Explore the words cloud of the MultiNav project. It provides you a very rough idea of what is the project "MultiNav" about.
The following table provides information about the project.
STICHTING KATHOLIEKE UNIVERSITEIT
|Coordinator Country||Netherlands [NL]|
|Total cost||177˙598 €|
|EC max contribution||177˙598 € (100%)|
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
|Duration (year-month-day)||from 2015-05-01 to 2017-04-30|
Take a look of project's partnership.
|1||STICHTING KATHOLIEKE UNIVERSITEIT||NL (NIJMEGEN)||coordinator||177˙598.00|
In Europe 30M people are visually impaired (VI), 2.5M of which are entirely blind. Despite many efforts on the societal level, VIs are still ‘left in the dark’, when it comes to independent navigation. Neuroscience has the long-term potential to provide brain-prostheses, which circumvent damaged parts of the visual system. In the present project, we will investigate how spatial information can assist VIs during navigation by non-invasive and invasive information delivery. We will make use of multisensory integration and optogenetic stimulation to investigate these questions in an animal model of navigation in the dark. Mice use their sensory hairs (‘whiskers’) analogous to how VIs use their cane for exploring their local surroundings. During this tactile navigation VIs also utilize the sound generated by their cane to provide both spatial and material information about their surroundings, evidence for a multisensory strategy. Specifically we will first investigate the effect of multisensory information on the neural representation of tactile information during natural exploratory behaviour. For this purpose we will provide sounds rapidly (<1ms) in sync with each surface contact of the whisker. These sounds are modulated by the animal’s distance to the object or will provide contextually relevant spatial information (e.g. distant targets). We predict that even soft auditory information will boost the usefulness of tactile information (‘inverse effectiveness’) and allow faster behavioural judgments in a spatial task. Next, we will provide spatial information directly to the tactile cortex using optogenetic stimulation, emulating the functioning of future, spatial brain prostheses. We predict that animals will learn to integrate this additional information to optimize their navigation success. In summary, our research will contribute to providing navigation information to VIs non-invasively and invasively, and thus further the ongoing efforts of inclusion in Europe.
|year||authors and title||journal||last update|
Yves Boubenec, Jennifer Lawlor, Urszula GÃ³rska, Shihab Shamma, Bernhard Englitz
Detecting changes in dynamic and complex acoustic environments
published pages: , ISSN: 2050-084X, DOI: 10.7554/eLife.24910
Chao Huang, Andrey Resnik, Tansu Celikel, Bernhard Englitz
Adaptive Spike Threshold Enables Robust and Temporally Precise Neuronal Encoding
published pages: e1004984, ISSN: 1553-7358, DOI: 10.1371/journal.pcbi.1004984
|PLOS Computational Biology 12/6||2019-07-24|
Jesse J. Heckman, R?mi Proville, Gert J. Heckman, Alireza Azarfar, Tansu Celikel, Bernhard Englitz
High-precision spatial localization of mouse vocalizations during social interaction
published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-017-02954-z
|Scientific Reports 7/1||2019-07-24|
Christian Keine, Rudolf R?bsamen, Bernhard Englitz
Inhibition in the auditory brainstem enhances signal representation and regulates gain in complex acoustic environments
published pages: , ISSN: 2050-084X, DOI: 10.7554/eLife.19295
Jesse Heckman, Brigit McGuinness, Tansu Celikel, Bernhard Englitz
Determinants of the mouse ultrasonic vocal structure and repertoire
published pages: 313â€“325, ISSN: 0149-7634, DOI: 10.1016/j.neubiorev.2016.03.029
|Neuroscience and Biobehavioral Reviews 65||2019-07-24|
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The information about "MULTINAV" are provided by the European Opendata Portal: CORDIS opendata.
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