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THERADNET SIGNED

International NETwork for training and innovations in THErapeutic RADiation

Total Cost €

0

EC-Contrib. €

0

Partnership

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 THERADNET project word cloud

Explore the words cloud of the THERADNET project. It provides you a very rough idea of what is the project "THERADNET" about.

treatment    personalized    expertise    therapy    innovation    mass    clinical    approximately    co    performed    alone    outgrowth    primary    science    60    innovations    outstanding    modalities    adverse    tissues    dampen    biologically    collaborations    premises    death    industry    combined    disease    prior    substantial    improvements    recurrence    immune    small    integration    medicine    health    tumor    radiotherapy    training    precision    radiobiology    pursuit    sectors    microenvironment    normal    close    situation    metabolism    patients    translational    dose    community    radiation    combatting    reactions    stimulate    individual    successful    optimized    cancer    50    resistance    models    understand    employability    academia    therapeutic    acquired    irradiated    international    widen    radiobiological    countries    integrating    standard    network    regrowth    cured    innovative    plasticity    biological    critical    students    intrinsic    cooperate    surrounding    care    altered    window    guarantee    45    despite    limiting    hypotheses    outcome    benefit    metastatic    multimodality   

Project "THERADNET" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITAT ZURICH 

Organization address
address: RAMISTRASSE 71
city: ZURICH
postcode: 8006
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Total cost 4˙026˙324 €
 EC max contribution 4˙026˙324 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2019
 Funding Scheme MSCA-ITN-ETN
 Starting year 2019
 Duration (year-month-day) from 2019-09-01   to  2023-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITAT ZURICH CH (ZURICH) coordinator 562˙553.00
2    THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD UK (OXFORD) participant 606˙345.00
3    INSTITUT CURIE FR (PARIS) participant 549˙604.00
4    UNIVERSITEIT MAASTRICHT NL (MAASTRICHT) participant 531˙239.00
5    UNIVERSITE CATHOLIQUE DE LOUVAIN BE (LOUVAIN LA NEUVE) participant 512˙640.00
6    TECHNISCHE UNIVERSITAET DRESDEN DE (DRESDEN) participant 505˙576.00
7    UNIVERSITAETSKLINIKUM ESSEN DE (ESSEN) participant 505˙576.00
8    WESTDEUTSCHES PROTONENTHERAPIEZENTRUM ESSEN (WPE) GGMBH DE (ESSEN) participant 252˙788.00

Map

 Project objective

Radiotherapy alone or in multimodality approaches is applied in 45-60% of all cancer patients, but despite technical innovations approximately only 50% are cured. Disease recurrence may be due to regrowth of the primary tumor or metastatic outgrowth. Intrinsic and acquired resistance of the tumor and adverse reactions in the co-irradiated surrounding normal tissues dampen a successful therapy outcome. Substantial improvements are now expected from biologically optimized, personalized radiotherapy. This network is built on the premises that integration of novel-emerging radiobiological and tumor-biological concepts into current standard-of-care will improve outcome of radiotherapy-treated cancer patients. As the field of radiobiology is small in individual countries, it is essential to cooperate on the European level to achieve a critical mass for innovation in research and training. The partners in this network will stimulate outstanding science to understand the plasticity of an altered tumor metabolism and tumor microenvironment, including the immune system, prior to, and in response to radiotherapy, as well as related dose-limiting adverse effects in normal tissues. Research and development of novel combined treatment modalities in these areas will be performed in models as close as possible to the clinical situation to evaluate their potential to widen the therapeutic window beyond standard-of-care. Students will benefit from outstanding expertise and collaborations within academia and industry integrating novel concepts into translational cancer and radiation research. This will guarantee high employability in various sectors of cancer research and precision medicine. The European community will benefit from the pursuit of innovative hypotheses, training of new researchers, and dissemination of knowledge. By combatting a major death-related disease in Europe, this project will raise health and bring long-term benefit to the European and international community.

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The information about "THERADNET" are provided by the European Opendata Portal: CORDIS opendata.

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