FRACQUAL

Novel therapeutic agents to improve bone quality during fracture repair

 Coordinatore LUNDS UNIVERSITET 

 Organization address address: Paradisgatan 5c
city: LUND
postcode: 22100

contact info
Titolo: Prof.
Nome: Matti
Cognome: Ristinmaa
Email: send email
Telefono: 46462227987
Fax: +46 46 222 7370

 Nazionalità Coordinatore Sweden [SE]
 Totale costo 100˙000 €
 EC contributo 100˙000 €
 Programma FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call FP7-PEOPLE-2011-CIG
 Funding Scheme MC-CIG
 Anno di inizio 2012
 Periodo (anno-mese-giorno) 2012-01-01   -   2015-12-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    LUNDS UNIVERSITET

 Organization address address: Paradisgatan 5c
city: LUND
postcode: 22100

contact info
Titolo: Prof.
Nome: Matti
Cognome: Ristinmaa
Email: send email
Telefono: 46462227987
Fax: +46 46 222 7370

SE (LUND) coordinator 100˙000.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

center    bone    tissue    biomechanics    formed    treatments    fracture    complications    facilities    evaluation    university    hence    synchrotron    repair    newly    fractures    patients    excellent    quality    lund   

 Obiettivo del progetto (Objective)

'Supporting this application will enhance the changes for a well-known Swedish biomechanics researcher to relocate to Lund University and suceed with her long term goal to establish her research activities in Sweden. The proposal includes the use of highly advanced technology (engineering and physics) to evaluate novel treatments for bone fractures (orthopedics). Hence, it is truely multidisciplinary and requires the involvement of engineers, physicists, biologists and orthopedic surgeons within the collaborating environments. Fracture repair is a complex process, where about 5-10% of all fractures lead to complications. Complications are especially high in elderly patients with osteoporosis, where more effective treatment options are needed. This project evaluates the effect of newly developed potent bone modulating drugs during fracture repair in osteoporotic animals. Two animal models have been developed and are in use; the bone chamber and the open fracture healing model in rats. The evaluation methods involve highly modern biophysical evaluation techniques in order to determine and evaluate the quality of the newly formed tissue, to assess the treatments clinical potential. Hence, the project applies newly developed technology to study fracture repair and evaluate bone quality, including vascularization (in vivo microCT), composition (Synchrotron FTIR) and structure (Synchrotron SAXS), of the newly formed tissue. A successful outcome would result in enhanced quality of life for many patients. Lund University has long experience in developing novel biological treatments of fracture repair, and excellent technical experimental facilities, including MAX-lab synchrotron facilities, Biomedical Imaging center and Center for Biomechanics at Lund University. Hence, the match between the fellow, the project and the location is excellent.'

Altri progetti dello stesso programma (FP7-PEOPLE)

FOLDEG (2013)

Defining the pathways and mechanism of misfolded protein triage and quality control in eukaryotic cells

Read More  

DYNEFI (2010)

Dynamic Near Field Imaging

Read More  

PTSD AND SMOKING (2009)

Posttraumatic Stress Disorder and Smoking Cessation

Read More