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Liqbiopsens

Reliable Novel Liquid Biopsy technology for early detection of colorectal cancer

Total Cost €

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EC-Contrib. €

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Partnership

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Project "Liqbiopsens" data sheet

The following table provides information about the project.

Coordinator
ADVANCED WAVE SENSORS S.L. 

Organization address
address: C/ CISCAR 40-8
city: VALENCIA
postcode: 46005
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Project website http://www.liqbiopsens.com
 Total cost 2˙702˙268 €
 EC max contribution 2˙307˙200 € (85%)
 Programme 1. H2020-EU.2.1.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT))
 Code Call H2020-ICT-2015
 Funding Scheme IA
 Starting year 2016
 Duration (year-month-day) from 2016-01-01   to  2018-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    ADVANCED WAVE SENSORS S.L. ES (VALENCIA) coordinator 415˙668.00
2    UNIVERSITE CATHOLIQUE DE LOUVAIN BE (LOUVAIN LA NEUVE) participant 501˙625.00
3    IDRYMA TECHNOLOGIAS KAI EREVNAS EL (IRAKLEIO) participant 450˙000.00
4    SERVICIO ANDALUZ DE SALUD ES (SEVILLA) participant 433˙750.00
5    DESTINA GEONOMICS LTD UK (EDINBOURGH) participant 386˙281.00
6    SISTEMAS GENOMICOS SL ES (PATERNA) participant 119˙875.00
7    BEABLE SL ES (MADRID) participant 0.00

Map

 Project objective

The overall aim of LIQBIOPSENS project is the further development and validation in real settings of a novel diagnostic platform for the early and fast detection of ctDNA and their KRAS and BRAF mutations associated to colorectal cancer through blood samples. The main features of LIQBIOPSENS are: reliability (detection rates vary from 95–100 %), low-cost (40-50 € per sample analysis), sensitivity (in the zM range), multiplexing capabilities (analysis of 27 KRAS and BRAF mutations simultaneously), short analysis time (30-60 min.), user-friendly interface and flexibility. Solution proposed by the LIQBIOPSENS project relies on the multidisciplinary integration of different Key Enabled Technologies: microelectronics, microfluidics, nanomaterials and genomics. In particular, LIQBIOPSENS platform is based on the integration of two novel complementary technologies. On the one hand, the revolutionary DGL© technology property of DestiNA Genomics Ltd, capable of delivering faster, more error-free detection of nucleic acids and their mutations than current enzyme-based detection systems, making 'false positive' results a thing of the past. On the other hand, a novel high resolution acoustic wave microsensor technology property of AWSensors, that allows an accurate, inexpensive, label-free, direct and real time transduction method to quantitatively evaluate the results of the application of the above mentioned DGL© technique.

 Deliverables

List of deliverables.
Project Website Websites, patent fillings, videos etc. 2019-10-03 19:01:14
Multicriteria decision making mechanisms Documents, reports 2019-10-03 19:01:14
Planning test phase report Documents, reports 2019-10-03 19:01:14
9M technical & management Progress report Documents, reports 2019-10-03 19:01:14
Periodic TF and Innovation evaluation Report 2 Documents, reports 2019-10-03 19:01:14
Technology Forecasting Plan Documents, reports 2019-10-03 19:01:14
Periodic TF and Innovation evaluation Report 1 Documents, reports 2019-10-03 19:01:14
Dissemination Strategy Documents, reports 2019-10-03 19:01:14
Project Intranet Websites, patent fillings, videos etc. 2019-10-03 19:01:14
Risk Analysis & Management Plan Documents, reports 2019-10-03 19:01:14
Project Handbook Documents, reports 2019-10-03 19:01:14
18M technical & management Progress report Documents, reports 2019-10-03 19:01:14
Periodical Dissemination Report 1 Documents, reports 2019-10-03 19:01:14
Periodic Report 1 Documents, reports 2019-10-03 19:01:14
Periodic TF and Innovation evaluation Report 3 Documents, reports 2019-10-03 19:01:14
Periodical Dissemination Report 2 Documents, reports 2019-10-03 19:01:14
Periodic TF and Innovation evaluation Report 4 Documents, reports 2019-10-03 19:01:14
Periodic TF and Innovation evaluation Report 5 Documents, reports 2019-10-03 19:01:14
Prototype of the platform Demonstrators, pilots, prototypes 2019-10-03 19:01:14
Exploitation plan Documents, reports 2019-10-03 19:01:14
Prototype of the platform - REPORT Documents, reports 2019-10-03 19:01:14
Periodic Report 2 Documents, reports 2019-10-03 19:01:14
Operation manual of the LIQBIOPSENS system Documents, reports 2019-10-03 19:01:14
Final Project Report Documents, reports 2019-10-03 19:01:14
36M technical & management Progress report Documents, reports 2019-10-03 19:01:14
27M technical & management Progress report Documents, reports 2019-10-03 19:01:14
Continuous supply of disposable test cartridges to the rest of activities of LIQBIOPSENS project - REPORT Documents, reports 2019-10-03 19:01:14
Periodical Dissemination Report 3 Documents, reports 2019-10-03 19:01:14
Control Software Demonstrators, pilots, prototypes 2019-10-03 19:01:14
Validation Report Documents, reports 2019-10-03 19:01:14
Control Software - REPORT Documents, reports 2019-10-03 19:01:14

Take a look to the deliverables list in detail:  detailed list of Liqbiopsens deliverables.

 Publications

year authors and title journal last update
List of publications.
2018 Antonio Arnau, Hugh Ilyine
Liqbiopsens – Reliable Novel Liquid Biopsy technology for early detection of colorectal cancer – H2020
published pages: 49-51, ISSN: 2398-7073, DOI: 10.21820/23987073.2018.12.49
Impact 2018/12 2019-10-03
2017 Román Fernández, Pablo García, María García, José García, Yolanda Jiménez, Antonio Arnau
Design and Validation of a 150 MHz HFFQCM Sensor for Bio-Sensing Applications
published pages: 2057, ISSN: 1424-8220, DOI: 10.3390/s17092057
Sensors 17/9 2019-10-03
2017 Aristea Grammoustianou, George Papadakis, Electra Gizeli
Solid-Phase Isothermal DNA Amplification and Detection on Quartz Crystal Microbalance Using Liposomes and Dissipation Monitoring
published pages: 1-4, ISSN: 2475-1472, DOI: 10.1109/lsens.2017.2739803
IEEE Sensors Letters 1/5 2019-10-03

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The information about "LIQBIOPSENS" are provided by the European Opendata Portal: CORDIS opendata.

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