Explore the words cloud of the METACYL project. It provides you a very rough idea of what is the project "METACYL" about.
The following table provides information about the project.
UNIVERSITA DEGLI STUDI DI PARMA
|Coordinator Country||Italy [IT]|
|Total cost||183˙473 €|
|EC max contribution||183˙473 € (100%)|
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
|Duration (year-month-day)||from 2020-09-01 to 2022-08-31|
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|1||UNIVERSITA DEGLI STUDI DI PARMA||IT (PARMA)||coordinator||183˙473.00|
Carbonylative C-H activations can lead to an unprecedented degree of molecular sophistication by combining the atom-economical insertion of CO with the green activation of unreactive C-H bonds. In striking contrast to ortho C-H acylation of arenes and heteroarenes (directing-group strategy) and para C-H ones (Friedel-Crafts chemistry), meta C-H acylations are almost completely unexplored. This proposal aims at the development of the first example of meta C-H acylation via mild carbonylation of arenes. Pivoting on this breakthrough, it will be possible to accomplish synthetic methods 1) for the efficient synthesis of hardly accessible organic compounds, 2) for the activation and carbonylation of meta C(sp2)-H bonds, 3) by employing transient directing group and 4) demonstrating the application of these protocols under continuous flow conditions.
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The information about "METACYL" are provided by the European Opendata Portal: CORDIS opendata.
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