptor
acid
drive
observation
materials
organ
synthetic
sequence
dynamic
modified
bacteria
bio
model
whilst
move
catch
workings
roll
biology
adaptable
polymer
chains
responsible
push
stress
isolating
contrast
exploring
truly
fashion
designs
slip
remarkable
display
reminiscent
maximum
interdisciplinary
inclusion
intrinsic
reaching
biomimetic
exhibit
action
cells
molecular
insights
decreases
boundaries
gained
reverts
thoughout
enormous
Project "CatchGel" data sheet
The following table provides information about the project.
| Coordinator |
UNIVERSITAT BASEL
Organization address contact info |
| Coordinator Country | Switzerland [CH] |
| Total cost | 304˙724 € |
| EC max contribution | 304˙724 € (100%) |
| Programme |
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility) |
| Code Call | H2020-MSCA-IF-2018 |
| Funding Scheme | MSCA-IF-EF-CAR |
| Starting year | 2020 |
| Duration (year-month-day) | from 2020-01-01 to 2022-12-31 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | UNIVERSITAT BASEL | CH (BASEL) | coordinator | 304˙724.00 |
Map
Project objective
Catch bonds are one of Nature’s truly remarkable designs, which exhibit increased adhesive force as tensile force is applied, in contrast to traditional slip bonds whose adhesive force decreases under similar conditions. On reaching a maximum applied force, the catch bond then reverts to traditional slip bond behaviour resulting in a catch-and-roll type action that bacteria and cells use to move in a targeted fashion along a particular surface. The current research project aims to transplant this behaviour from bacterial systems into bio-based synthetic polymer networks, allowing the development of truly biomimetic mechanically adaptable materials. The aims of the project will be achieved by exploring a number of recently identified bacterial catch bonds, isolating the specific amino acid sequence responsible for this behaviour and using them to functionalise bio-based polymer chains. Using the receptor-ligand complexes specific to each bacterial adhesive, dynamic polymer networks will be constructed that display an adaptable response to force as observed in bacterial catch bonds. This represents an important area of research, for whilst the observation of ‘catch’ bond behaviour is relatively recent, their ability to revolutionise biomimetic materials is enormous. Their behaviour under stress is reminiscent of that of smooth muscle during peristaltic motion and materials mimicking this behaviour have the potential to drive new developments in synthetic organ and disease model research. Thoughout this project, fundamental insights will be gained into the intrinsic workings of bacterial catch bonds, specifically environmental factors affecting their behaviour, as well as how their behaviour is modified or scaled by inclusion in a macroscale material. The interdisciplinary project aims to push the boundaries of biology and materials science, from the molecular to the macroscale.
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The information about "CATCHGEL" are provided by the European Opendata Portal: CORDIS opendata.
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No valid XML
lastchecktime (2024-04-19 1:08:51) correctly updated