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GLYCO-WAY SIGNED

Glycomics of Winery Antimicrobial Yeast

Total Cost €

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EC-Contrib. €

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Partnership

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 GLYCO-WAY project word cloud

Explore the words cloud of the GLYCO-WAY project. It provides you a very rough idea of what is the project "GLYCO-WAY" about.

underlying    antibiotic    fine    mannan    center    industry    madrid    showed    structures    usa    saccharomyces    amr    biological    productive    intestinal    strategy    technological    billion    mitigating    uc    independence    healthcare    anti    cerevisiae    emergence    mainly    unravel    25k    strains    breakthroughs    hinders    structure    strengthen    resistance    mostly    microbiota    characterization    lacking    edge    polysaccharides    hypothesis    molecules    mechanism    reveal    line    nature    implementing    davis    cell    identification    microbial    subsequently    internationally    barrier    insights    yeast    science    toolsets    supplements    prebiotics    analytical    modulating    spain    combination    feed    challenged    effectiveness    heterogeneous    delays    deaths    food    expert    primitive    serious    infections    spread    burden    wine    generates    lab    annually    csic    isolated    professional    rudimentary    positive    transferred    glycomics    reference    barile    gut    mechanistic    action    cutting    significantly    employ    walls    glucan    gained   

Project "GLYCO-WAY" data sheet

The following table provides information about the project.

Coordinator
AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS 

Organization address
address: CALLE SERRANO 117
city: MADRID
postcode: 28006
website: http://www.csic.es

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
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 Coordinator Country Spain [ES]
 Total cost 263˙732 €
 EC max contribution 263˙732 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-GF
 Starting year 2020
 Duration (year-month-day) from 2020-04-29   to  2023-04-28

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS ES (MADRID) coordinator 263˙732.00
2    THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US (OAKLAND CA) partner 0.00

Map

 Project objective

The recent emergence and spread of anti-microbial resistance (AMR) generates serious concerns. AMR related infections result in 25K deaths and €1.5 billion healthcare costs in the EU annually. A promising strategy involves strengthening the intestinal barrier and modulating gut microbiota using prebiotics. Cell walls polysaccharides, mainly from S. cerevisiae, showed great potential for mitigating antibiotic burden. At present however, our understanding of the mechanism of action underlying these biological effects is significantly lacking, mostly due a rudimentary characterization which hinders identification of key molecules and delays the production of effective feed supplements. This primitive characterization is due to the heterogeneous nature of polysaccharides, which have challenged researchers for years. Recent technological breakthroughs now provide analytical toolsets that enable a more comprehensive understanding of the fine structure of large polysaccharides. Based on the hypothesis that other yeast strains will have the same positive effects than S. cerevisiae, this project will employ cutting edge Glycomics approaches to unravel mannan and glucan structures from the most widely used non-saccharomyces yeast strains in the wine industry, and subsequently evaluate their effectiveness, isolated and in combination, to reveal key mechanistic insights. The project will be carried out in The Barile Lab at the UC-Davis (USA), an internationally recognized center with experience in Glycomics applied to Food Science, and in the CSIC (Spain), one of the most productive research institution in EU. The knowledge gained by the applicant in Glycomics for Food Science will be transferred to the EU by implementing a European Reference Center in this field at CSIC (Madrid, Spain). The objectives proposed, will enable the applicant to become an expert in glycomics and strengthen his professional independence. The proposed research is in line with the H2020 objectives.

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The information about "GLYCO-WAY" are provided by the European Opendata Portal: CORDIS opendata.

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