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DENOVO-RBC

Developing Novel and Optimal Additive Solutions for Red Blood Cells

Total Cost €

0

EC-Contrib. €

0

Partnership

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Project "DENOVO-RBC" data sheet

The following table provides information about the project.

Coordinator
HASKOLI ISLANDS 

Organization address
address: SAEMUNDARGOTU 2
city: REYKJAVIK
postcode: 101
website: www.hi.is

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Iceland [IS]
 Total cost 150˙000 €
 EC max contribution 150˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2014-PoC
 Funding Scheme ERC-POC
 Starting year 2015
 Duration (year-month-day) from 2015-03-01   to  2016-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    HASKOLI ISLANDS IS (REYKJAVIK) coordinator 150˙000.00

Map

 Project objective

'The research conducted in SYSTEM_US (ERC Advanced Grant #232816) has led to the discovery of valuable biomarkers for the quality of red blood cells (RBCs) in standard blood bank storage conditions. Using a combination of systems biology and metabolomics, this discovery will lead to the development of novel RBC storage technologies including additive solutions and diagnostics. These technologies will become valuable assets in the form of intellectual property to large transfusion medicine companies and will save thousands of lives over the coming decades. This proposal covers the needs to fully define the market and NPV of the developing technology, fully define the regulatory and clinical path of product approval, file for patents to protect the intellectual property, conduct necessary validation experiments, and continue to develop relations with industry contacts.'

 Publications

year authors and title journal last update
List of publications.
2016 G. Paglia, A. DAlessandro, O. Rolfsson, O. E. Sigurjonsson, A. Bordbar, S. Palsson, T. Nemkov, K. C. Hansen, S. Gudmundsson, B. O. Palsson
Biomarkers defining the metabolic age of red blood cells during cold storage
published pages: e43-e50, ISSN: 0006-4971, DOI: 10.1182/blood-2016-06-721688
Blood 128/13 2019-07-23
2016 Giuseppe Paglia, Ólafur E. Sigurjónsson, Aarash Bordbar, Óttar Rolfsson, Manuela Magnusdottir, Sirus Palsson, Kristine Wichuk, Sveinn Gudmundsson, Bernhard O. Palsson
Metabolic fate of adenine in red blood cells during storage in SAGM solution
published pages: 2538-2547, ISSN: 0041-1132, DOI: 10.1111/trf.13740
Transfusion 56/10 2019-07-23
2016 Aarash Bordbar, Pär I. Johansson, Giuseppe Paglia, Scott J. Harrison, Kristine Wichuk, Manuela Magnusdottir, Sóley Valgeirsdottir, Mikkel Gybel-Brask, Sisse R. Ostrowski, Sirus Palsson, Ottar Rolfsson, Olafur E. Sigurjónsson, Morten B. Hansen, Sveinn Gudmundsson, Bernhard O. Palsson
Identified metabolic signature for assessing red blood cell unit quality is associated with endothelial damage markers and clinical outcomes
published pages: 852-862, ISSN: 0041-1132, DOI: 10.1111/trf.13460
Transfusion 56/4 2019-07-23

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The information about "DENOVO-RBC" are provided by the European Opendata Portal: CORDIS opendata.

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