Opendata, web and dolomites

MOGLYNET SIGNED

Modulation of glycolytic flux as a new approach for treatment of atherosclerosis and plaque stabilization: a multidisciplinary study

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 MOGLYNET project word cloud

Explore the words cloud of the MOGLYNET project. It provides you a very rough idea of what is the project "MOGLYNET" about.

secondments    relies    stress    network    12    foundation    industry    optimization    discovery    forces    angiogenesis    learning    outcomes    player    glycolysis    public    excellence    exposure    edge    outreach    molecular    transfer    aging    join    outlast    supervision    external    drug    pfkfb3    groups    platform    academic    cooperation    innovative    collaborations    cutting    vivo    training    area    therapy    universities    disseminating    esrs    stage    attract    schools    summer    pathological    doctoral    establishing    pharma    complementary    language    activities    networking    multidisciplinary    engagement    joint    atherosclerosis    solid    moglynet    enterprises    pursue    sharing    inter    oxidative    workshops    disease    quality    train    tackle    transferable    academia    expertise    model    employment    educational    skills    scientific    mission    material    relationships    generation    structures    industrial    convey    attractive    professionals    doctorate    esr    enzyme    intersectorial   

Project "MOGLYNET" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITA DEGLI STUDI DI MILANO 

Organization address
address: Via Festa Del Perdono 7
city: MILANO
postcode: 20122
website: www.unimi.it

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Project website http://www.moglynet.com/website/
 Total cost 3˙086˙435 €
 EC max contribution 3˙086˙435 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2015
 Funding Scheme MSCA-ITN-EJD
 Starting year 2015
 Duration (year-month-day) from 2015-09-01   to  2019-11-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITA DEGLI STUDI DI MILANO IT (MILANO) coordinator 1˙032˙245.00
2    THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN UK (ABERDEEN) participant 546˙575.00
3    ACADEMISCH ZIEKENHUIS LEIDEN NL (LEIDEN) participant 510˙748.00
4    UNIVERSITEIT ANTWERPEN BE (ANTWERPEN) participant 501˙120.00
5    UNIVERSITAT DE BARCELONA ES (BARCELONA) participant 495˙745.00
6    BAYER IT (Milano) partner 0.00
7    BIOMAX INFORMATICS AG DE (PLANEGG) partner 0.00
8    EIPG FR (PARIS) partner 0.00
9    HistoGeneX N.V. BE (Berchem) partner 0.00
10    KEMOTECH SRL IT (PULA) partner 0.00
11    LINKCARE HEALTH SERVICES SL ES (BARCELONA) partner 0.00
12    PHARMINTRACO CH (Barbengo) partner 0.00
13    PPD IT (Segrate Milano) partner 0.00

Map

 Project objective

The mission of MoGlyNet is to define a joint doctorate educational training model in Drug Discovery and Development where Academia and Industry join their forces for: - creating a common platform of knowledge and language for early stage researchers (ESR) working in the Drug Discovery and Development area aiming to convey complementary pharma-skills - exploiting this platform to train a new generation of cutting-edge researchers and professionals highly attractive for employment by the European Pharma-industry - establishing structures for long-term cooperation, strengthening the relationships among the leading Universities and Pharma-enterprises and to continuously develop the research training platform that European industry relies on. To achieve the above objectives the main tasks of MoGlyNet are: - to attract/train 12 ESRs in optimization joint academic/industrial program of cutting-edge training-by-research, high quality supervision, complementary and transferable Pharma-skills training, inter-network secondments, and workshops/Summer Schools - to pursue an innovative research project that will tackle a timely and important scientific problem with a multidisciplinary approach (from molecular modelling to in vivo studies). Atherosclerosis is an aging-related disease and our research approach for a better therapy of atherosclerosis will be focused on the PFKFB3 enzyme, a key player in glycolysis/oxidative stress and therefore in pathological angiogenesis - to build a solid foundation for long-term European excellence in this field by disseminating MoGlyNet research/training outcomes and best practice into the partners Doctoral Schools, and by fostering long-term partnerships and collaborations that will outlast the Consortium - to transfer expertise/know-how among the Consortium participants and to external groups via networking activities, intersectorial exposure, secondments, workshops, sharing of learning material, public engagement and outreach activities

 Deliverables

List of deliverables.
At least 12 papers acknowledging the project published Other 2020-03-27 09:18:17
Statement on individual training, local courses, technical and transferable skills acquired (at each network meeting) Other 2020-03-27 09:18:08
At least 6 papers acknowledging the project published Other 2020-02-20 16:32:39
2 Summer schools organized Other 2020-02-20 16:32:39
2 Workshops on Scientific training Other 2020-02-20 16:32:39
Network Meetings Organized (including virtual meeting) Other 2020-02-20 16:32:39
EThics - delivery of documents Documents, reports 2020-02-20 16:32:38
Consortium web-site creation and scientific blog Websites, patent fillings, videos etc. 2020-02-20 16:32:38
Sueprvisory Board meeting Documents, reports 2020-02-20 16:32:38
Recruitment advertising publication Websites, patent fillings, videos etc. 2020-02-20 16:32:38

Take a look to the deliverables list in detail:  detailed list of MOGLYNET deliverables.

 Publications

year authors and title journal last update
List of publications.
2018 Reginald V.C.T. van der Kwast, Eva van Ingen, Laura Parma, Hendrika A.B. Peters, Paul H.A. Quax, A. Yaël Nossent
Adenosine-to-Inosine Editing of MicroRNA-487b Alters Target Gene Selection After Ischemia and Promotes Neovascularization
published pages: 444-456, ISSN: 0009-7330, DOI: 10.1161/circresaha.117.312345
Circulation Research 122/3 2020-02-20
2019 Sarath Babu Nukala, Luca Regazzoni, Giancarlo Aldini, Erika Zodda, Olga Tura-Ceide, Nicholas L. Mills, Marta Cascante, Marina Carini, Alfonsina D’Amato
Differentially Expressed Proteins in Primary Endothelial Cells Derived From Patients With Acute Myocardial Infarction
published pages: 947-956, ISSN: 0194-911X, DOI: 10.1161/hypertensionaha.119.13472
Hypertension 74/4 2020-02-20
2018 Paolo Gelosa, Laura Castiglioni, Marco Tenconi, Ludovico Baldessin, Giorgio Racagni, Alberto Corsini, Stefano Bellosta
Pharmacokinetic drug interactions of the non-vitamin K antagonist oral anticoagulants (NOACs)
published pages: 60-79, ISSN: 1043-6618, DOI: 10.1016/j.phrs.2018.07.016
Pharmacological Research 135 2020-02-20
2019 Helena Macut, Xiao Hu, Delia Tarantino, Ettore Gilardoni, Francesca Clerici, Luca Regazzoni, Alessandro Contini, Sara Pellegrino, Maria Luisa Gelmi
Tuning PFKFB3 Bisphosphatase Activity Through Allosteric Interference
published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-019-56708-0
Scientific Reports 9/1 2020-02-20
2019 M. R. de Vries, L. Parma, H. A. B. Peters, A. Schepers, J. F. Hamming, J. W. Jukema, M. J. T. H. Goumans, L. Guo, A. V. Finn, R. Virmani, C. K. Ozaki, P. H. A. Quax
Blockade of vascular endothelial growth factor receptor 2 inhibits intraplaque haemorrhage by normalization of plaque neovessels
published pages: 59-74, ISSN: 0954-6820, DOI: 10.1111/joim.12821
Journal of Internal Medicine 285/1 2020-02-20
2019 Valérie Françoise Smolders, Erika Zodda, Paul H. A. Quax, Marina Carini, Joan Albert Barberà, Timothy M. Thomson, Olga Tura-Ceide, Marta Cascante
Metabolic Alterations in Cardiopulmonary Vascular Dysfunction
published pages: , ISSN: 2296-889X, DOI: 10.3389/fmolb.2018.00120
Frontiers in Molecular Biosciences 5 2020-02-20
2018 \"Helena Macut DISFARM - Section of General and Organic Chemistry \"\"A. Marchesini\"\", University of Milan, Via Venezian 21, 20133 Milan, Italy. ; Xiao Hu; Delia Tarantino; Luca Giovanni Regazzoni; Ettore Gilardoni; Sara Pellegrino; Maria Luisa Gelmi\"
DESIGN, SYNTHESIS AND IN VITRO EVALUATION OF PFKFB3 PHOSPHATASE ACTIVITY ALLOSTERIC MODULATORS
published pages: , ISSN: , DOI: 10.5281/zenodo.1415341
International Symposium on Medicinal Chemistry Lublijana 2020-02-20
2018 L. Parma, M.R. De Vries, H.A.B. Peters and P.H.A. Quax
“Small molecule mediated inhibition of bFGF reduces in vivo angiogenesis and is a promising candidate to combat intraplaque angiogenesis in atherosclerosis”
published pages: , ISSN: , DOI: 10.5281/zenodo.1478821
ESM-EVBO summer school 2020-02-20
2018 H. Macut, X. Hu, D. Tarantino, L. Parma, S. Pellegrino, M. L. Gelmi
“Design, synthesis and in vitro evaluation of modulators of PFKFB3 phosphatase activity”
published pages: , ISSN: , DOI: 10.5281/zenodo.1478786
Marie Curie Alumni Association General Assembly and Annual Conference, 2020-02-20
2017 Cristofori, Virginia
Structure-based design and synthesis of new PFKFB3 kinase inhibitors as candidate therapeutics for treating atherosclerosis
published pages: , ISSN: , DOI: 10.5281/zenodo.827178
Winter Symposium 16th and 17th of February, Aberdeen University 2020-02-20
2017 Carlo, De Dominicis
Synthesis of PFKFB3 inhibitors for Positron Emission Tomography imaging of atherosclerotic plaque
published pages: , ISSN: , DOI: 10.5281/zenodo.827185
Graduate School 2017 Winter Symposium at the University of Aberdeen 2 2020-02-20
2017 Besa Emini Veseli, Paola Perrotta, Gregory R.A. De Meyer, Lynn Roth, Carole Van der Donckt, Wim Martinet, Guido R.Y. De Meyer
Animal models of atherosclerosis
published pages: 3-13, ISSN: 0014-2999, DOI: 10.1016/J.EJPHAR.2017.05.010
European Journal of Pharmacology 816 2020-02-20
2016 Baganha F., De Vries M. and Quax P.
In vivo evaluation by optical and PET imaging of IP angiogenesis and validation of PFKFB3 inhibitors in a murine vein graft model
published pages: , ISSN: , DOI: 10.5281/zenodo.832534
Dutch Heart Foundation 2020-02-20
2018 Irene Maffucci, Xiao Hu, Valentina Fumagalli, Alessandro Contini
An Efficient Implementation of the Nwat-MMGBSA Method to Rescore Docking Results in Medium-Throughput Virtual Screenings
published pages: , ISSN: 2296-2646, DOI: 10.3389/fchem.2018.00043
Frontiers in Chemistry 6 2020-02-20
2017 Fabiana Baganha; Erna Peters; Margreet de Vries; Knut Pettersson; Paul H.A. Quax
Humanized IgG monoclonal anti-phosphorylcholine reduces vein graft failure
published pages: , ISSN: , DOI: 10.5281/zenodo.832549
ESVS spring meeting 2017 2020-02-20
2017 Anahita Abdali, Helena Macut, Xiao Hu, Sara Pellegrino, Alberto Corsini, Maria Luisa Gelmi, Stefano Bellosta
Novel MMP-inhibiting peptides for stabilizing atherosclerotic plaques
published pages: e47-e48, ISSN: 0021-9150, DOI: 10.1016/j.atherosclerosis.2017.06.162
Atherosclerosis 263 2020-02-20
2017 Rob C. M. de Jong, Mark M. Ewing, Margreet R. de Vries, Jacco C. Karper, Antonius J. N. M. Bastiaansen, Hendrika A. B. Peters, Fabiana Baghana, Peter J. van den Elsen, Céline Gongora, J. Wouter Jukema, Paul H. A. Quax
The epigenetic factor PCAF regulates vascular inflammation and is essential for intimal hyperplasia development
published pages: e0185820, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0185820
PLOS ONE 12/10 2020-02-20
2017 Laura Parma, Fabiana Baganha, Paul H.A. Quax, Margreet R. de Vries
Plaque angiogenesis and intraplaque hemorrhage in atherosclerosis
published pages: 107-115, ISSN: 0014-2999, DOI: 10.1016/j.ejphar.2017.04.028
European Journal of Pharmacology 816 2020-02-20
2018 Margreet R. de Vries, Paul H. A. Quax
Inflammation in Vein Graft Disease
published pages: , ISSN: 2297-055X, DOI: 10.3389/fcvm.2018.00003
Frontiers in Cardiovascular Medicine 5 2020-02-20
2016 Cristofori, Virginia; Contini, Alessandro
Virtual screening approach in drug discovery targeting the PFKFB3 kinase binding site
published pages: , ISSN: , DOI: 10.5281/zenodo.826382
eCheminfo workshop in Drug Design, 18-22 July 2016 University of Milan 2020-02-20
2016 V. Smolders, O. Tura-Ceide, J. Garcia-Lucio, L. Piccari, V. I. Peinado, M. Castella, J. A. Barberà.
\"\"\"Derivation and characterisation of endothelial cells from patients with chronic thromboembolic pulmonary hypertension\"\"\"
published pages: , ISSN: , DOI: 10.5281/zenodo.826133
Jornadas Docencia CIBERES/CIBER-BBN 2016. 2020-02-20
2018 Valérie Françoise Smolders; Joan Albert Barberà; Olga Tura-Ceide
Derivation and characterization of endothelial cells from patients with chronic thromboembolic pulmonary hypertension
published pages: , ISSN: , DOI: 10.5281/zenodo.1402522
ATS 2018 2018, San Diego (CA), USA. 2020-02-20
2017 Valérie Françoise Smolders; Joan Albert Barberà; Olga Tura-Ceide
Dysfunctional endothelial cells in patients with chronic thromboembolic pulmonary hypertension
published pages: , ISSN: , DOI: 10.5281/zenodo.1402475
ERS 2017 2020-02-20
2016 E. Zodda, A. Jayaraman, P. de Atauri, S. Marin, R. Messeguer, O. Tura-Ceide, T. M Thomson, M. Cascante
“Study of central carbon metabolism of Endothelial Cells in normal and pathological conditions”
published pages: , ISSN: , DOI: 10.5281/zenodo.826394
EMBO conference 2020-02-20
2016 Parma L, M. R. De Vries, P. H. A. Quax
“In vitro and in vivo study on the effects of inhibitors of angiogenesis in atherosclerosis”
published pages: , ISSN: , DOI: 10.5281/zenodo.1478817
PhD course Dutch Heart Foundation, 2020-02-20
2018 Smolders, Valérie F.
Annual Research Day: Project summary for Elevator Pitch
published pages: , ISSN: , DOI: 10.5281/zenodo.1402470
\'Kaag dag : Annual Research meeting Leiden, 1 2020-02-20
2016 M. de Vries, L. Parma, E. Peters, J. Hamming, M.- J. Goumans, P. Quax
“P-140 VEGFR2 blockade in murine atherosclerotic vein grafts enhances plaque stability and reduces intraplaque haemorrhage by enhancement of plaque neovessel maturation”
published pages: , ISSN: , DOI: 10.5281/zenodo.1478810
Perspectives in Vascular Biology meeting , Frankfurt, 2020-02-20
2017 Erika Zodda; Anusha Jayaraman; Pedro de Atauri; Ramon Messeguer; Olga Tura-Ceide; Timothy M. Thomson; Marta Cascante
Metabolic characterization of endothelial cells dysfunctionality associated to acute myocardial infarction
published pages: , ISSN: , DOI: 10.5281/zenodo.1342612
ENABLE Conference - The 1st European PhD and Postdoc, 15-17 Noviembre 2017, Palau Casades , Barcelona (Spain) 2020-02-20
2017 L. Parma, C. De Dominicis, H. A. B. Peters, M. R. De Vries and P. H. A. Quax
“In vitro study on the effects of inhibitors of angiogenesis in atherosclerosis”
published pages: , ISSN: , DOI: 10.5281/zenodo.826048
ESVS spring meeting in Leiden, May 19-20, 2017. 2020-02-20
2017 V. Smolders, Olga Tura-Ceide, Jéssica Garcia-Lucio, Lucilla Piccari, Victor I. Peinado, Manel Castella, Joan Albert Barberà .
“Derivation and characterization of endothelial cells from patients with chronic thromboembolic pulmonary hypertension”
published pages: , ISSN: , DOI: 10.5281/zenodo.826143
spring meeting in Leiden 2020-02-20
2017 Cristofori, Virginia; Stanzione, Francesca; Zanda, Matteo; Contini, Alessandro
Structure-based design and synthesis of new PFKFB3 kinase inhibitors as candidate therapeutics for treating atherosclerosis
published pages: , ISSN: , DOI: 10.5281/zenodo.826380
Medicinal Chemistry Residential Summer School 2020-02-20
2016 Margreet de Vries; Laura Parma; Erna Peters; Jaap Hamming; Marie-José Goumans; Paul Quax
VEGFR2 blockade reduces intraplaque haemorrhage and enhances plaque stability by augmentation of plaque neovessel maturation
published pages: , ISSN: , DOI: 10.5281/zenodo.831473
International Vascular Biology Meeting (IVBM), Boston, Massachusetts, USA, 30 Oct – 03 Nov, 2016 2020-02-20
2018 Valerie smolders
Dysfunctional endothelial cells in patients with chronic thromboembolic pulmonary hypertension
published pages: , ISSN: , DOI: 10.5281/zenodo.1557576
2 Reunión de Investigación en Hipertensión Pulmonar. 2020-02-20
2018 Baganha F., M.R. De Vries, Erna Peters, Knut Pettersson and P.H.A. Quax
“A monoclonal human IgG1 phosphorylcholine antibody reduces vein graft remodelling, angiogenesis and intraplaque haemorrhage”
published pages: , ISSN: , DOI: 10.5281/zenodo.1489044
RVMM Meeting 2020-02-20
2017 F. Baganha, M.R. De Vries, Erna Peters, Knut Pettersson and P.H.A. Quax
F“A monoclonal human IgG1 phosphorylcholine antibody reduces vein graft remodelling, angiogenesis and intraplaque haemorrhage”
published pages: , ISSN: , DOI: 10.5281/zenodo.1489038
Rembrandt Symposium 2020-02-20
2018 Baganha F. , M.R. De Vries, Erna Peters, Knut Pettersson and P.H.A. Quax
“Humanized IgG monoclonal anti-phosphorylcholine reduces vein graft failure”
published pages: , ISSN: , DOI: 10.5281/zenodo.1489028
AIO research meeting 2020-02-20
2017 Cristofori V.
Drug discovery and Computation Biology
published pages: , ISSN: , DOI: 10.5281/zenodo.1486103
PechaKucha Night 2020-02-20
2018 Baganha F., M.R. De Vries, Erna Peters, Knut Pettersson and P.H.A. Quax
“A monoclonal human IgG1 phosphorylcholine antibody reduces vein graft remodelling, angiogenesis and intraplaque haemorrhage”
published pages: , ISSN: , DOI: 10.5281/zenodo.1489036
International Vascular Biology Meeting 2020-02-20
2018 F. Baganha, M.R. De Vries, Erna Peters, Knut Pettersson and P.H.A. Quax
“A monoclonal human IgG1 phosphorylcholine antibody reduces vein graft remodelling, angiogenesis and intraplaque haemorrhage”
published pages: , ISSN: , DOI: 10.5281/zenodo.1488964
Frontiers in Cardiovascular 2020-02-20
2016 HU, XIAO CONTINI, ALESSANDRO
Combining 3D-RISM with hydrophatic characteristic water evaluation: first step preparation for further PLANTS virtual screening with flexible explicit water molecules
published pages: , ISSN: , DOI:
2020-02-20
2016 HU, XIAO CONTINI, ALESSANDRO
Combining 3D-RISM with hydropathic charateristic water evaluation: first step preparation for further PLANTS virtual screening with flexible explicit water molecules
published pages: , ISSN: , DOI:
2020-02-20
2017 MACUT, HELENA; HU, XIAO; GELMI, MARIA LUISA; PELLEGRINO, SARA; TARANTINO, DELIA
Design, synthesis and in vitro evaluation of modulators of PFKFB3 autoregulatory domain
published pages: , ISSN: , DOI:
2020-02-20
2016 H. Macut, S. Pellegrino, M.L. Gelmi
Synthesis and characterization of the autoregulatory domain of PFKFB3
published pages: 137, ISSN: , DOI:
International Symposium on Medicinal Chemistry : book of abstracts 2020-02-20
2017 ABDALI, ANAHITA MACUT, HELENA PELLEGRINO, SARA GELMI, MARIA LUISA BELLOSTA, STEFANO
Novel MMP-inhibiting peptides for stabilizing atherosclerotic plaques
published pages: , ISSN: , DOI:
2020-02-20

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "MOGLYNET" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "MOGLYNET" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.1.)

MARSoluT (2019)

Managed Aquifer Recharge Solutions Training Network

Read More  

EuroPLEx (2019)

European network for Particle physics, Lattice field theory and Extreme computing

Read More  

CORAL (2020)

COntrolling network RAndom Lasers on chip

Read More