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DRYNET SIGNED

Setting an interdisciplinary/sectorial/international research network to explore dry storage as an alternative strategy for cells/germplasm biobanking

Total Cost €

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EC-Contrib. €

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Partnership

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 DRYNET project word cloud

Explore the words cloud of the DRYNET project. It provides you a very rough idea of what is the project "DRYNET" about.

guarantee    cellular    cryopreservation    multidisciplinary    career    biobanking    clinical    though    insect    academy    block    academia    survival    inter    sectorial    public    coherent    gametes    biobank    xero    induce    sharing    basis    hazardous    mathematical    theoretical    anhydrobiosis    maintenance    plan    tools    young    secondments    expensive    sustainability    lay    engineering    footprint    international    relies    competitiveness    subtraction    reversible    boosts    expressed    industry    nitrogen    protectants    diagnostic    loaded    workshop    biodiversity    molecular    knowhow    empirical    purposes    cells    scientists    math    facilities    carbon    shipping    exponentially    mechanical    prospect    expertise    simplification    representing    transferable    embryology    repository    water    strengthens    sme    storage    biobanks    currents    pan    preservation    academic    biophysical    nature    drynet    practices    meeting    dry    smes    embryogenesis    germplasm    merges    ln    primary    pathogens    ensures    natural    liquid    carries    economic    school    biology    generate    outreaching    burden    metabolism    network    skills    summer    strategy    thailand    drying    proteins    abundant    foresees    disciplines    japan   

Project "DRYNET" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITA DEGLI STUDI DI TERAMO 

Organization address
address: VIA RENATO BALZARINI 1 3 5 7
city: TERAMO
postcode: 64100
website: www.unite.it

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Project website http://drynet.unite.it/
 Total cost 841˙500 €
 EC max contribution 765˙000 € (91%)
 Programme 1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
 Code Call H2020-MSCA-RISE-2016
 Funding Scheme MSCA-RISE
 Starting year 2017
 Duration (year-month-day) from 2017-03-01   to  2021-02-28

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITA DEGLI STUDI DI TERAMO IT (TERAMO) coordinator 238˙500.00
2    BIOTALENTUM TUDASFEJLESZTO KFT HU (GOEDOELLO) participant 171˙000.00
3    UNIVERSIDAD DE BURGOS ES (BURGOS) participant 148˙500.00
4    UNIVERSITA DEGLI STUDI DI CAGLIARI IT (CAGLIARI) participant 112˙500.00
5    UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA IT (MODENA) participant 63˙000.00
6    AVANTEA srl IT (Cremona) participant 27˙000.00
7    IMAGENE FR (PESSAC) participant 4˙500.00
8    BIOBANKS AND BIOMOLECULAR RESOURCESRESEARCH INFRASTRUCTURE CONSORTIUM(BBMRI-ERIC) AT (GRAZ) participant 0.00
9    CHULALONGKORN UNIVERSITY TH (BANGKOK) partner 0.00
10    NATIONAL AGRICULTURE AND FOOD RESEARCH ORGANIZATION JP (TSUKUBA IBARAKI) partner 0.00

Map

 Project objective

The number of biobanks for diagnostic/clinical/biodiversity preservation purposes is increasing exponentially, representing an economic burden for the EU. Cryopreservation (Liquid Nitrogen LN) is the only cells/gametes long-term repository method. LN storage is expensive though, requires dedicated facilities, is hazardous, carries pathogens and has high carbon footprint. DRYNET objective is to set an inter-sectorial/multidisciplinary/international network between EU academic (5), SME (3), the EU pan-Biobank, and international partners (Japan/Thailand), with the aim of sharing knowhow & expertise to lay down the theoretical and early empirical basis for the dry storage of cells/germplasm. DRYNET merges the partner’s expertise, theoretical/ biophysical/ mathematical modelling, cellular/ molecular/ insect biology, embryology, mechanical engineering into a coherent approach towards dry storage of cells/germplasm. International/inter-sectorial secondments, with meeting/workshop/summer school will be primary tools to implement our strategy for biobanking. Outreaching activities will guarantee public awareness of the project. DRYNET’s relies on water subtraction to induce a reversible block of metabolism, a survival strategy available in nature (anhydrobiosis). The work plan foresees the exploitation of natural xero-protectants (Late Embryogenesis Abundant proteins), loaded/expressed in gametes/cells, before drying. The best drying approaches, supported by theoretical/biophysical/math modelling, will be implemented by SMEs/academy partners. DRYNET will bring a simplification of currents practices, with cost and carbon footprint reduction, for the maintenance/shipping of biobanks. DRYNET will generate young scientists with transferable skills, ensuring career prospect in academia/industry. DRYNET strengthens the international/sectorial network between different disciplines, ensures long-term sustainability of the project, and boosts European competitiveness in biobanking.

 Publications

year authors and title journal last update
List of publications.
2019 Debora Agata Anzalone, Luca Palazzese, Domenico Iuso, Giuseppe Martino, Pasqualino Loi
Corrigendum to “Freeze-dried spermatozoa: An alternative biobanking option for endangered species” [Anim. Reprod. Sci. 190C (2018) 85–93]
published pages: 96, ISSN: 0378-4320, DOI: 10.1016/j.anireprosci.2018.12.008
Animal Reproduction Science 202 2020-04-15
2020 Joseph Saragusty, Debora Agata Anzalone, Luca Palazzese, Amir Arav, Pasquale Patrizio, Jaime Gosálvez, Pasqualino Loi
Dry biobanking as a conservation tool in the Anthropocene
published pages: , ISSN: 0093-691X, DOI: 10.1016/j.theriogenology.2020.01.022
Theriogenology 2020-04-15
2019 Elisa Casula, Gabriele Traversari, Sarah Fadda, Oleksiy V. Klymenko, Cleo Kontoravdi, Alberto Cincotti
Modelling the osmotic behaviour of human mesenchymal stem cells
published pages: 107296, ISSN: 1369-703X, DOI: 10.1016/j.bej.2019.107296
Biochemical Engineering Journal 151 2020-04-15
2019 Marta Czernik, Debora A. Anzalone, Luca Palazzese, Mami Oikawa, Pasqualino Loi
Somatic cell nuclear transfer: failures, successes and the challenges ahead
published pages: 123-130, ISSN: 0214-6282, DOI: 10.1387/ijdb.180324mc
The International Journal of Developmental Biology 63/3-4-5 2020-04-07
2018 Takahiro G. Yamada, Yoshitaka Suetsugu, Ruslan Deviatiiarov, Oleg Gusev, Richard Cornette, Alexander Nesmelov, Noriko Hiroi, Takahiro Kikawada, Akira Funahashi
Transcriptome analysis of the anhydrobiotic cell line Pv11 infers the mechanism of desiccation tolerance and recovery
published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-018-36124-6
Scientific Reports 8/1 2020-01-20
2018 Luca PALAZZESE, Jaime GOSÁLVEZ, Debora A. ANZALONE, Pasqualino LOI, Joseph SARAGUSTY
DNA fragmentation in epididymal freeze-dried ram spermatozoa impairs embryo development
published pages: 393-400, ISSN: 0916-8818, DOI: 10.1262/jrd.2018-033
Journal of Reproduction and Development 64/5 2020-01-20
2018 Luca PALAZZESE, Jaime GOSÁLVEZ, Debora A. ANZALONE, Pasqualino LOI, Joseph SARAGUSTY
DNA fragmentation in epididymal freeze-dried ram spermatozoa impairs embryo development
published pages: 393-400, ISSN: 0916-8818, DOI: 10.1262/jrd.2018-033
Journal of Reproduction and Development 64/5 2020-01-20
2018 Debora Agata Anzalone, Luca Palazzese, Domenico Iuso, Giuseppe Martino, Pasqualino Loi
Freeze-dried spermatozoa: An alternative biobanking option for endangered species
published pages: 85-93, ISSN: 0378-4320, DOI: 10.1016/j.anireprosci.2018.01.010
Animal Reproduction Science 190 2020-01-20
2018 Luca Palazzese, Marta Czernik, Domenico Iuso, Paola Toschi, Pasqualino Loi
Nuclear quiescence and histone hyper-acetylation jointly improve protamine-mediated nuclear remodeling in sheep fibroblasts
published pages: e0193954, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0193954
PLOS ONE 13/3 2020-01-20

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