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VASCUGRAFT SIGNED

Strain-stiffening vascular graft with outstanding compliance

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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Project "VASCUGRAFT" data sheet

The following table provides information about the project.

Coordinator
CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL 

Organization address
address: OLSHAUSENSTRASSE 40
city: KIEL
postcode: 24118
website: http://www.uni-kiel.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 0 €
 EC max contribution 150˙000 € (0%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2019-PoC
 Funding Scheme ERC-POC-LS
 Starting year 2020
 Duration (year-month-day) from 2020-10-01   to  2022-03-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL DE (KIEL) coordinator 150˙000.00

Map

 Project objective

Cardiovascular diseases are one of the major causes of death in the EU and appropriate treatment remains challenging and expensive. Often, the only treatment option is the replacement of a native blood vessel, for example if a coronary artery bypass is needed. Although patient-derived vascular grafts remain the gold standard as a replacement of the original vessel, alternatives have to be found, as donor material is limited. Currently available synthetic grafts have several drawbacks in comparison to native blood vessels. The major drawback is the mismatch between the mechanical properties of the native vessel and the synthetic graft, thus causing major complications like intima hyperplasia. While the stress-strain-curve in synthetic grafts is linear and the grafts are relatively stiff, native blood vessels are soft and have a non-linear, strain-stiffening mechanical behavior. In our ERC Starting Grant CELLINSPIRED we have developed a material structure that allows us to mimic the strain-stiffening of blood vessels. We will employ our strain-stiffening materials in synthetic vascular grafts with broad applicability in the field of vascular surgery. Within the proposed project VASCUGRAFT we will fabricate demonstrators of such biomimetic vascular grafts and strive to find a company that licenses our invention and brings it on the national and international market.

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The information about "VASCUGRAFT" are provided by the European Opendata Portal: CORDIS opendata.

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lastchecktime (2022-09-28 15:50:37) correctly updated