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BioStealth

Explore the potentialities of biostealth coatings for tissue engineering and reconstructive medicine

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 BioStealth project word cloud

Explore the words cloud of the BioStealth project. It provides you a very rough idea of what is the project "BioStealth" about.

cheap    capability    sick    lipids    interactions    mechanical    provides    changing    ideal    majority    opportunity    occurs    stable    fda    proper    attachment    quality    science    dipping    function    medicine    fouling    disturbs    triggers    financing    coated    advantages    reconstructive    interaction    either    chemistry    patients    host    mostly    implant    tunable    lipid    companies    restoring    biofouling    lack    implantation    markets    leave    cell    care    infections    biocompatible    industry    integration    biological    bio    approved    attractive    air    routes    composition    suitable    economic    absence    rehospitalization    limited    fail    materials    stability    coating    offers    conventional    biostealth    fast    market    introduction    breakthrough    produces    plasma    implants    expressed    business    conditioning    body    societal    combined    spraying    coatings    vivo    suggested    preconditioning    health    causing    hydrogels    engineering    public    caused    innovative    tissue    cells   

Project "BioStealth" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITEIT TWENTE 

Organization address
address: DRIENERLOLAAN 5
city: ENSCHEDE
postcode: 7522 NB
website: www.utwente.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 150˙000 €
 EC max contribution 150˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2014-PoC
 Funding Scheme ERC-POC
 Starting year 2015
 Duration (year-month-day) from 2015-02-01   to  2016-07-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITEIT TWENTE NL (ENSCHEDE) coordinator 150˙000.00

Map

 Project objective

BioStealth production of implant coatings provides an exciting business opportunity. BioStealth offers unique advantages of societal and economic importance, such as public health and sick leave.

Biocompatible materials, i.e. materials with proper cell response upon implantation, are attractive for restoring body function. Conventional implant coating methods lack in quality and therefore the majority, if not all, bio-coatings fail in proper interaction with host tissue, either caused by absence of biological triggers, biofouling or unwanted chemistry. This lack of proper interaction occurs fast upon implantation and disturbs specific cell interaction, eventually causing infections. Mostly, patients need rehospitalization which increase health care costs.

BioStealth produces easy and cheap implant coatings by dipping or spraying lipids. BioStealth lipid coatings are air-stable and suitable for in-vivo use. BioStealth can be applied to FDA approved implant materials without changing the mechanical properties, which is key for tissue engineering and reconstructive medicine. BioStealth coatings have a tunable composition which makes them an ideal coating to improve interactions with cells. These factors greatly enhance application potential.

Non-fouling lipids were suggested before, but as hydrogels are used for preconditioning implants, air-stability, fast procedures, tunable capability and the range of materials that can be coated and used in-vivo is very limited. In BioStealth innovative, robust conditioning of implants with plasma is used for lipid attachment, creating a breakthrough in integration of implants with tissue.

A business case will be developed for BioStealth, covering different markets and routes for market introduction. Results of market analysis and financing needs will be combined with science-based technology comparison and used for discussions with potential industry partners. Several companies have already expressed interest in BioStealth.

 Publications

year authors and title journal last update
List of publications.
2016 Shrikrishnan Sankaran, Jasper van Weerd, Jens Voskuhl, Marcel Karperien, Pascal Jonkheijm
Photoresponsive Cucurbit[8]uril-Mediated Adhesion of Bacteria on Supported Lipid Bilayers
published pages: 6187-6196, ISSN: 1613-6829, DOI: 10.1002/smll.201502471
Small 11 2019-07-23
2016 Liulin Yang, Aijie Liu, Shuqin Cao, Rindia M. Putri, Pascal Jonkheijm, and Jeroen J. L. M. Cornelissen
Self-Assembly of Proteins: Towards Supramolecular Materials
published pages: 15570-15582, ISSN: 1521-3765, DOI: 10.1002/chem.201601943
Chem Eur J 22 2019-07-23

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The information about "BIOSTEALTH" are provided by the European Opendata Portal: CORDIS opendata.

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