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GLYCO-WAY SIGNED

Glycomics of Winery Antimicrobial Yeast

Total Cost €

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EC-Contrib. €

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Partnership

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 GLYCO-WAY project word cloud

Explore the words cloud of the GLYCO-WAY project. It provides you a very rough idea of what is the project "GLYCO-WAY" about.

breakthroughs    prebiotics    gut    polysaccharides    reveal    center    molecules    cutting    antibiotic    independence    transferred    hypothesis    glucan    resistance    significantly    healthcare    emergence    structures    toolsets    nature    lacking    strategy    uc    25k    challenged    mechanistic    effectiveness    deaths    microbial    davis    microbiota    generates    amr    walls    biological    strengthen    madrid    barrier    delays    cell    yeast    mostly    action    fine    characterization    primitive    glycomics    mitigating    modulating    wine    annually    productive    lab    infections    anti    science    mechanism    rudimentary    professional    feed    positive    industry    spread    mannan    identification    structure    burden    insights    serious    underlying    food    implementing    edge    isolated    showed    unravel    billion    mainly    analytical    cerevisiae    supplements    technological    hinders    csic    line    subsequently    internationally    reference    usa    saccharomyces    strains    combination    expert    barile    gained    spain    heterogeneous    intestinal    employ   

Project "GLYCO-WAY" data sheet

The following table provides information about the project.

Coordinator
AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS 

Organization address
address: CALLE SERRANO 117
city: MADRID
postcode: 28006
website: http://www.csic.es

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Total cost 263˙732 €
 EC max contribution 263˙732 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-GF
 Starting year 2020
 Duration (year-month-day) from 2020-04-29   to  2023-04-28

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS ES (MADRID) coordinator 263˙732.00
2    THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US (OAKLAND CA) partner 0.00

Map

 Project objective

The recent emergence and spread of anti-microbial resistance (AMR) generates serious concerns. AMR related infections result in 25K deaths and €1.5 billion healthcare costs in the EU annually. A promising strategy involves strengthening the intestinal barrier and modulating gut microbiota using prebiotics. Cell walls polysaccharides, mainly from S. cerevisiae, showed great potential for mitigating antibiotic burden. At present however, our understanding of the mechanism of action underlying these biological effects is significantly lacking, mostly due a rudimentary characterization which hinders identification of key molecules and delays the production of effective feed supplements. This primitive characterization is due to the heterogeneous nature of polysaccharides, which have challenged researchers for years. Recent technological breakthroughs now provide analytical toolsets that enable a more comprehensive understanding of the fine structure of large polysaccharides. Based on the hypothesis that other yeast strains will have the same positive effects than S. cerevisiae, this project will employ cutting edge Glycomics approaches to unravel mannan and glucan structures from the most widely used non-saccharomyces yeast strains in the wine industry, and subsequently evaluate their effectiveness, isolated and in combination, to reveal key mechanistic insights. The project will be carried out in The Barile Lab at the UC-Davis (USA), an internationally recognized center with experience in Glycomics applied to Food Science, and in the CSIC (Spain), one of the most productive research institution in EU. The knowledge gained by the applicant in Glycomics for Food Science will be transferred to the EU by implementing a European Reference Center in this field at CSIC (Madrid, Spain). The objectives proposed, will enable the applicant to become an expert in glycomics and strengthen his professional independence. The proposed research is in line with the H2020 objectives.

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The information about "GLYCO-WAY" are provided by the European Opendata Portal: CORDIS opendata.

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