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GENEVA SIGNED

Unravelling how GENEtic VAriation in attentional control contributes to working memory capacity

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 GENEVA project word cloud

Explore the words cloud of the GENEVA project. It provides you a very rough idea of what is the project "GENEVA" about.

influences    attentional    underlying    techniques    endophenotypes    skills    shed    predominant    markers    working    temporarily    diseases    genes    molecular    career    frontier    mind    correlates    erps    settings    limited    priorities    precisely    behavioural    subject    explore    performance    proposes    phenotypes    dat1    delve    intellectual    biological    efficient    personalized    optimal    genetics    plan    light    maintenance    symptom    combination    negotiates    encoding    mobility    dopamine    store    cutting    neural    turn    health    fellow    acquire    underpinning    everyday    cognition    influenced    genotypes    eeg    influence    hypothesis    event    wm    complementary    neurological    constraining    mental    considerable    neuroimaging    mechanisms    remembering    fall    storage    map    alleles    indicates    position    training    employed    oscillations    maturity    society    professional    life    memory    electroencephalography    shift    transferable    experimental    potentials    deficits    capacity    optimize    interplay    comt    scientific    modulation    broad    edge   

Project "GENEVA" data sheet

The following table provides information about the project.

Coordinator
THE CYPRUS FOUNDATION FOR MUSCULAR DYSTROPHY RESEARCH 

Organization address
address: International Airport Avenue 6
city: AYIOS DOMETIOS
postcode: 1683
website: www.cing.ac.cy

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Cyprus [CY]
 Project website https://www.andriashimi.com/geneva
 Total cost 163˙648 €
 EC max contribution 163˙648 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-07-01   to  2018-06-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE CYPRUS FOUNDATION FOR MUSCULAR DYSTROPHY RESEARCH CY (AYIOS DOMETIOS) coordinator 163˙648.00

Map

 Project objective

Working memory (WM) capacity, the ability to temporarily store information in mind, is especially important to a broad range of intellectual abilities and for optimal performance in everyday life settings. However, WM capacity is highly limited, which necessitates determining the factors that optimize/constrain efficient WM storage and remembering. To this end, new behavioural and neuroimaging evidence indicates that WM performance is influenced by attentional control. However, precisely how attention influences WM is not yet fully understood. Here, the applicant proposes to test the hypothesis that specific alleles in two dopamine-related genes, DAT1 and COMT, are associated with neural correlates of attentional encoding and attentional maintenance in WM, which in turn influence WM capacity. To explore this hypothesis, a combination of cutting-edge experimental techniques will be employed. Specifically, the applicant will use molecular genetics, electroencephalography/event-related potentials (EEG/ERPs), and behavioural measures to delve into the biological pathways underpinning the interplay between attentional control and WM capacity. The expected results will map to specific genotypes, the phenotypes (cognition/behaviour) and endophenotypes (neural markers/oscillations) of attentional encoding and attentional maintenance, and their modulation of WM. Findings will shed new light on the underlying mechanisms constraining WM capacity and shift the knowledge frontier. The proposal negotiates a subject matter of considerable importance for European society because WM deficits are a predominant symptom in many mental and neurological diseases that fall within Europe’s health priorities. During the proposed project, the fellow will acquire scientific and complementary transferable skills based on her personalized career development plan and through intra-European mobility and advanced training will reach a position of professional maturity in research.

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The information about "GENEVA" are provided by the European Opendata Portal: CORDIS opendata.

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