IMAGEMS

Exploring applications of spatial-map and velocity-map imaging mass spectrometry

 Coordinatore THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD 

Spiacenti, non ci sono informazioni su questo coordinatore. Contattare Fabio per maggiori infomrazioni, grazie.

 Nazionalità Coordinatore United Kingdom [UK]
 Totale costo 1˙499˙969 €
 EC contributo 1˙499˙969 €
 Programma FP7-IDEAS-ERC
Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call ERC-2007-StG
 Funding Scheme ERC-SG
 Anno di inizio 2008
 Periodo (anno-mese-giorno) 2008-06-01   -   2013-05-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD

 Organization address address: University Offices, Wellington Square
city: OXFORD
postcode: OX1 2JD

contact info
Titolo: Dr.
Nome: Claire
Cognome: Vallance
Email: send email
Telefono: -277000
Fax: -277231

UK (OXFORD) hostInstitution 0.00
2    THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD

 Organization address address: University Offices, Wellington Square
city: OXFORD
postcode: OX1 2JD

contact info
Titolo: Ms.
Nome: Linda
Cognome: Piálek
Email: send email
Telefono: +44 1865 289800
Fax: +44 1865 289801

UK (OXFORD) hostInstitution 0.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

spectrometer    explored    molecules    fragmentation    ions    mode    mass    spatial    instrument    map    dynamics    single    distributions    fragment    imaging    velocity   

 Obiettivo del progetto (Objective)

'Our aim is to develop a next-generation mass spectrometer with unique imaging capabilities. For each mass, the new instrument will image the complete velocity or spatial distribution of the ions at their point of formation. The velocity distributions of fragment ions are highly sensitive to the detailed dynamics of the fragmentation process, such that in velocity imaging mode the new instrument will provide a powerful alternative to conventional tandem mass spectrometry approaches for fragmentation studies. In addition to the mechanistic and structural information encoded the images, the set of photofragment velocity distributions constitutes a unique ‘fingerprint’ for the parent molecule that may be used in molecular identification. In spatial imaging mode, there are clear applications in the areas of surface analysis and high throughput sampling, both of which will be explored over the course of the project. The spectrometer will utilise the method of velocity/spatial-map imaging, a technique originally developed for studying the photofragmentation dynamics of small molecules. A standard velocity-map imaging measurement yields the detailed speed and angular distributions for a single fragment. However, by employing advanced detector technology, our instrument will be capable of recording such distributions for all fragments simultaneously, opening the way for the study of much larger molecules with complex fragmentation pathways. A working prototype of the spectrometer will be constructed within the first year of the project, with further developments and improvements taking place over the remaining four years. The instrument will be calibrated using results from previous studies, and its capabilities in both spatial and velocity-map imaging modes will then be explored using a number of carefully chosen chemical systems. These include fundamental dynamics studies, ultraviolet photodissociation of peptides, and imaging of biomolecules and single cells on surfaces.'

Altri progetti dello stesso programma (FP7-IDEAS-ERC)

CRC PROGRAMME (2008)

Dissecting the roles of the beta-catenin and Tcf genetic programmes during colorectal cancer progression

Read More  

ORGANOMET (2013)

Novel organometallic anticancer compounds

Read More  

EIMS (2012)

"Early infectious, inflammatory and immune mechanisms in schizophrenia"

Read More