PRIMATE HETEROTACHY

"The speed of molecular evolution: rate shifts, gene function and natural selection in primate history"

 Coordinatore THE UNIVERSITY OF READING 

 Organization address address: WHITEKNIGHTS CAMPUS WHITEKNIGHTS HOUSE
city: READING
postcode: RG6 6AH

contact info
Titolo: Ms.
Nome: Gemma
Cognome: Lowe
Email: send email
Telefono: +44 118 378 8977
Fax: +44 118 378 8979

 Nazionalità Coordinatore United Kingdom [UK]
 Totale costo 162˙568 €
 EC contributo 162˙568 €
 Programma FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call FP7-PEOPLE-IEF-2008
 Funding Scheme MC-IEF
 Anno di inizio 2009
 Periodo (anno-mese-giorno) 2009-11-01   -   2011-10-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    THE UNIVERSITY OF READING

 Organization address address: WHITEKNIGHTS CAMPUS WHITEKNIGHTS HOUSE
city: READING
postcode: RG6 6AH

contact info
Titolo: Ms.
Nome: Gemma
Cognome: Lowe
Email: send email
Telefono: +44 118 378 8977
Fax: +44 118 378 8979

UK (READING) coordinator 162˙568.66

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

humans    primate    gene    primates    rates    functions    evolution    classes    functional    human    genome    genes    species   

 Obiettivo del progetto (Objective)

'Which genes have shifted in evolutionary rates during the history of the Primates (monkeys, apes and humans); and what does the function of these genes tell us about adaptation in our Order? The aim of this proposal is to investigate changes in the speed of primate gene evolution, using complete genome sequences from at least six species of Primates augmented by data from other species in the Order, including Neanderthals. The specific aims of the proposal are i) to identify functional classes of genes (e.g. cognition and immune system) whose rates of evolution diverge from general trends in primate gene evolution, ii) to build a picture of the gene functions that characterise human evolution integrated over the 20,000 to 25,000 human genes, and iii) to relate these functional classes to selective processes at the level of primate ecology (e.g. parasitism, predation, mating system and social behaviour). The work will require novel bioinformatics and comparative methods that can identify genes whose evolution varies in rate and mode throughout the primate tree, and these be developed and made freely available to other scientists. By building on a wider set of species and genes than previously studied the results of the research will provide the first “whole genome functional map” perspective of the conserved and altered gene functions occurring during the evolution of the lineage leading to modern humans.'

Altri progetti dello stesso programma (FP7-PEOPLE)

BIOMACHINELEARNING (2014)

Bio-inspired Machine Learning for Chemical Sensing

Read More  

OXIOSCR (2013)

Oxford Innovative Organic Synthesis in Cancer Research Doctoral Programme

Read More  

ORTHOPROTACS (2013)

Design of orthogonal molecular probes targeting engineered von-Hippel Lindau (VHL) E3 ubiquitin ligase for the control of intracellular protein levels

Read More