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Exploiting vortices to suppress dispersion and reach new separation power boundaries

Total Cost €


EC-Contrib. €






 EVODIS project word cloud

Explore the words cloud of the EVODIS project. It provides you a very rough idea of what is the project "EVODIS" about.

linked    electrodes    limitations    enhanced    whereby    differential    pursued    performance    chromatography    improvements    determined    ground    preparative    small    pressure    analyte    technique    anti    membrane    requirement    structure    tens    array    fluids    molecules    rate    reducing    heating    structures    predominantly    transfer    reactor    local    electroosmotic    achievement    components    analytical    surfaces    fabrication    separate    create    thousands    micron    arrays    prominent    mass    vortex    ever    transport    benefit    progress    chemical    direction    meet    diffusion    chromatographic    vortices    breaking    tools    viscous    incremental    longer    emulsification    interaction    revolutionize    requiring    giving    fashion    faster    macromolecules    relying    lateral    fouling    century    migration    strategy    tolerance    sub    limits    pace    depending    flow    intimately    matrices    microstructures    practical    accelerate    separation    ordered    bio    mixing    size    velocity    21st    unfortunately    packing    flows    implementing    anisotropic    satisfy    liquid    column    channels    proteomics    society   

Project "EVODIS" data sheet

The following table provides information about the project.


Organization address
address: PLEINLAAN 2
postcode: 1050

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Belgium [BE]
 Project website
 Total cost 1˙460˙687 €
 EC max contribution 1˙460˙687 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2015-STG
 Funding Scheme ERC-STG
 Starting year 2016
 Duration (year-month-day) from 2016-03-01   to  2021-02-28


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    VRIJE UNIVERSITEIT BRUSSEL BE (BRUSSEL) coordinator 1˙460˙687.00


 Project objective

The 21st century is expected to develop towards a society depending ever and ever more on (bio-)chemical measurements of fluids and matrices that are so complex they are well beyond the current analytical capabilities. Incremental improvements can no longer satisfy the current needs of e.g. the proteomics field, requiring the separation of tens of thousands of components. The pace of progress in these fields is therefore predominantly determined by that of analytical tools, whereby liquid chromatography is the most prominent technique to separate small molecules as well as macromolecules, based on differential interaction of each analyte with support structures giving it a unique migration velocity. To improve its performance, a faster transport between these structures needs to be generated. Unfortunately the commonly pursued strategy, relying on diffusion and reducing the structure size, has come to its limits due to practical limitations related to packing and fabrication of sub-micron support structures, pressure tolerance and viscous heating. A ground-breaking step to advance chromatographic performance to another level would be to accelerate mass transport in the lateral direction, beyond the rate of diffusion only. To meet this requirement, an array of microstructures and local electrodes can be defined to create lateral electroosmotic vortices in a pressure-driven column, aiming to accelerate the local mass transfer in an anisotropic fashion. The achievement of ordered arrays of vortices is intimately linked to this requirement, which is also of broader importance for mixing, anti-fouling of membrane and reactor surfaces, enhanced mass transfer in reactor channels, emulsification, etc. Understanding and implementing anisotropic vortex flows will therefore not only revolutionize analytical and preparative separation procedures, but will also be highly relevant in all flow systems that benefit from enhanced mass transfer.


year authors and title journal last update
List of publications.
2017 Shunta Futagami, Takeshi Hara, Heidi Ottevaere, Gino V. Baron, Gert Desmet, Wim De Malsche
Preparation and evaluation of mesoporous silica layers on radially elongated pillars
published pages: 234-241, ISSN: 0021-9673, DOI:
Journal of Chromatography A 1523 2019-10-09
2018 Christina Tiflidis, Wouter Olthuis, Jan Eijkel, Wim De Malsche
Continuous Flow Particle Focusing by AC-actuation
published pages: , ISSN: , DOI:
Twenty Second International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2018) - Conference proceedings 2019-10-08
2016 Takeshi Hara, Shunta Futagami, Sebastiaan Eeltink, Wim De Malsche, Gino V. Baron, Gert Desmet
Very High Efficiency Porous Silica Layer Open-Tubular Capillary Columns Produced via in-Column Sol–Gel Processing
published pages: 10158-10166, ISSN: 0003-2700, DOI: 10.1021/acs.analchem.6b02713
Analytical Chemistry 88/20 2019-06-19
2016 F. Haudin, M. Callewaert, W. De Malsche, A. De Wit
Influence of nonideal mixing properties on viscous fingering in micropillar array columns
published pages: all, ISSN: 2469-990X, DOI: 10.1103/physrevfluids.1.074001
Physical Review Fluids 1/7 2019-06-19
2018 Pierre Gelin, Iwona Ziemecka, Kris Pauwels, Marzena Krzek, Ozlem Sardan Sukas, Peter Tompa, Dominique Maes, Wim De Malsche
Growth and Separation of Crystals and Protein Aggregates in Acoustofluidics
published pages: , ISSN: , DOI:
22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2018) 2019-06-19

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The information about "EVODIS" are provided by the European Opendata Portal: CORDIS opendata.

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