Opendata, web and dolomites


Harvesting the Sun

Total Cost €


EC-Contrib. €






 SUNLIGHTING project word cloud

Explore the words cloud of the SUNLIGHTING project. It provides you a very rough idea of what is the project "SUNLIGHTING" about.

scientific    attainable    amounts    industry    invigorated    adaptable    demonstrated    breakthroughs    plants    sustainable    structural    optimization    provides    chain    greenhouse    medium    algae    libraries    solar    offers    prescribed    food    proof    drugs    2025    profitable    flavors    final    mixtures    points    moss    easily    horizon2020    screening    ingredients    powered    hotspot    optimize    biology    fragrances    domain    contain    class    made    market    compounds    synthetic    ingenol    financial    originate    opportunity    edge    medicines    discovery    re    angelate    poc    industrial    representing    host    entry    erc    diterpenoids    full    functionalities    cultivate    world    forskolin    of    40    isolation    rare    exit    50    job    medicinal    harmony    biobased    diterpenoid    goals    grant    entirely    biological    envisioned    platform    difficult    cells    vision    combinatorial    constitute    excreted    competitive    commercial    pipelines    cyanobacteria    analogs    green    extraction    desired    structures    europe2020    potent    predicted   

Project "SUNLIGHTING" data sheet

The following table provides information about the project.


Organization address
address: NORREGADE 10
postcode: 1165

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Denmark [DK]
 Total cost 142˙783 €
 EC max contribution 142˙783 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2015-PoC
 Funding Scheme ERC-POC
 Starting year 2015
 Duration (year-month-day) from 2015-11-01   to  2017-04-30


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KOBENHAVNS UNIVERSITET DK (KOBENHAVN) coordinator 142˙783.00


 Project objective

Biological production of high-value compounds such as medicines, flavors, fragrances and food ingredients, is predicted to constitute 50% of the World market by 2025 thus representing a commercial hotspot. A competitive edge for European industry within this domain is therefore important. Today, 40% of prescribed medicinal drugs originate or are derived from rare or difficult to cultivate medicinal plants which typically contain the compounds in very low amounts and in complex mixtures. We have demonstrated that by using synthetic biology we can build a solar powered platform for production of key high-value compounds within the diterpenoid class in green cells (cyanobacteria/moss/algae). The diterpenoids are excreted into the growth medium offering easy isolation. This provides a highly profitable and attainable opportunity to produce a large number of medicinal compounds at highly reduced costs. The production platform is easily adaptable to make structural analogs and entirely new structures. Combinatorial libraries can be developed to enable screening for desired new functionalities. The envisioned production platform includes the full chain from pathway discovery, host optimization, scale-up, extraction and final product isolation and offers entry points for industrial development and exit points for adaptation to existing pipelines. Based on the advances made within the ERC Advanced Grant the focus of this PoC is to optimize the scientific breakthroughs’ market adaptation, specifically focused on the compounds Forskolin and Ingenol-3-angelate as proof-of-concept of the market value of the production platform. The envisioned full-chain focus offers potent financial opportunities and a new vision for biobased production across Europe in a re-invigorated sustainable greenhouse industry offering new job opportunities in full harmony with the envisioned Europe2020 and Horizon2020 goals.


year authors and title journal last update
List of publications.
2016 Thiyagarajan Gnanasekaran, Daniel Karcher, Agnieszka Zygadlo Nielsen, Helle Juel Martens, Stephanie Ruf, Xenia Kroop, Carl Erik Olsen, Mohammed Saddik Motawie, Mathias Pribil, Birger Lindberg Møller, Ralph Bock, Poul Erik Jensen
Transfer of the cytochrome P450-dependent dhurrin pathway from Sorghum bicolor into Nicotiana tabacum chloroplasts for light-driven synthesis
published pages: 2495-2506, ISSN: 0022-0957, DOI: 10.1093/jxb/erw067
Journal of Experimental Botany 67/8 2019-06-19
2016 Silas Busck Mellor, Agnieszka Zygadlo Nielsen, Meike Burow, Mohammed Saddik Motawia, Dainius Jakubauskas, Birger Lindberg Møller, Poul Erik Jensen
Fusion of Ferredoxin and Cytochrome P450 Enables Direct Light-Driven Biosynthesis
published pages: 1862-1869, ISSN: 1554-8929, DOI: 10.1021/acschembio.6b00190
ACS Chemical Biology 11/7 2019-06-19
2017 Jean-Etienne Bassard, Birger Lindberg Møller, Tomas Laursen
Assembly of Dynamic P450-Mediated Metabolons—Order Versus Chaos
published pages: 37-51, ISSN: 2198-6428, DOI: 10.1007/s40610-017-0053-y
Current Molecular Biology Reports 3/1 2019-06-19
2016 Kim Olsson, Simon Carlsen, Angelika Semmler, Ernesto Simón, Michael Dalgaard Mikkelsen, Birger Lindberg Møller
Microbial production of next-generation stevia sweeteners
published pages: , ISSN: 1475-2859, DOI: 10.1186/s12934-016-0609-1
Microbial Cell Factories 15/1 2019-06-19
2017 Irini Pateraki, Johan Andersen-Ranberg, Niels Bjerg Jensen, Sileshi Gizachew Wubshet, Allison Maree Heskes, Victor Forman, Björn Hallström, Britta Hamberger, Mohammed Saddik Motawia, Carl Erik Olsen, Dan Staerk, Jørgen Hansen, Birger Lindberg Møller, Björn Hamberger
Total biosynthesis of the cyclic AMP booster forskolin from Coleus forskohlii
published pages: , ISSN: 2050-084X, DOI: 10.7554/eLife.23001
eLife 6 2019-06-19
2016 Johan Andersen-Ranberg, Kenneth Thermann Kongstad, Morten Thrane Nielsen, Niels Bjerg Jensen, Irini Pateraki, Søren Spanner Bach, Britta Hamberger, Philipp Zerbe, Dan Staerk, Jörg Bohlmann, Birger Lindberg Møller, Björn Hamberger
Expanding the Landscape of Diterpene Structural Diversity through Stereochemically Controlled Combinatorial Biosynthesis
published pages: 2142-2146, ISSN: 1433-7851, DOI: 10.1002/anie.201510650
Angewandte Chemie International Edition 55/6 2019-06-19

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