Explore the words cloud of the MolNANOtox project. It provides you a very rough idea of what is the project "MolNANOtox" about.
The following table provides information about the project.
UNITED KINGDOM RESEARCH AND INNOVATION
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|Coordinator Country||United Kingdom [UK]|
|Total cost||195˙454 €|
|EC max contribution||195˙454 € (100%)|
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
|Duration (year-month-day)||from 2015-10-05 to 2018-03-18|
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|1||UNITED KINGDOM RESEARCH AND INNOVATION||UK (SWINDON)||coordinator||195˙454.00|
|2||NATURAL ENVIRONMENT RESEARCH COUNCIL||UK (SWINDON WILTSHIRE)||coordinator||0.00|
As nanotechnology continues to advance at an exponential rate, new products are continuously introduced into the market for research and consumer use. Engineered nanomaterials (ENMs), the functional components in these products, are often specifically designed to exploit the unique properties that nanomaterials exhibit; however, there is a widespread uncertainty on how these new properties may also potentially translate into novel risk issues in the environment. In particular, their high specific surface area and surface reactivity may promote distinct interactions with organisms particularly at the lower trophic levels. This can depend on both the intrinsic and extrinsic properties of ENMs, and can be affected by the formation of an “eco-corona”, which is composed of environmentally derived macromolecules from the milieu in which the ENMs are exposed that adsorb to the ENMs surface. However, understanding these interactions at the molecular level and their mechanistic consequences are severely limited and technically challenging, requiring a cross discipline approach. This project aims to address this knowledge gap by uncovering the underlying mechanisms for the formation and persistence of eco-coronas on a range of ENMs by combining fundamental ENM chemistry, environmental toxicology, advanced optical and mass spectroscopy and imaging techniques. In particular, this project will apply surface enhanced spectroscopic methods to characterise eco-corona composition and evolution and how this affects ENM interactions with, and impact upon unicellular organisms. By correlating the eco-corona composition with uptake route (or accumulation at external membrane) and toxicity response, and by investigating how these ENMs are partitioned within model species, the project proposes to identify the molecular basis that determines the fate and toxicology of ENMs in the environment.
|year||authors and title||journal||last update|
Ryo Sekine, Katie L. Moore, Marianne Matzke, Pascal Vallotton, Haibo Jiang, Gareth M. Hughes, Jason K. Kirby, Erica Donner, Chris R. M. Grovenor, Claus Svendsen, Enzo Lombi
Complementary Imaging of Silver Nanoparticle Interactions with Green Algae: Dark-Field Microscopy, Electron Microscopy, and Nanoscale Secondary Ion Mass Spectrometry
published pages: 10894-10902, ISSN: 1936-0851, DOI: 10.1021/acsnano.7b04556
|ACS Nano 11/11||2019-06-18|
Ryo Sekine, Ezzat R. Marzouk, Maryam Khaksar, Kirk G. Scheckel, John P. Stegemeier, Gregory V. Lowry, Erica Donner, Enzo Lombi
Aging of Dissolved Copper and Copper-based Nanoparticles in Five Different Soils: Short-term Kinetics vs. Long-term Fate
published pages: 1198, ISSN: 0047-2425, DOI: 10.2134/jeq2016.12.0485
|Journal of Environment Quality 46/6||2019-06-18|
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