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MAST4HEALTH SIGNED

Mastiha treatment for healthy obese with NAFLD diagnosis (MAST4HEALTH).

Total Cost €

0

EC-Contrib. €

0

Partnership

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Project "MAST4HEALTH" data sheet

The following table provides information about the project.

Coordinator
CHAROKOPEIO PANEPISTIMIO 

Organization address
address: ELEFTHERIOU VENIZELOU 70
city: ATHINA
postcode: 17671
website: www.hua.gr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Greece [EL]
 Project website http://www.mast4health.eu/en/
 Total cost 2˙124˙000 €
 EC max contribution 2˙124˙000 € (100%)
 Programme 1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
 Code Call H2020-MSCA-RISE-2015
 Funding Scheme MSCA-RISE
 Starting year 2016
 Duration (year-month-day) from 2016-03-01   to  2020-02-29

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CHAROKOPEIO PANEPISTIMIO EL (ATHINA) coordinator 441˙000.00
2    ENOSIS MASTICHOPARAGOGON CHIOU EL (CHIOS) participant 297˙000.00
3    QUEEN MARY UNIVERSITY OF LONDON UK (LONDON) participant 162˙000.00
4    BIOTECH VANA SL ES (PATERNA (VALENCIA)) participant 157˙500.00
5    PERSPECTUM LTD UK (OXFORD) participant 157˙500.00
6    Randox Laboratories Ltd UK (Crumlin) participant 153˙000.00
7    INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE FR (PARIS) participant 135˙000.00
8    CONSIGLIO NAZIONALE DELLE RICERCHE IT (ROMA) participant 121˙500.00
9    FUNDACION PARA EL FOMENTO DE LA INVESTIGACION SANITARIA Y BIOMEDICA DE LA COMUNITAT VALENCIANA ES (VALENCIA) participant 117˙000.00
10    MARASCIO FERNANDO IT (CATANZARO) participant 108˙000.00
11    Univerzitet u Novom Sadu - Medicinski fakultet RS (Novi Sad) participant 108˙000.00
12    SANOFI-AVENTIS DEUTSCHLAND GMBH DE (FRANKFURT AM MAIN) participant 81˙000.00
13    UNIVERSITA DEGLI STUDI DI MILANO IT (MILANO) participant 63˙000.00
14    UNIVERZITET U ISTOCNOM SARAJEVU BA (ISTOCNO SARAJEVO) participant 13˙500.00
15    FONDAZIONE IRCCS CA' GRANDA - OSPEDALE MAGGIORE POLICLINICO IT (MILANO) participant 9˙000.00

Map

 Project objective

MAST4HEALTH is set on the concept of a multidisciplinary approach to assess a non-pharmacological intervention for managing NAFLD/NASH, one of the most common complications of obesity and diabetes mellitus in Western populations affecting approximately 50% of diabetics and 76% of obese patients. Because of limitations in current NAFLD treatment therapies, many new efforts focus on exploring non-pharmacologic means for managing the disease and in particular through dietary substances or bioactive phytochemicals in fruits, vegetables, and plants or their products. MAST4HEALTH aims at exploring the effect of Mastiha, a natural product of Greece which was recently shown to possess antioxidant/anti-inflammatory and lipid lowering properties. We designed a multicenter randomized double blind placebo controlled (parallel arm) clinical trial to test the effectiveness of Mastiha supplement as new non-pharmacologic strategy for NAFLD/NASH treatment. MAST4HEALTH will explore gene-diet interactions, more specifically the potential personalized activity of the Mastiha, and correlate genetic and epigenetic markers with metabolomic and intestinal microbiota profiles pre- and post-intervention. The effectiveness of the proposed intervention will be evaluated via clinical and laboratory markers of the disease. To this end, MAST4HEALTH will train a number of researchers and PhD students in multidisciplinary approaches of this survey. MAST4HEALTH is expected to build and enhance cooperation among partners meanwhile strengthening the interaction between our academic and non-academic sectors

 Deliverables

List of deliverables.
Organization of all Meetings Other 2020-03-11 12:59:20
Acceptance for publication of manuscripts Documents, reports 2020-03-11 12:59:20
Abstract submission to conferences Other 2020-03-11 12:59:20
E-newsletter publication Websites, patent fillings, videos etc. 2020-03-11 12:59:20
Web page creation Websites, patent fillings, videos etc. 2020-03-11 12:59:20
Progress report P1 Other 2020-03-11 12:59:20
Public engagement and outreach plan Other 2020-03-11 12:59:20

Take a look to the deliverables list in detail:  detailed list of MAST4HEALTH deliverables.

 Publications

year authors and title journal last update
List of publications.
2019 Aimo Kannt, Efstathia Papada, Claire Kammermeier, Giuseppe D\'Auria, Nuria Jiménez‐Hernández, Martin Stephan, Uwe Schwahn, Andreas Nygaard Madsen, Mette Viberg Østergaard, George Dedoussis, M. Pilar Francino
Mastiha ( Pistacia lentiscus ) Improves Gut Microbiota Diversity, Hepatic Steatosis, and Disease Activity in a Biopsy‐Confirmed Mouse Model of Advanced Non‐Alcoholic Steatohepatitis and Fibrosis
published pages: 1900927, ISSN: 1613-4125, DOI: 10.1002/mnfr.201900927
Molecular Nutrition & Food Research 63/24 2020-03-11

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The information about "MAST4HEALTH" are provided by the European Opendata Portal: CORDIS opendata.

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