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DRYNET SIGNED

Setting an interdisciplinary/sectorial/international research network to explore dry storage as an alternative strategy for cells/germplasm biobanking

Total Cost €

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EC-Contrib. €

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Partnership

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 DRYNET project word cloud

Explore the words cloud of the DRYNET project. It provides you a very rough idea of what is the project "DRYNET" about.

repository    block    molecular    expensive    water    diagnostic    insect    simplification    basis    transferable    summer    thailand    embryology    biology    international    pan    loaded    subtraction    sustainability    biobanking    strengthens    representing    xero    gametes    mechanical    biobank    mathematical    reversible    academia    math    currents    public    cryopreservation    plan    footprint    workshop    maintenance    practices    proteins    cells    ln    expertise    engineering    knowhow    carries    lay    hazardous    natural    tools    exponentially    competitiveness    sme    survival    multidisciplinary    purposes    empirical    japan    secondments    nitrogen    meeting    anhydrobiosis    academic    young    biobanks    induce    biodiversity    sectorial    primary    prospect    foresees    merges    pathogens    carbon    though    inter    economic    school    smes    facilities    theoretical    network    coherent    biophysical    career    disciplines    boosts    industry    storage    abundant    drying    nature    sharing    burden    strategy    ensures    guarantee    expressed    generate    academy    clinical    metabolism    liquid    preservation    shipping    drynet    embryogenesis    relies    scientists    outreaching    germplasm    cellular    protectants    skills    dry   

Project "DRYNET" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITA DEGLI STUDI DI TERAMO 

Organization address
address: VIA RENATO BALZARINI 1 3 5 7
city: TERAMO
postcode: 64100
website: www.unite.it

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Project website http://drynet.unite.it/
 Total cost 841˙500 €
 EC max contribution 765˙000 € (91%)
 Programme 1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
 Code Call H2020-MSCA-RISE-2016
 Funding Scheme MSCA-RISE
 Starting year 2017
 Duration (year-month-day) from 2017-03-01   to  2021-02-28

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITA DEGLI STUDI DI TERAMO IT (TERAMO) coordinator 238˙500.00
2    BIOTALENTUM TUDASFEJLESZTO KFT HU (GOEDOELLO) participant 171˙000.00
3    UNIVERSIDAD DE BURGOS ES (BURGOS) participant 148˙500.00
4    UNIVERSITA DEGLI STUDI DI CAGLIARI IT (CAGLIARI) participant 112˙500.00
5    UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA IT (MODENA) participant 63˙000.00
6    AVANTEA srl IT (Cremona) participant 27˙000.00
7    IMAGENE FR (PESSAC) participant 4˙500.00
8    BIOBANKS AND BIOMOLECULAR RESOURCESRESEARCH INFRASTRUCTURE CONSORTIUM(BBMRI-ERIC) AT (GRAZ) participant 0.00
9    CHULALONGKORN UNIVERSITY TH (BANGKOK) partner 0.00
10    NATIONAL AGRICULTURE AND FOOD RESEARCH ORGANIZATION JP (TSUKUBA IBARAKI) partner 0.00

Map

 Project objective

The number of biobanks for diagnostic/clinical/biodiversity preservation purposes is increasing exponentially, representing an economic burden for the EU. Cryopreservation (Liquid Nitrogen LN) is the only cells/gametes long-term repository method. LN storage is expensive though, requires dedicated facilities, is hazardous, carries pathogens and has high carbon footprint. DRYNET objective is to set an inter-sectorial/multidisciplinary/international network between EU academic (5), SME (3), the EU pan-Biobank, and international partners (Japan/Thailand), with the aim of sharing knowhow & expertise to lay down the theoretical and early empirical basis for the dry storage of cells/germplasm. DRYNET merges the partner’s expertise, theoretical/ biophysical/ mathematical modelling, cellular/ molecular/ insect biology, embryology, mechanical engineering into a coherent approach towards dry storage of cells/germplasm. International/inter-sectorial secondments, with meeting/workshop/summer school will be primary tools to implement our strategy for biobanking. Outreaching activities will guarantee public awareness of the project. DRYNET’s relies on water subtraction to induce a reversible block of metabolism, a survival strategy available in nature (anhydrobiosis). The work plan foresees the exploitation of natural xero-protectants (Late Embryogenesis Abundant proteins), loaded/expressed in gametes/cells, before drying. The best drying approaches, supported by theoretical/biophysical/math modelling, will be implemented by SMEs/academy partners. DRYNET will bring a simplification of currents practices, with cost and carbon footprint reduction, for the maintenance/shipping of biobanks. DRYNET will generate young scientists with transferable skills, ensuring career prospect in academia/industry. DRYNET strengthens the international/sectorial network between different disciplines, ensures long-term sustainability of the project, and boosts European competitiveness in biobanking.

 Publications

year authors and title journal last update
List of publications.
2019 Debora Agata Anzalone, Luca Palazzese, Domenico Iuso, Giuseppe Martino, Pasqualino Loi
Corrigendum to “Freeze-dried spermatozoa: An alternative biobanking option for endangered species” [Anim. Reprod. Sci. 190C (2018) 85–93]
published pages: 96, ISSN: 0378-4320, DOI: 10.1016/j.anireprosci.2018.12.008
Animal Reproduction Science 202 2020-04-15
2020 Joseph Saragusty, Debora Agata Anzalone, Luca Palazzese, Amir Arav, Pasquale Patrizio, Jaime Gosálvez, Pasqualino Loi
Dry biobanking as a conservation tool in the Anthropocene
published pages: , ISSN: 0093-691X, DOI: 10.1016/j.theriogenology.2020.01.022
Theriogenology 2020-04-15
2019 Elisa Casula, Gabriele Traversari, Sarah Fadda, Oleksiy V. Klymenko, Cleo Kontoravdi, Alberto Cincotti
Modelling the osmotic behaviour of human mesenchymal stem cells
published pages: 107296, ISSN: 1369-703X, DOI: 10.1016/j.bej.2019.107296
Biochemical Engineering Journal 151 2020-04-15
2019 Marta Czernik, Debora A. Anzalone, Luca Palazzese, Mami Oikawa, Pasqualino Loi
Somatic cell nuclear transfer: failures, successes and the challenges ahead
published pages: 123-130, ISSN: 0214-6282, DOI: 10.1387/ijdb.180324mc
The International Journal of Developmental Biology 63/3-4-5 2020-04-07
2018 Takahiro G. Yamada, Yoshitaka Suetsugu, Ruslan Deviatiiarov, Oleg Gusev, Richard Cornette, Alexander Nesmelov, Noriko Hiroi, Takahiro Kikawada, Akira Funahashi
Transcriptome analysis of the anhydrobiotic cell line Pv11 infers the mechanism of desiccation tolerance and recovery
published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-018-36124-6
Scientific Reports 8/1 2020-01-20
2018 Luca PALAZZESE, Jaime GOSÁLVEZ, Debora A. ANZALONE, Pasqualino LOI, Joseph SARAGUSTY
DNA fragmentation in epididymal freeze-dried ram spermatozoa impairs embryo development
published pages: 393-400, ISSN: 0916-8818, DOI: 10.1262/jrd.2018-033
Journal of Reproduction and Development 64/5 2020-01-20
2018 Luca PALAZZESE, Jaime GOSÁLVEZ, Debora A. ANZALONE, Pasqualino LOI, Joseph SARAGUSTY
DNA fragmentation in epididymal freeze-dried ram spermatozoa impairs embryo development
published pages: 393-400, ISSN: 0916-8818, DOI: 10.1262/jrd.2018-033
Journal of Reproduction and Development 64/5 2020-01-20
2018 Debora Agata Anzalone, Luca Palazzese, Domenico Iuso, Giuseppe Martino, Pasqualino Loi
Freeze-dried spermatozoa: An alternative biobanking option for endangered species
published pages: 85-93, ISSN: 0378-4320, DOI: 10.1016/j.anireprosci.2018.01.010
Animal Reproduction Science 190 2020-01-20
2018 Luca Palazzese, Marta Czernik, Domenico Iuso, Paola Toschi, Pasqualino Loi
Nuclear quiescence and histone hyper-acetylation jointly improve protamine-mediated nuclear remodeling in sheep fibroblasts
published pages: e0193954, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0193954
PLOS ONE 13/3 2020-01-20

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