VIRALPHYLOGEOGRAPHY

Evolutionary reconstruction of viral spread in time and space

 Coordinatore KATHOLIEKE UNIVERSITEIT LEUVEN 

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 Nazionalità Coordinatore Belgium [BE]
 Totale costo 1˙498˙915 €
 EC contributo 1˙498˙915 €
 Programma FP7-IDEAS-ERC
Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call ERC-2010-StG_20091118
 Funding Scheme ERC-SG
 Anno di inizio 2010
 Periodo (anno-mese-giorno) 2010-10-01   -   2015-09-30

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

 Organization address address: "FRANKLIN STREET 1111, 12 FLOOR"
city: OAKLAND CA
postcode: 94607

contact info
Titolo: Ms.
Nome: Martha
Cognome: Hansen
Email: send email
Telefono: +1 310 794 0236
Fax: +1 310 794 0631

US (OAKLAND CA) beneficiary 182˙614.95
2    THE UNIVERSITY OF EDINBURGH

 Organization address address: OLD COLLEGE, SOUTH BRIDGE
city: EDINBURGH
postcode: EH8 9YL

contact info
Titolo: Ms.
Nome: Angela
Cognome: Noble
Email: send email
Telefono: +44 131 650 9024
Fax: +44 131 651 4028

UK (EDINBURGH) beneficiary 134˙671.20
3    KATHOLIEKE UNIVERSITEIT LEUVEN

 Organization address address: Oude Markt 13
city: LEUVEN
postcode: 3000

contact info
Titolo: Dr.
Nome: Philippe
Cognome: Lemey
Email: send email
Telefono: -332144
Fax: -332115

BE (LEUVEN) hostInstitution 1˙181˙629.00
4    KATHOLIEKE UNIVERSITEIT LEUVEN

 Organization address address: Oude Markt 13
city: LEUVEN
postcode: 3000

contact info
Titolo: Dr.
Nome: Stijn
Cognome: Delauré
Email: send email
Telefono: +32 16 320 944
Fax: +32 16 324 198

BE (LEUVEN) hostInstitution 1˙181˙629.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

spatial    influenza    data    full    genetic    viral    pathogen    epidemic   

 Obiettivo del progetto (Objective)

'To identify the causal mechanisms leading to disease emergence, endemic maintenance and epidemic expansion, epidemiologists would benefit tremendously from a full characterization of pathogen spread in space and time. The extensive sequencing efforts for the ongoing swine-origin H1N1 influenza A epidemic testify that analyses of pathogen genetic data are becoming increasingly important source of information in epidemiology. The new era of metagenomics promises to harvest such data in unprecedented quantities with remarkable rapidity. With the objective to assist in designing effective intervention and prevention strategies, we propose to develop a comprehensive statistical framework for uncovering the spatial and temporal dynamics of pathogen genomes. To this aim, we will design and extend a series of computationally tractable models that use the rapidly proliferating viral genome data to their full potential, connect molecular evolution to underlying spatial processes, and pave the path to rigorous and powerful phylogeographic hypothesis testing approaches. Armed with these tools, we will investigate how genetic variation within important viral pathogens, such as influenza, rabies and HIV, arises and persists across a diverse range of hosts and environments.'

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