Opendata, web and dolomites

DASCE TERMINATED

Dissecting specific amygdala-striatal circuits for exploration

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 DASCE project word cloud

Explore the words cloud of the DASCE project. It provides you a very rough idea of what is the project "DASCE" about.

behavioral    surroundings    technique    variability    planning    brain    striatal    projection    fine    exploratory    amygdala    encoding    moving    emotional    specificity    actions    intricate    functionally    dorso    collaborative    combination    multiple    unpredictable    beneficial    calcium    mammals    connected    unfamiliar    evolution    overcome    nature    learned    variety    mice    behavior    elusive    neuronal    neurons    caused    imaging    implication    emotions    circumstances    reveal    explore    anxiety    survival    depression    uncover    innate    causally    gained    exact    striatum    multidisciplinary    cure    behaviors    compartment    experiences    unknown    optogenetic    cell    techniques    exploring    area    mechanism    disorders    post    hypothesized    familiar    starting    progression    medial    computational    projecting    classes    ensembles    dependent    gain    environment    employ    strategies    circuitries    animal    animals    projections    psychiatric    directed    dictated    types   

Project "DASCE" data sheet

The following table provides information about the project.

Coordinator
FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD 

Organization address
address: AVENIDA BRASILIA, CENTRO DE INVESTIGACAO DA FUNDACAO CHAMPALIMAUD
city: LISBOA
postcode: 1400-038
website: http://fchampalimaud.org/

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Portugal [PT]
 Total cost 148˙635 €
 EC max contribution 148˙635 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2017
 Duration (year-month-day) from 2017-09-01   to  2019-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD PT (LISBOA) coordinator 148˙635.00

Map

 Project objective

Survival and adaptation are dependent on an animal's ability to gain novel information in unfamiliar surroundings. Similar to other animal classes, mammals must use a variety of innate and learned exploratory strategies that are dictated by unpredictable or unknown circumstances. As the combination of emotional processes and planning of complex actions are essential for the development of such strategies, it can be hypothesized that strongly connected brain areas involved in emotions (the amygdala) and goal-directed behaviors (the dorso-medial striatum) have an implication on exploratory behavior. The intricate neuronal nature and brain area specificity in the controlling of such strategies, however, remain elusive. In order to functionally uncover the role of specific amygdala-striatal long-range projections in freely-exploring mice, our collaborative study will adopt a multidisciplinary approach by a) developing a multiple-compartment behavioral task to study the exact evolution of exploratory strategies in a novel environment starting from a familiar one, b) examining the neuronal encoding of amygdala-striatal projecting neurons during exploratory progression using a novel calcium imaging technique in freely-moving animals, and c) causally relating the role of pre- and post- neuronal ensembles to exploratory strategies applying a projection-specific optogenetic approach. Furthermore, the proposed project will employ state-of -the-art techniques to reveal the fine computational mechanism used by animals to explore their surroundings and to determine the neuronal encoding specific to brain-, cell- and projection-types. Our research will be beneficial not only for understanding the role of defined circuitries in behavioral variability caused by unpredictable circumstances and the ability to overcome these through the knowledge gained from past experiences, but also for the finding of a cure for complex psychiatric disorders including anxiety and depression.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "DASCE" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "DASCE" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

REMAKIN (2019)

REstoring myocardial repair capacity via the modulation of MAcrophage-mediated cytoKINe secretion.

Read More  

SingleCellAI (2019)

Deep-learning models of CRISPR-engineered cells define a rulebook of cellular transdifferentiation

Read More  

WiseWomen (2020)

Wise Women: Beliefs and Networks of Female Spiritual Figures in Central European Vernacular Religion

Read More  
lastchecktime (2021-06-13 10:17:03) correctly updated