Explore the words cloud of the BioMNP project. It provides you a very rough idea of what is the project "BioMNP" about.
The following table provides information about the project.
UNIVERSITA DEGLI STUDI DI GENOVA
|Coordinator Country||Italy [IT]|
|Total cost||1˙131˙250 €|
|EC max contribution||1˙131˙250 € (100%)|
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
|Duration (year-month-day)||from 2016-04-01 to 2021-03-31|
Take a look of project's partnership.
|1||UNIVERSITA DEGLI STUDI DI GENOVA||IT (GENOVA)||coordinator||1˙131˙250.00|
The BioMNP objective is the molecular-level understanding of the interactions between surface functionalized metal nanoparticles and biological membranes, by means of cutting-edge computational techniques and new molecular models. Metal nanoparticles (NP) play more and more important roles in pharmaceutical and medical technology as diagnostic or therapeutic devices. Metal NPs can nowadays be engineered in a multitude of shapes, sizes and compositions, and they can be decorated with an almost infinite variety of functionalities. Despite such technological advances, there is still poor understanding of the molecular processes that drive the interactions of metal NPs with cells. Cell membranes are the first barrier encountered by NPs entering living organisms. The understanding and control of the interaction of nanoparticles with biological membranes is therefore of paramount importance to understand the molecular basis of the NP biological effects. BioMNP will go beyond the state of the art by rationalizing the complex interplay of NP size, composition, functionalization and aggregation state during the interaction with model biomembranes. Membranes, in turn, will be modelled at an increasing level of complexity in terms of lipid composition and phase. BioMNP will rely on cutting-edge simulation techniques and facilities, and develop new coarse-grained models grounded on finer-level atomistic simulations, to study the NP-membrane interactions on an extremely large range of length and time scales. BioMNP will benefit from important and complementary experimental collaborations, will propose interpretations of the available experimental data and make predictions to guide the design of functional, non-toxic metal nanoparticles for biomedical applications. BioMNP aims at answering fundamental questions at the crossroads of physics, biology and chemistry. Its results will have an impact on nanomedicine, toxicology, nanotechnology and material sciences.
|year||authors and title||journal||last update|
S Salassi, F Simonelli, A Bartocci, G Rossi
A Martini coarse-grained model of the calcein fluorescent dye
published pages: 384002, ISSN: 0022-3727, DOI: 10.1088/1361-6463/aad4b8
|Journal of Physics D: Applied Physics 51/38||2019-10-29|
Fabian Grunewald, Giulia Rossi, Alex H. de Vries, Siewert J. Marrink, Luca Monticelli
Transferable MARTINI Model of Poly(ethylene Oxide)
published pages: 7436-7449, ISSN: 1520-6106, DOI: 10.1021/acs.jpcb.8b04760
|The Journal of Physical Chemistry B 122/29||2019-10-29|
Sebastian Salassi, Federica Simonelli, Davide Bochicchio, Riccardo Ferrando, Giulia Rossi
Au Nanoparticles in Lipid Bilayers: A Comparison between Atomistic and Coarse-Grained Models
published pages: 10927-10935, ISSN: 1932-7447, DOI: 10.1021/acs.jpcc.6b12148
|The Journal of Physical Chemistry C 121/20||2019-09-04|
Andrea Torchi, Federica Simonelli, Riccardo Ferrando, Giulia Rossi
Local Enhancement of Lipid Membrane Permeability Induced by Irradiated Gold Nanoparticles
published pages: , ISSN: 1936-0851, DOI: 10.1021/acsnano.7b06690
D. Bochicchio, E. Panizon, L. Monticelli, G. Rossi
Interaction of hydrophobic polymers with model lipid bilayers
published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-017-06668-0
|Scientific Reports 7/1||2019-09-04|
Federica Simonelli, Giulia Rossi, Luca Monticelli
Role of Ligand Conformation on Nanoparticleâ€“Protein Interactions
published pages: 1764-1769, ISSN: 1520-6106, DOI: 10.1021/acs.jpcb.8b11204
|The Journal of Physical Chemistry B 123/8||2019-09-04|
Sebastian Salassi, Ester Canepa, Riccardo Ferrando, Giulia Rossi
Anionic nanoparticle-lipid membrane interactions: the protonation of anionic ligands at the membrane surface reduces membrane disruption
published pages: 13992-13997, ISSN: 2046-2069, DOI: 10.1039/c9ra02462j
|RSC Advances 9/25||2019-09-04|
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "BIOMNP" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (firstname.lastname@example.org) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "BIOMNP" are provided by the European Opendata Portal: CORDIS opendata.
Comprehensive anatomical, genetic and functional identification of cerebellar nuclei neurons and their roles in sensorimotor tasksRead More
Mount Athos in Medieval Eastern Mediterranean Society: Contextualizing the History of a Monastic Republic (ca. 850-1550)Read More
The Neurological Basis of the Magnetic SenseRead More