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TRANSMIT SIGNED

TRANSlating the role of Mitochondria in Tumorigenesis

Total Cost €

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EC-Contrib. €

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Partnership

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Outcomes and
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TRANSMIT project word cloud

Explore the words cloud of the TRANSMIT project. It provides you a very rough idea of what is the project "TRANSMIT" about.

enzymes shaping undergo cancers stage adverse disease training laboratories occurrence therapeutic evidences cancer types energy restructuring tumor critical date seven strategies contribution intermediates mitochondria bridging unravel transformed plasticity consolidation associations dna mass communication led skills profit omics translating scientific education multisectorial metabolism transmit survive portfolio centers patients biochemical young network transfer encoded multidisciplinary complementary actors mitochondrial oncogenes genetic microenvironment placing nuclear technologies care create devoted countries foundations cells scientists improvement industrial mutations dissect families biosynthetic clinical scenario remodeling metabolic world human translational basic full creation eleven excellence intricate place suppressors fosters science organelles

Project "TRANSMIT" data sheet

The following table provides information about the project.

Coordinator	ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA Organization address address: VIA ZAMBONI 33 city: BOLOGNA postcode: 40126 website: www.unibo.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Italy [IT]
Project website	http://www.transmit-project.eu
Total cost	2˙856˙812 €
EC max contribution	2˙856˙812 € (100%)
Programme	1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
Code Call	H2020-MSCA-ITN-2016
Funding Scheme	MSCA-ITN-ETN
Starting year	2017
Duration (year-month-day)	from 2017-01-01 to 2020-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA Organization address address: VIA ZAMBONI 33 city: BOLOGNA postcode: 40126 website: www.unibo.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (BOLOGNA)	coordinator	516˙122.00
2	AvantiCell Science Ltd AvantiCell Science Ltd Organization address address: GIBBSYARD BUILDING city: AYR postcode: KA6 5HW website: www.avanticell.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (AYR)	participant	273˙287.00
3	THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE Organization address address: TRINITY LANE THE OLD SCHOOLS city: CAMBRIDGE postcode: CB2 1TN website: www.cam.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (CAMBRIDGE)	participant	273˙287.00
4	KAROLINSKA INSTITUTET KAROLINSKA INSTITUTET Organization address address: Nobels Vag 5 city: STOCKHOLM postcode: 17177 website: www.ki.se contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SE (STOCKHOLM)	participant	263˙659.00
5	UNIVERSITE DE BORDEAUX UNIVERSITE DE BORDEAUX Organization address address: PLACE PEY BERLAND 35 city: BORDEAUX postcode: 33000 website: www.nouvelle-univ-bordeaux.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (BORDEAUX)	participant	262˙875.00
6	BIOCRATES LIFE SCIENCES AG BIOCRATES LIFE SCIENCES AG Organization address address: EDUARD BODEM GASSE 8 1 STOCK city: INNSBRUCK postcode: 6020 website: www.biocrates.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (INNSBRUCK)	participant	255˙934.00
7	GEMEINNUTZIGE SALZBURGER LANDESKLINIKEN BETRIEBSGESELLSCHAFT GEMEINNUTZIGE SALZBURGER LANDESKLINIKEN BETRIEBSGESELLSCHAFT Organization address address: MULLNER HAUPTSTRASSE 48 city: SALZBURG postcode: 5020 website: www.salk.at contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (SALZBURG)	participant	255˙934.00
8	OROBOROS INSTRUMENTS GmbH OROBOROS INSTRUMENTS GmbH Organization address address: SCHOPFSTRASSE 18 city: INNSBRUCK postcode: 6020 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (INNSBRUCK)	participant	255˙934.00
9	UNIVERSITE CATHOLIQUE DE LOUVAIN UNIVERSITE CATHOLIQUE DE LOUVAIN Organization address address: PLACE DE L UNIVERSITE 1 city: LOUVAIN LA NEUVE postcode: 1348 website: www.uclouvain.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (LOUVAIN LA NEUVE)	participant	250˙560.00
10	JUSTUS-LIEBIG-UNIVERSITAET GIESSEN JUSTUS-LIEBIG-UNIVERSITAET GIESSEN Organization address address: LUDWIGSTRASSE 23 city: GIESSEN postcode: 35390 website: www.uni-giessen.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (GIESSEN)	participant	249˙216.00
11	CEUB.SOC.CONS.ARL CEUB.SOC.CONS.ARL Organization address address: VIA FRANGIPANE 6 city: BERTINORO postcode: 47032 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (BERTINORO)	partner	0.00
12	Dynamo Academy srl Impresa Sociale Dynamo Academy srl Impresa Sociale Organization address address: via Ximenes 662 city: San Marcello Pistoiese postcode: 51028 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (San Marcello Pistoiese)	partner	0.00
13	FONDAZIONE UMBERTO VERONESI FONDAZIONE UMBERTO VERONESI Organization address address: PIAZZA VELASCA 5 city: MILANO postcode: 20122 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (MILANO)	partner	0.00
14	INNOVA SRL INNOVA SRL Organization address address: VIA CICERONE, 66 city: ROMA postcode: 193 website: www.innova-eu.net contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (ROMA)	partner	0.00

Map

Project objective

The consolidation of the knowledge that cancer is not only a genetic, but also a metabolic disease, has led scientists to investigate the intricate metabolic plasticity that transformed cells must undergo to survive the adverse tumor microenvironment conditions, and the contribution of oncogenes and tumor suppressors in shaping metabolism. In this scenario, genetic, biochemical and clinical evidences place mitochondria as key actors in cancer metabolic restructuring, not only because these organelles have a crucial role in the energy and biosynthetic intermediates production but also because occurrence of mutations in metabolic enzymes encoded by both nuclear and mitochondrial DNA has been associated to different types of cancer. TRANSMIT aims to dissect the metabolic remodeling in human cancers, placing the focus on the role of mitochondria and bridging basic research to the improvement/development of therapeutic strategies. Further, TRANSMIT fosters the communication of this emerging field to the patients and their families. To these aims, TRANSMIT will create a network of seven different countries, among which world-leading basic science and clinical centers of excellence, several industrial partners with up-to-date omics technologies, as well as non-profit foundations and associations who care for cancer patients. By creating the critical mass of scientific excellence, TRANSMIT will allow to transfer the current knowledge into the wide field of cancer research, translating scientific and technical advances into the education and training of eleven Early Stage Researchers. TRANSMIT will implement training-through-research dedicated to unravel the metabolic features of cancer, as well as to provide a full portfolio of complementary skills through the creation of a network of basic, translational and industrial laboratories, devoted to a multidisciplinary/multisectorial education of young scientists.

Deliverables

List of deliverables.
Summer School in Metabolomics	Documents, reports	2020-01-20 18:12:34
Representative of Trainees Elections	Documents, reports	2020-01-20 18:12:34
Recruitment procedure accomplished and list of ESRs appointed	Documents, reports	2020-01-20 18:12:34
Course in Cancer Metabolism	Documents, reports	2020-01-20 18:12:34
Progress report	Documents, reports	2020-01-20 18:12:34
Project Website	Documents, reports	2020-01-20 18:12:34
Project dissemination activities	Documents, reports	2020-01-20 18:12:34

Take a look to the deliverables list in detail: detailed list of TRANSMIT deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2018	Giulia Leone, Houda Abla, Giuseppe Gasparre, Anna Porcelli, Luisa Iommarini The Oncojanus Paradigm of Respiratory Complex I published pages: 243, ISSN: 2073-4425, DOI: 10.3390/genes9050243	Genes 9/5	2020-01-20
2018	Daniela D. Weber, Sepideh Aminazdeh-Gohari, Barbara Kofler Ketogenic diet in cancer therapy published pages: 164-165, ISSN: 1945-4589, DOI: 10.18632/aging.101382	Aging 10/2	2020-01-20

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