Explore the words cloud of the AUTOSTEM project. It provides you a very rough idea of what is the project "AUTOSTEM" about.
The following table provides information about the project.
NATIONAL UNIVERSITY OF IRELAND GALWAY
|Coordinator Country||Ireland [IE]|
|Total cost||5˙995˙761 €|
|EC max contribution||5˙995˙761 € (100%)|
1. H2020-EU.3.1.3. (Treating and managing disease)
|Duration (year-month-day)||from 2016-01-01 to 2018-12-31|
Take a look of project's partnership.
|1||NATIONAL UNIVERSITY OF IRELAND GALWAY||IE (Galway)||coordinator||849˙375.00|
|2||FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.||DE (MUNCHEN)||participant||1˙207˙041.00|
|3||UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK||IE (Cork)||participant||757˙353.00|
|4||CROSPON LIMITED||IE (GALWAY)||participant||685˙000.00|
|5||ASTON UNIVERSITY||UK (BIRMINGHAM)||participant||549˙913.00|
|6||ZELLWERK GMBH||DE (OBERKRAMER)||participant||498˙750.00|
|7||UNIVERSITA DEGLI STUDI DI GENOVA||IT (GENOVA)||participant||450˙000.00|
|8||ORBSEN THERAPEUTICS LIMITED||IE (Galway)||participant||448˙375.00|
|9||CELL THERAPY CATAPULT LIMITED||UK (LONDON)||participant||299˙952.00|
|10||PINTAIL LTD||IE (Blackrock)||participant||250˙000.00|
AUTOSTEM will develop closed, scaleable and automated systems for therapeutic cell manufacture. The project vision is a donor-to-patient system where all aspects of processing, from tissue harvest to patient delivery are fully closed and aseptic. The process will involve new methods of biological cell selection from marrow, fat or other tissues, bioreactors to achieve scale and media formulations that are fully xeno-free. Process monitoring will utilise remote sensing and the automated retrieval of cells for microscopy, flow cytometry, karyotyping, differentiation or other tests. The final product will be a cryobag containing a specified cell dose, ready for thawing and clinical delivery.
AUTOSTEM will be the factory of the future for therapeutic cell manufacturing. This system could ultimately be scaled for hospital-based use to produce autologous cells or at industrial scale for allogeneic therapy. It will achieve consistent cell production, minimise contamination, maximise scale and reduce cost of goods, thus enabling routine clinical use of cell therapies.
The consortium will be a partnership of academic centres and industry with expertise across the disciplines relevant to the research and development goals. It will also include expertise in GMP and regulatory compliance and in healthcare economic analysis.
|year||authors and title||journal||last update|
Richard P Harrison, Qasim A Rafiq, Nicholas Medcalf
Automating decentralized manufacturing of cell & gene therapy products
published pages: 489-497, ISSN: 2059-7800, DOI: 10.18609/cgti.2016.059
|Cell and Gene Therapy Insights 2/4||2020-01-30|
Richard P Harrison, Qasim A Rafiq & Nicholas Medcalf
Cell and gene therapy manufacturing: the necessity for a cost-based development approach
published pages: 489-497, ISSN: 2059-7800, DOI: 10.18609/cgti.2016.014
|Cell and Gene Therapy Insights 2/1||2020-01-30|
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The information about "AUTOSTEM" are provided by the European Opendata Portal: CORDIS opendata.
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