DISCO
Targeted DISCOvery of novel cellulases and hemicellulases and their reaction mechanisms for hydrolysis of lignocellulosic biomass
| Coordinatore | TEKNOLOGIAN TUTKIMUSKESKUS VTT
Organization address
address: TEKNIIKANTIE 4 A contact info |
| Nazionalità Coordinatore | Finland [FI] |
| Totale costo | 4˙001˙460 € |
| EC contributo | 2˙985˙845 € |
| Programma | FP7-KBBE
Specific Programme "Cooperation": Food, Agriculture and Biotechnology |
| Code Call | FP7-KBBE-2007-1 |
| Funding Scheme | CP-FP |
| Anno di inizio | 2008 |
| Periodo (anno-mese-giorno) | 2008-08-01 - 2012-07-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
TEKNOLOGIAN TUTKIMUSKESKUS VTT
Organization address
address: TEKNIIKANTIE 4 A contact info |
FI (ESPOO) | coordinator | 0.00 |
| 2 |
"Institution of the Russian Academy of Sciences, A.N. Bach Institute of Biochemistry of RAS"
Organization address
address: Leninsky Prospect 33 contact info |
RU (MOSCOW) | participant | 0.00 |
| 3 |
AGRIFIRM GROUP BV
Organization address
address: BOOGSCHUTTERSTRAAT 1A contact info |
NL (APELDOORN) | participant | 0.00 |
| 4 |
BIOGOLD OU
Organization address
address: Lossi contact info |
EE (TALLINN) | participant | 0.00 |
| 5 |
BUDAPESTI MUSZAKI ES GAZDASAGTUDOMANYI EGYETEM
Organization address
address: MUEGYETEM RAKPART 3 contact info |
HU (BUDAPEST) | participant | 0.00 |
| 6 |
COOPERATIE CEHAVE LANDBOUWBELANG U.A.
Organization address
address: POORT VAN VEGHEL 4949 contact info |
NL (VEGHEL) | participant | 0.00 |
| 7 |
DYADIC NEDERLAND BV
Organization address
address: NIEUWE KANAAL 7 S contact info |
NL (Wageningen) | participant | 0.00 |
| 8 |
G R WRIGHT AND SONS LTD
Organization address
address: Ponders End Mills contact info |
UK (ENFIELD) | participant | 0.00 |
| 9 |
HELSINGIN YLIOPISTO
Organization address
address: YLIOPISTONKATU 4 contact info |
FI (HELSINGIN YLIOPISTO) | participant | 0.00 |
| 10 |
INSTITUTE OF FOOD RESEARCH
Organization address
address: "Norwich Research Park, Colney" contact info |
UK (NORWICH) | participant | 0.00 |
| 11 |
SEKAB E-TECHNOLOGY AB
Organization address
address: Hoerneborgsvaegen contact info |
SE (OERNSKOELDSVIK) | participant | 0.00 |
| 12 |
WAGENINGEN UNIVERSITY
Organization address
address: DROEVENDAALSESTEEG 4 contact info |
NL (WAGENINGEN) | participant | 0.00 |
Mappa
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Obiettivo del progetto (Objective)
'The aim of the proposed DISCO project is to develop more efficient and therefore more cost-effective cellulosic and hemicellulosic enzyme tools for the enhanced hydrolysis of pre-treated lignocellulosic biomass in simultaneous saccharification and fermentation (SSF) conditions for bioethanol production. The focus will be on enzymes having increased catalytic activity on various types of relevant European lignocellulosic biomass. In addition enzymes with lower affinity for lignin shall also be developed. Such enzymes would increase the effective amount of cellulases/ hemicellulases for cellulose hydrolysis. Furthermore the recycling of these enzymes would be applicable. The approach in this proposal is to discover the desired activities by combining classical and modern screening technologies. The enzymes will be produced in suitable host systems for industrial enzyme production. The project also focuses on elucidation of enzymatic hydrolysis mechanisms, about which there is a paucity of knowledge. The project will determine the limiting structural factors in these mechanisms by characterisation of the substrate during the course of the hydrolysis and the remaining recalcitrant residue. Synergy between different cellulase and hemicellulases components will also be addresses on the chosen lignocellulosic substrates. Furthermore, the project seeks to demonstrate the proof of concept with the cellulolytic enzymes in a pilot scale using the most relevant European feedstock pretreated wheat straw and related high-volume co-products.'
Introduzione (Teaser)
Bioethanol from plant material is a sustainable alternative to fossil fuels because the carbon dioxide (CO2) emitted is balanced out by the CO2 taken up by the plants as they grow. Scientists investigated production of second generation biofuels from forestry, agriculture and wood-based waste.