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MOTOR SIMULATION

Motor simulation: Evaluating the role of mirror neurons in humans through ECOG and Lesion Studies

Total Cost €

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EC-Contrib. €

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Partnership

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Project "MOTOR SIMULATION" data sheet

The following table provides information about the project.

Coordinator
THE HEBREW UNIVERSITY OF JERUSALEM 

Organization address
address: EDMOND J SAFRA CAMPUS GIVAT RAM
city: JERUSALEM
postcode: 91904
website: www.huji.ac.il

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Israel [IL]
 Project website https://scholar.google.co.il/citations
 Total cost 263˙385 €
 EC max contribution 263˙385 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-GF
 Starting year 2015
 Duration (year-month-day) from 2015-07-01   to  2018-06-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE HEBREW UNIVERSITY OF JERUSALEM IL (JERUSALEM) coordinator 263˙385.00
2    THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US (OAKLAND CA) partner 0.00

Map

 Project objective

One of the most intriguing, yet controversial findings in neuroscience in the past two decades is the discovery of the mirror neuron system (MNS). These visuo-motor neurons discharge both when a monkey does a particular goal-directed action and also when it observes another individual doing a similar action. The result of this mechanism is thought to be the capacity to recognize that an individual is performing an action, to differentiate this action from others analogous to it, and to use this information in order to act appropriately. This mechanism has been proposed as the basis for social cognition, and deficits in social understanding, such as those seen in autism spectrum disorder, have been linked to deficits in the MNS. Here I propose to use 2 novel approaches to address the neurobiological and behavioral significance of the human mirror neuron system (hMNS). (a) I will use Electrocorticography (ECoG) in neurosurgical patients to assess where, when, and how neurons in the prefrontal, parietal and sensorimotor regions are involved in action recognition. (b) I will employ scalp EEG and behavioral measures in a unique cohort of patients with damage centered in the Inferior Frontal Gyrus (IFG) or the Inferior Parietal Lobule (IPL). If the IFG and IPL are the core regions of the hMNS, patients with lesions to these regions should show deficits in understanding others’ actions, intentions and emotions (when these are expressed by body motion). This research will further our knowledge on the neural underpinnings of social understanding, and on the consequences of deficits in these neural networks.

 Publications

year authors and title journal last update
List of publications.
2016 Perry, Anat, Sandy J. Lwi, Alice Verstaen, Callum Dewar, Robert W. Levenson, and Robert T. Knight.
The role of the orbitofrontal cortex in regulation of interpersonal space: evidence from frontal lesion and frontotemporal dementia patients
published pages: 1894-1901, ISSN: 1749-5016, DOI:
Social cognitive and affective neuroscience 11 2019-06-13
2016 Perry Anat, Ben-Ami Bartal Inbal
The Neurobiology of Empathy
published pages: , ISSN: , DOI:
Countertransference in Perspective, The double-edged sword of the patient-therapist emotional relationship 2019-06-13
2016 Ben-Ami Bartal Inbal, Perry Anat
The Evolution of Pro-social Behavior
published pages: , ISSN: , DOI:
Countertransference in Perspective, The double-edged sword of the patient-therapist emotional relationship 2019-06-13
2016 Jennifer Stiso, Anat Perry
How Do We Understand Other People?
published pages: , ISSN: 2296-6846, DOI: 10.3389/frym.2016.00018
Frontiers for Young Minds 4 2019-06-13
2017 Perry, Anat, Jennifer Stiso, Edward F. Chang, Jack J. Lin, Josef Parvizi, and Robert T. Knight
Mirroring in the Human Brain: Deciphering the Spatial-Temporal Patterns of the Human Mirror Neuron System
published pages: 1-10, ISSN: 1047-3211, DOI:
Cerebral Cortex 2019-06-13
2017 Perry, Anat, Samantha N. Saunders, Jennifer Stiso, Callum Dewar, Jamie Lubell, Torstein R. Meling, Anne-Kristin Solbakk, Tor Endestad, and Robert T. Knight
Effects of prefrontal cortex damage on emotion understanding: EEG and behavioural evidence
published pages: 1086-1099., ISSN: 0006-8950, DOI:
Brain 140 2019-06-13

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