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microMAGNETOFLUIDICS

3D-printed magnetic microfluidics for applications in life sciences

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EC-Contrib. €

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Partnership

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Project "microMAGNETOFLUIDICS" data sheet

The following table provides information about the project.

Coordinator
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH 

Organization address
address: Raemistrasse 101
city: ZUERICH
postcode: 8092
website: https://www.ethz.ch/de.html

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Project website https://micromagnetofluidics.eu/
 Total cost 187˙419 €
 EC max contribution 187˙419 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-06-01   to  2018-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH CH (ZUERICH) coordinator 187˙419.00

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 Project objective

The field of microfluidics is providing answers to several key questions in biology. Specifically, microfluidic single-cell analysis yields important insights into the heterogeneity of cells that is crucial for cancer research, regenerative medicine and drug development. Microfluidics has also emerged as a powerful tool to study single bacteria and to address questions concerning antibiotic persistence and the role of the microbiome in protecting against modern plagues such as cancer, autoimmune diseases and obesity. Despite its great potential, microfluidic technologies have not been widely adopted in mainstream biomedical research since they require a great deal of external equipment, which is often difficult to operate by untrained personnel. The aim of this proposal is to simplify fluid handling and single-cell studies by developing a microfluidic device that includes magnetic microvalves. These microvalves can be wirelessly actuated to generate compartments and isolate single cells. The magnetic microvalves will be integrated by means of a very recently available lithographic tool based on two-photon polymerization (2PP) with sub-diffraction limit resolution, which enables the fabrication of polymer-based 3D micro- and nano-architectures. The microMAGNETOFLUIDICS project is strongly interdisciplinary in nature where physics, materials science, and biology are strongly intertwined. The innovative character of this proposal is unprecedented since no previous studies have been reported on 3D-printed magnetic microvalves operating within a microfluidic channel. The topic of the project is timely because it promotes the use of microfluidics among biologists and bacteriologists for decrypting cellular mechanisms at a single-cell level.

 Publications

year authors and title journal last update
List of publications.
2018 George Chatzipirpiridis, Carmela de Marco, Eva Pellicer, Olgaç Ergeneman, Jordi Sort, Bradley J. Nelson, Salvador Pané
Template-Assisted Electroforming of Fully Semi-Hard-Magnetic Helical Microactuators
published pages: 1800179, ISSN: 1438-1656, DOI: 10.1002/adem.201800179
Advanced Engineering Materials 2019-06-13
2018 Xiaopu Wang, Chengzhi Hu, Lukas Schurz, Carmela De Marco, Xiangzhong Chen, Salvador Pané, Bradley J. Nelson
Surface-Chemistry-Mediated Control of Individual Magnetic Helical Microswimmers in a Swarm
published pages: 6210-6217, ISSN: 1936-0851, DOI: 10.1021/acsnano.8b02907
ACS Nano 12/6 2019-06-13
2018 Carmela de Marco, Salvador Pané, Bradley J. Nelson
4D printing and robotics
published pages: eaau0449, ISSN: 2470-9476, DOI: 10.1126/scirobotics.aau0449
Science Robotics 3/18 2019-06-13
2018 Xiang-Zhong Chen, Bumjin Jang, Daniel Ahmed, Chengzhi Hu, Carmela De Marco, Marcus Hoop, Fajer Mushtaq, Bradley J. Nelson, Salvador Pané
Small-Scale Machines Driven by External Power Sources
published pages: 1705061, ISSN: 0935-9648, DOI: 10.1002/adma.201705061
Advanced Materials 30/15 2019-06-13

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The information about "MICROMAGNETOFLUIDICS" are provided by the European Opendata Portal: CORDIS opendata.

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