CSP3OCF

Organocatalytic synthesis of fluorine compounds. Development of new methodologies for the enantioselective introduction of fluorine building blocks via CH activation of sp3 carbon

Coordinatore	UNIVERSITY OF SOUTHAMPTON    more  Organization address address: Highfield city: SOUTHAMPTON postcode: SO17 1BJ contact info Titolo: Ms. Nome: Yan Cognome: Qiao Email: send email Telefono: +4423 8059 3907
Nazionalità Coordinatore	United Kingdom [UK]
Totale costo	100˙000 €
EC contributo	100˙000 €
Programma	FP7-PEOPLE Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	FP7-PEOPLE-2013-CIG
Funding Scheme	MC-CIG
Anno di inizio	2013
Periodo (anno-mese-giorno)	2013-10-01   -   2017-09-30

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	UNIVERSITY OF SOUTHAMPTON  Organization address address: Highfield city: SOUTHAMPTON postcode: SO17 1BJ contact info Titolo: Ms. Nome: Yan Cognome: Qiao Email: send email Telefono: +4423 8059 3907	UK (SOUTHAMPTON)	coordinator	100˙000.00

Mappa

 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

 Obiettivo del progetto (Objective)

'The Project will deal with the activation of inert Csp3-H bonds and the enantioselective addition of fluorocarbon nucleophiles to lead to the enantioselective synthesis of fluorinated compounds. The impact of the research will be highly significant to several areas. First of all, a general method for a green and enantioselective synthesis of fluorine compounds through Csp3-H activation will represent a ground-breaking advance in the field and will interest organic chemists in general from both academic and industrial backgrounds. The development of new a green procedure that avoid the use of metals, and diminishes the generation of waste will have an important impact to chemical industry. Moreover the possibility to add a fluorine block in later stages synthesis through Csp3-H activation will be an important tool in the hit to led process in pharmaceutical industry, due the possibility to enhance the metabolic properties of active compounds by simply adding a fluorine residue.'