Opendata, web and dolomites

AS-ABA SIGNED

Alternative splicing and SR proteins in ABA-mediated plant stress responses

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 AS-ABA project word cloud

Explore the words cloud of the AS-ABA project. It provides you a very rough idea of what is the project "AS-ABA" about.

suggests    binding    plant    rip    mechanisms    pave    arabidopsis    biochemical    immunoprecipitation    transcriptome    expressing    serine    revealing    tagged    altered    localization    splicing    regions    largely    phytohormone    protein    mechanism    acid    regulated    of    plants    subcellular    proteome    significance    proteins    gene    six    levels    genome    version    unfavorable    alternative    efficient    mounting    environmental    eukaryotes    causes    hormonal    sequencing    salinity    genes    gain    reverse    mode    generation    strategies    arginine    unknown    regulating    flexible    aba    stress    cope    technologies    central    genetics    regulation    sr    play    worldwide    mechanistic    relevance    mediated    tolerance    abscisic    implicated    physiological    transcripts    rna    combination    drought    productivity    molecular    hormone    expanding    world    diversity    expression    action    crop    brief    pervasive    abiotic    underlying    posttranscriptional    roles    plays    discovering    seq    functional   

Project "AS-ABA" data sheet

The following table provides information about the project.

Coordinator
FUNDACAO CALOUSTE GULBENKIAN 

Organization address
address: AVENIDA BERNA 45
city: LISBOA
postcode: 1000
website: www.igc.gulbenkian.pt

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Portugal [PT]
 Project website http://www.igc.gulbenkian.pt/pduque
 Total cost 148˙635 €
 EC max contribution 148˙635 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2017
 Duration (year-month-day) from 2017-09-01   to  2019-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    FUNDACAO CALOUSTE GULBENKIAN PT (LISBOA) coordinator 148˙635.00

Map

 Project objective

Abscisic acid (ABA), the major plant stress hormone, plays a crucial role in the response to the most pervasive causes of loss of crop productivity worldwide, including drought and high salinity. Serine/arginine-rich (SR) proteins are RNA-binding proteins that play crucial roles in the regulation of alternative splicing (AS), a key posttranscriptional mechanism for expanding proteome diversity and a flexible means of regulating gene expression in higher eukaryotes. While its functional relevance in plants remains largely unknown, mounting evidence suggests a central role for AS in the response to abiotic stress, in particular by targeting the ABA hormonal pathway. Using gene expression analyses, subcellular localization studies and reverse genetics approaches, this project will investigate the functional significance of six ABA-regulated Arabidopsis SR genes in stress responses mediated by the ABA phytohormone. To gain mechanistic insight into the mode of action of the SR proteins implicated in the ABA pathway, the physiological transcripts targeted by these splicing factors to achieve plant stress tolerance will be identified using a combination of genome-wide and biochemical approaches. In brief, next-generation sequencing technologies will be applied to whole transcriptome analysis (RNA-seq) of plants with altered levels of an SR protein and to RNA immunoprecipitation (RIP-seq) in plants expressing a tagged version of the SR protein. In discovering new plant genes that determine the ability to cope with unfavorable environmental conditions and by revealing the molecular mechanisms underlying their mode of action, this work will pave the way for the development of new efficient strategies to improve crop productivity in specific world regions.

 Publications

year authors and title journal last update
List of publications.
2018 Tom Laloum, Guiomar Martín, Paula Duque
Alternative Splicing Control of Abiotic Stress Responses
published pages: 140-150, ISSN: 1360-1385, DOI: 10.1016/j.tplants.2017.09.019
Trends in Plant Science 23/2 2019-10-31

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "AS-ABA" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "AS-ABA" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

ALCO-ADO (2019)

Unveiling the alcohol-dependent alterations in local dendritic translation of mRNAs in the prefrontal cortex during adolescence

Read More  

FED (2019)

Feeding, Educating, Dieting: a Transnational Approach to Nutrition Discourses in Children’s Narratives (Britain and Italy, 1850-1900)

Read More  

COMLIB (2019)

Communists into Liberals: The Transformation and Demise of the Left as Precursor to the Illiberal Turn in Poland

Read More