Opendata, web and dolomites


LincRNA and encoded small peptides: Functional discovery in development and evolution

Total Cost €


EC-Contrib. €






Project "lincPeptEvolDev" data sheet

The following table provides information about the project.


Organization address
address: HERZL STREET 234
postcode: 7610001

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Israel [IL]
 Project website
 Total cost 182˙509 €
 EC max contribution 182˙509 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-RI
 Starting year 2015
 Duration (year-month-day) from 2015-05-01   to  2017-04-30


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    WEIZMANN INSTITUTE OF SCIENCE IL (REHOVOT) coordinator 182˙509.00


 Project objective

Beyond the paradigm of the central dogma of biology lie a number of recently discovered elements that are nonetheless central to cellular function. Eukaryotic genomes express an unexpectedly wide variety of functional long transcripts that do not encode major proteins, called long non-coding RNAs (lncRNAs), whose functions are still poorly understood. More recent work has uncovered the prevalence of small open reading frames (smORFs) encoded within both mRNA and lncRNAs, only a few of which have evidence of active translation and function. The work in this proposal focuses on these relatively uncharacterized layers of biological regulation, and aims to harness the power of insect developmental genetics and the exquisite knowledge of axial patterning in embryos to probe the function of small peptides/lncRNA. Developmental gene networks in insects with varied modes of development have been studied in detail, allowing insights into how such networks have evolved. I will use a combination of state-of-the-art comparative genomics and transcriptome analysis, molecular genetics, biochemistry, and ribosome profiling to identify transcripts encoding putative small peptides with conserved features across insects, which represent novel components of developmental networks. This will be accompanied by genetic studies illuminating their functional interactions within developmental networks, including embryonic expression and loss of function phenotypes. Our approach to studying small peptides includes creation of innovative functional assays needed in the field, and is relevant to understanding the function of small peptides in all animals.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "LINCPEPTEVOLDEV" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email ( and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "LINCPEPTEVOLDEV" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

FOCUSIS (2020)

Focal volume Control Using Structured Illumination Sources

Read More  

ToMComputations (2019)

How other minds are represented in the human brain: Neural computations underlying Theory of Mind

Read More  

EPIC (2019)

Evolution of Planktonic Gastropod Calcification

Read More