Opendata, web and dolomites

FAPIC SIGNED

Fast Assay for Pathogen Identification and Characterisation

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

Project "FAPIC" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITE LYON 1 CLAUDE BERNARD 

Organization address
address: BOULEVARD DU 11 NOVEMBRE 1918 NUM43
city: VILLEURBANNE CEDEX
postcode: 69622
website: www.univ-Iyon1.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Project website http://www.fapic.eu
 Total cost 5˙999˙997 €
 EC max contribution 5˙999˙997 € (100%)
 Programme 1. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-PHC-2014-two-stage
 Funding Scheme RIA
 Starting year 2015
 Duration (year-month-day) from 2015-05-01   to  2020-04-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITE LYON 1 CLAUDE BERNARD FR (VILLEURBANNE CEDEX) coordinator 718˙978.00
2    AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH AT (WIEN) participant 1˙352˙496.00
3    AXO SCIENCE SAS FR (LYON) participant 1˙041˙875.00
4    MOLZYM GMBH & CO KG DE (BREMEN) participant 914˙750.00
5    BEE ROBOTICS LTD UK (Caernarfon) participant 775˙875.00
6    THE UNIVERSITY OF WARWICK UK (COVENTRY) participant 540˙654.00
7    UNIVERSITEIT HASSELT BE (HASSELT) participant 336˙504.00
8    LYON INGENIERIE PROJETS FR (VILLEURBANNE) participant 146˙750.00
9    SVEUCILISTE U ZAGREBU MEDICINSKI FAKULTET HR (ZAGREB) participant 91˙250.00
10    STICHTING KATHOLIEKE UNIVERSITEIT NL (NIJMEGEN) participant 80˙865.00

Map

 Project objective

The emergence of highly diverse resistance mechanisms among pathogens requires their detailed analysis to guarantee an efficient medical treatment. The gold standard in clinical diagnostics is based on the cultivation of bacteria and their phenotypical characterisation. However, these methods are labour-intensive and time-consuming lasting in some cases up to a few weeks. Thus, faster diagnostic techniques are necessary to ensure an immediate and targeted treatment of the patient. DNA-based diagnostics can provide the relevant results within a few hours. The requirements for a clinical DNA-based characterisation method are high; more than 1000 clinically relevant antibiotic resistance genes, a few hundred phylogenetic marker genes and virulence factors have to be targeted (including SNP detection). The limit of detection has to be low because a few 100 bacterial cells in the blood system can lead to the death of the patient. It should be possible to analyse a wide range of clinical sample origins such as stool, blood, urine and saliva using the same test. In addition, the results have to be obtained within a single working day. In our project, we will develop two diagnostic systems that can be with direct sample material from patients. Thus, the time-consuming cultivation of pathogens will be avoided. Additionally, the test will be more sensitive, specific and faster than any other test on the market using an innovative DNA probe concept.

 Deliverables

List of deliverables.
Analysis of bacteremia pilot study teport Documents, reports 2020-04-01 17:13:52
Clinical advice on relevant targets, samples, patient populations Documents, reports 2020-04-01 17:13:52
Randomized and blinded panels Other 2020-04-01 17:13:52
Sample collection B Other 2020-04-01 17:13:52
Project handbook Documents, reports 2020-04-01 17:13:52

Take a look to the deliverables list in detail:  detailed list of FAPIC deliverables.

 Publications

year authors and title journal last update
List of publications.
2015 I. Roca, M. Akova, F. Baquero, J. Carlet, M. Cavaleri, S. Coenen, J. Cohen, D. Findlay, I. Gyssens, O.E. Heure, G. Kahlmeter, H. Kruse, R. Laxminarayan, E. Liébana, L. López-Cerero, A. MacGowan, M. Martins, J. Rodríguez-Baño, J.-M. Rolain, C. Segovia, B. Sigauque, E. Tacconelli, E. Wellington, J. Vila
The global threat of antimicrobial resistance: science for intervention
published pages: 22-29, ISSN: 2052-2975, DOI: 10.1016/j.nmni.2015.02.007
New Microbes and New Infections 6 2020-04-01
2016 Ramya Salimraj, Lihong Zhang, Philip Hinchliffe, Elizabeth M. H. Wellington, Jürgen Brem, Christopher J. Schofield, William H. Gaze, James Spencer
Structural and Biochemical Characterization of Rm3, a Subclass B3 Metallo-β-Lactamase Identified from a Functional Metagenomic Study
published pages: 5828-5840, ISSN: 0066-4804, DOI: 10.1128/AAC.00750-16
Antimicrobial Agents and Chemotherapy 60/10 2020-04-01
2015 Gregory C. A. Amos, Chiara Borsetto, Paris Laskaris, Martin Krsek, Andrew E. Berry, Kevin K. Newsham, Leo Calvo-Bado, David A. Pearce, Carlos Vallin, Elizabeth M. H. Wellington
Designing and Implementing an Assay for the Detection of Rare and Divergent NRPS and PKS Clones in European, Antarctic and Cuban Soils
published pages: e0138327, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0138327
PLOS ONE 10/9 2020-04-01
2018 Michaela Hendling, Stephan Pabinger, Konrad Peters, Noa Wolff, Rick Conzemius, Ivan Barišić
Oli2go: an automated multiplex oligonucleotide design tool
published pages: W252-W256, ISSN: 0305-1048, DOI: 10.1093/nar/gky319
Nucleic Acids Research 46/W1 2020-04-01
2015 Hayley C. King, Andrew Murphy, Phillip James, Emma Travis, David Porter, Jason Sawyer, Jennifer Cork, Richard J. Delahay, William Gaze, Orin Courtenay, Elizabeth M. Wellington
Performance of a Noninvasive Test for Detecting Mycobacterium bovis Shedding in European Badger (Meles meles) Populations
published pages: 2316-2323, ISSN: 0095-1137, DOI: 10.1128/JCM.00762-15
Journal of Clinical Microbiology 53/7 2020-04-01
2016 Branka Bedenić, Sanda Sardelić, Josefa Luxner, Zrinka Bošnjak, Dijana Varda-Brkić, Amarela Lukić-Grlić, Ivana Mareković, Sonja Frančula-Zaninović, Marija Krilanović, Dorotea Šijak, Andrea Grisold, Gernot Zarfel
Molecular characterization of class b carbapenemases in advanced stage of dissemination and emergence of class d carbapenemases in Enterobacteriaceae from Croatia
published pages: 74-82, ISSN: 1567-1348, DOI: 10.1016/j.meegid.2016.05.011
Infection, Genetics and Evolution 43 2020-04-01
2016 Branka Bedenić, Nataša Firis, Vesna Elveđi-Gašparović, Marija Krilanović, Krešimir Matanović, Iva Štimac, Josefa Luxner, Jasmina Vraneš, Tomislav Meštrović, Gernot Zarfel, Andrea Grisold
Emergence of multidrug-resistant Proteus mirabilis in a long-term care facility in Croatia
published pages: 404-413, ISSN: 0043-5325, DOI: 10.1007/s00508-016-1005-x
Wiener klinische Wochenschrift 128/11-12 2020-04-01

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "FAPIC" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "FAPIC" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.3.1.3.)

PanCareFollowUp (2019)

PanCareFollowUp: Novel, patient-centred survivorship care to improve care quality, effectiveness, cost-effectiveness and accessibility for survivors and caregivers

Read More  

LEGACy (2019)

CeLac and European consortium for a personalized medicine approach to Gastric Cancer

Read More  

GACD (2019)

Global Alliance for Chronic Diseases Secretariat

Read More