ARCADE

Advancement of Research Capability for the Development of New Functional Compounds

 Coordinatore ETHNIKO IDRYMA EREVNON 

 Organization address address: Vassileos Constantinou Avenue 48
city: ATHENS
postcode: 11635

contact info
Titolo: Ms.
Nome: Petrohilou
Cognome: Ioanna
Email: send email
Telefono: 302107000000
Fax: 302107000000

 Nazionalità Coordinatore Greece [EL]
 Totale costo 3˙320˙818 €
 EC contributo 2˙449˙629 €
 Programma FP7-REGPOT
Specific Programme "Capacities": Research potential of Convergence Regions
 Code Call FP7-REGPOT-2009-1
 Funding Scheme CSA-SA
 Anno di inizio 2009
 Periodo (anno-mese-giorno) 2009-12-01   -   2013-05-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    ETHNIKO IDRYMA EREVNON

 Organization address address: Vassileos Constantinou Avenue 48
city: ATHENS
postcode: 11635

contact info
Titolo: Ms.
Nome: Petrohilou
Cognome: Ioanna
Email: send email
Telefono: 302107000000
Fax: 302107000000

EL (ATHENS) coordinator 2˙449˙629.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

international    greece    domc    pharmaceutical    capacity    functional    organisation    materials    arcade    workshops    reinforce    organic    expertise    conference    athens    capability    foundation    compounds    bioactive    mass    structure    medicinal    nhrf    synthesis    hellenic    infrastructure    iopc    chemistry    nmr    facility    spectrometry    groups    specialised    chemical    national   

 Obiettivo del progetto (Objective)

'The ARCADE project is to be coordinated by the Institute of Organic and Pharmaceutical Chemistry (IOPC) which is part of the National Hellenic Research Foundation (NHRF) situated in the Convergent Region of Attiki in Greece. The key concept behind ARCADE is that, in order to strengthen the research profile of the IOPC and to enable its members to participate effectively in research activities at a Community level of excellence, certain measures need to be taken in order to reinforce the institute’s research capability in areas where it has recognised expertise. The ARCADE project, therefore, addresses specific objectives designed to have maximal impact on the IOPC’s research activities that focus on the design and synthesis of functional compounds and, more particularly, of bioactive compounds and materials. The key concept of the project is to build on the Institute’s existing expertise in the design, synthesis and analysis of new compounds with potential applications in medicinal chemistry, catalysis and materials science. To this end it is planned to use the opportunities provided by the REGPOT action for:

- personnel exchanges with well-established partner groups in Belgium, Germany, Italy, the Netherlands, Spain, Slovenia, Switzerland and the UK to reinforce and transfer necessary know-how - the acquisition of new equipment and upgrade of existing infrastructure with the aim of providing state-of-the-art support for the IOPC’s research objectives and advancing, in particular, its capability in Mass Spectrometry and NMR spectroscopy - the recruitment of experienced researchers to fully exploit the newly acquired equipment and to provide added impetus to the IOPC’s research potential - the organisation of an international conference and a number of workshops in close collaboration with the heads of the partner groups, with topics related to core activities of the IOPC - the dissemination and the promotion of the objectives of the project to the wider public through a range of diverse activities.

A well-defined management structure has been drawn up which involves the research staff of the IOPC in all of the activities planned. In addition, an International Advisory Board of three distinguished scientists has also been arranged to offer counsel and to make an independent assessment of the project.'

Introduzione (Teaser)

The EU devotes considerable funding towards the reinforcement of research potential across Europe. Particular emphasis was placed on strengthening the infrastructure of the Division of Organic and Medicinal Chemistry (DOMC), part of the National Hellenic Research Foundation (NHRF) in Athens, Greece.

Descrizione progetto (Article)

The NHRF is a non-profit research organisation that was founded in 1958 and its research activities focus on history, biology and chemistry. On the chemical front, the work of the NHRF DOMC is devoted to the design and synthesis of functional compounds as well as bioactive compounds and materials. These could be used to target major diseases such as myocardial infarction, type 2 diabetes and cancer.

Wishing to expand its research potential, the EU-funded 'Advancement of research capability for the development of new functional compounds' (http://www.arcade-iopc.eu/ (ARCADE)) project focused on human and equipment infrastructure. The received funding was utilised to recruit more research personnel and to advance the existing equipment of the DOMC.

One of the key project activities entailed the establishment of a new mass spectrometry facility to increase the accuracy and sensitivity of detection of a series of chemical experiments. Combined with a protein purification facility and upgraded nuclear magnetic resonance (NMR) capacity, the ARCADE project aimed to substantially improve the capacity of DOMC to perform combinatorial research in the field of applied and structural chemistry. DOMC researchers will now be able to synthesise, purify and determine the complex structure of novel bioactive compounds of pharmaceutical significance.

To promote the activities of the project and highlight the improved research capacity of the DOMC, three specialised workshops and an International Conference on Chemistry for Health were organised in Athens in 2012. This has helped to reinforce existing collaborations and establish new ones with 14 European institutions.

Overall, the ARCADE project has contributed to enhancing the visibility of DOMC in the field of chemical research and highlighting its existing research activities at the international level. Importantly, the equipment infrastructure provides specialised state-of-the-art services in Greece and is believed to improve the quality of research at the national level. At NHRF alone, the activities of the ARCADE project have led to the submission of over 30 manuscripts to peer-reviewed journals.

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