Opendata, web and dolomites

AUTOSTEM SIGNED

Development of closed, scalable and AUTOmated robotic systems for therapeutic STEM cell manufacturing: aseptic systems from “Donor-to-Patient”

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

Project "AUTOSTEM" data sheet

The following table provides information about the project.

Coordinator
NATIONAL UNIVERSITY OF IRELAND GALWAY 

Organization address
address: UNIVERSITY ROAD
city: Galway
postcode: H91
website: www.nuigalway.ie

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Ireland [IE]
 Project website http://www.autostem2020.eu
 Total cost 5˙995˙761 €
 EC max contribution 5˙995˙761 € (100%)
 Programme 1. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-PHC-2015-two-stage
 Funding Scheme RIA
 Starting year 2016
 Duration (year-month-day) from 2016-01-01   to  2018-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    NATIONAL UNIVERSITY OF IRELAND GALWAY IE (Galway) coordinator 849˙375.00
2    FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. DE (MUNCHEN) participant 1˙207˙041.00
3    UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK IE (Cork) participant 757˙353.00
4    CROSPON LIMITED IE (GALWAY) participant 685˙000.00
5    ASTON UNIVERSITY UK (BIRMINGHAM) participant 549˙913.00
6    ZELLWERK GMBH DE (OBERKRAMER) participant 498˙750.00
7    UNIVERSITA DEGLI STUDI DI GENOVA IT (GENOVA) participant 450˙000.00
8    ORBSEN THERAPEUTICS LIMITED IE (Galway) participant 448˙375.00
9    CELL THERAPY CATAPULT LIMITED UK (LONDON) participant 299˙952.00
10    PINTAIL LTD IE (Blackrock) participant 250˙000.00

Map

 Project objective

AUTOSTEM will develop closed, scaleable and automated systems for therapeutic cell manufacture. The project vision is a donor-to-patient system where all aspects of processing, from tissue harvest to patient delivery are fully closed and aseptic. The process will involve new methods of biological cell selection from marrow, fat or other tissues, bioreactors to achieve scale and media formulations that are fully xeno-free. Process monitoring will utilise remote sensing and the automated retrieval of cells for microscopy, flow cytometry, karyotyping, differentiation or other tests. The final product will be a cryobag containing a specified cell dose, ready for thawing and clinical delivery.

AUTOSTEM will be the factory of the future for therapeutic cell manufacturing. This system could ultimately be scaled for hospital-based use to produce autologous cells or at industrial scale for allogeneic therapy. It will achieve consistent cell production, minimise contamination, maximise scale and reduce cost of goods, thus enabling routine clinical use of cell therapies.

The consortium will be a partnership of academic centres and industry with expertise across the disciplines relevant to the research and development goals. It will also include expertise in GMP and regulatory compliance and in healthcare economic analysis.

 Publications

year authors and title journal last update
List of publications.
2016 Richard P Harrison, Qasim A Rafiq, Nicholas Medcalf
Automating decentralized manufacturing of cell & gene therapy products
published pages: 489-497, ISSN: 2059-7800, DOI: 10.18609/cgti.2016.059
Cell and Gene Therapy Insights 2/4 2020-01-30
2016 Richard P Harrison, Qasim A Rafiq & Nicholas Medcalf
Cell and gene therapy manufacturing: the necessity for a cost-based development approach
published pages: 489-497, ISSN: 2059-7800, DOI: 10.18609/cgti.2016.014
Cell and Gene Therapy Insights 2/1 2020-01-30

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "AUTOSTEM" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "AUTOSTEM" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.3.1.3.)

LEGACy (2019)

CeLac and European consortium for a personalized medicine approach to Gastric Cancer

Read More  

PanCareFollowUp (2019)

PanCareFollowUp: Novel, patient-centred survivorship care to improve care quality, effectiveness, cost-effectiveness and accessibility for survivors and caregivers

Read More  

INTE-AFRICA (2019)

Integrating and decentralising diabetes and hypertension services in Africa

Read More