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NeuroVascOme SIGNED

Gut microbiota-Neurovascular Interactions in Early Life

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 NeuroVascOme project word cloud

Explore the words cloud of the NeuroVascOme project. It provides you a very rough idea of what is the project "NeuroVascOme" about.

disruptions    fellowships    career    microbial    prevalent    resident    mechanistic    first    network    gateway    caesarean    modern    barrier    environment    academic    society    period    audiences    neurovascular    professional    homeostasis    antibiotic    link    strategy    hyperactivity    deficits    later    linked    stress    integrity    thereby    precisely    microbiome    industry    health    administration    maturation    life    deficit    informed    predisposing    exact    vulnerable    msca    milieu    occurs    adverse    accordance    aid    disorders    sensitive    outcomes    microbiota    concomitant    settings    regulating    brain    autism    managerial    composition    neurodevelopmental    postnatal    dysfunction    organism    disruptors    perturbations    turn    prenatal    altered    vital    additionally    day    bbb    public    leads    scientific    caused    external    ing    gut    shown    mental    neurovascome    disorder    rate    strengthen    shaping    function    skillset    alteration    blood    phases    impacting    training   

Project "NeuroVascOme" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK 

Organization address
address: WESTERN ROAD
city: Cork
postcode: T12 YN60
website: www.ucc.ie

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Ireland [IE]
 Total cost 196˙590 €
 EC max contribution 196˙590 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2019
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2020
 Duration (year-month-day) from 2020-06-01   to  2022-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK IE (Cork) coordinator 196˙590.00

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 Project objective

The prenatal and early postnatal life are particularly vulnerable phases for brain development, during which essential neurodevelopmental processes occur. One such vital process is the development of the neurovascular unit resulting in the formation of blood brain barrier (BBB), which is the gateway regulating access of the external milieu to the brain. Concomitant with the postnatal BBB development, the maturation of our resident gut microbiota also occurs during this sensitive period of early life. Altered gut microbial composition has been shown to affect BBB function and is increasingly being linked to adverse health outcomes including neurodevelopmental disorders, such as autism or attention deficit hyperactivity disorder. However, an exact mechanistic understanding of how this early life alteration in microbiota composition leads to brain dysfunction is not known. The NeuroVascOme project aims to investigate the link between early life microbiota perturbations and neurovascular development, which in turn is crucial for brain homeostasis. And more precisely, how are the different disruptors of microbiome in early life impacting the neurovascular/BBB integrity, thereby predisposing the organism to health deficits in later life. This is especially relevant for our modern-day society wherein early life microbiome disruptions caused by increased stress, antibiotic administration and caesarean delivery methods are widely prevalent. In accordance with the aims of the MSCA fellowships, NeuroVascOme project will greatly aid my career development by providing first rate training in academic and industry settings that will enhance my research skillset, foster my managerial abilities and strengthen my professional network. Additionally, public, industry, and scientific audiences will be informed about the outcomes of the project through a dissemination strategy that will aim to promote the role of early life environment in shaping mental health.

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The information about "NEUROVASCOME" are provided by the European Opendata Portal: CORDIS opendata.

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