BATCIC
Bacteriophage Therapy for Catheter Infection Control
| Coordinatore | UNIVERSITY OF BRIGHTON
Organization address
address: "Lewes Road, Mithras House" contact info |
| Nazionalità Coordinatore | United Kingdom [UK] |
| Totale costo | 1˙078˙314 € |
| EC contributo | 1˙078˙314 € |
| Programma | FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) |
| Code Call | FP7-PEOPLE-2011-IAPP |
| Funding Scheme | MC-IAPP |
| Anno di inizio | 2012 |
| Periodo (anno-mese-giorno) | 2012-02-01 - 2016-01-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
UNIVERSITY OF BRIGHTON
Organization address
address: "Lewes Road, Mithras House" contact info |
UK (BRIGHTON) | coordinator | 371˙007.00 |
| 2 |
UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK
Organization address
address: Western Road contact info |
IE (CORK) | participant | 388˙826.00 |
| 3 |
BIOCONTROL LIMITED
Organization address
address: GEORGE STREET 79 contact info |
UK (ISLE OF WIGHT) | participant | 195˙525.00 |
| 4 |
TEAGASC - AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY
Organization address
address: Oak Park contact info |
IE (CARLOW) | participant | 122˙956.00 |
Mappa
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Obiettivo del progetto (Objective)
'The primary aim of this project is to develop novel bacteriophage based strategies to combat Proteus mirabilis catheter associated urinary tract infection (CAUTI), a prevalent health-care associated infection for which there are currently no effective countermeasures. Indwelling urethral catheters (IUC) are the most commonly deployed medical devices, it is estimated that ~100 million IUC are used annually in healthcare systems globally, which equates to ~190 catheterisations per minute. However, IUC are vulnerable to infection, undermining their utility, jeopardising patient welfare and posing a substantial economic burden on healthcare systems. Over 40% of CAUTIs may be attributed to P. mirabilis, which poses particular problems in the care of catheterised patients. P. mirabilis causes encrustation and blockage of catheters, leading to serious complications such as pyelonephritis, septicaemia and shock. It is difficult to eliminate from the catheterised urinary tract, even after the catheter is removed, and often causes chronic infection recalcitrant to conventional antibiotic therapy. Given the prolific use of IUC and corresponding prevalence of CAUTIs in healthcare systems across the world, development of bacteriophage based strategies for control of CAUTIs would open a niche in a global market that is projected to reach an annual value of €2 billion by 2015.'