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TRANSMIT SIGNED

TRANSlating the role of Mitochondria in Tumorigenesis

Total Cost €

0

EC-Contrib. €

0

Partnership

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 TRANSMIT project word cloud

Explore the words cloud of the TRANSMIT project. It provides you a very rough idea of what is the project "TRANSMIT" about.

enzymes    shaping    undergo    cancers    stage    adverse    disease    training    laboratories    occurrence    therapeutic    evidences    cancer    types    energy    restructuring    tumor    critical    date    seven    strategies    contribution    intermediates    mitochondria    bridging    unravel    transformed    plasticity    consolidation    associations    dna    mass    communication    led    skills    profit    omics    translating    scientific    education    multisectorial    metabolism    transmit    survive    portfolio    centers    patients    biochemical    young    network    transfer    encoded    multidisciplinary    complementary    actors    mitochondrial    oncogenes    genetic    microenvironment    placing    nuclear    technologies    care    create    devoted    countries    foundations    cells    scientists    improvement    industrial    mutations    dissect    families    biosynthetic    clinical    scenario    remodeling    metabolic    world    human    translational    basic    full    creation    eleven    excellence    intricate    place    suppressors    fosters    science    organelles   

Project "TRANSMIT" data sheet

The following table provides information about the project.

Coordinator
ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA 

Organization address
address: VIA ZAMBONI 33
city: BOLOGNA
postcode: 40126
website: www.unibo.it

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Project website http://www.transmit-project.eu
 Total cost 2˙856˙812 €
 EC max contribution 2˙856˙812 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2016
 Funding Scheme MSCA-ITN-ETN
 Starting year 2017
 Duration (year-month-day) from 2017-01-01   to  2020-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA IT (BOLOGNA) coordinator 516˙122.00
2    AvantiCell Science Ltd UK (AYR) participant 273˙287.00
3    THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE UK (CAMBRIDGE) participant 273˙287.00
4    KAROLINSKA INSTITUTET SE (STOCKHOLM) participant 263˙659.00
5    UNIVERSITE DE BORDEAUX FR (BORDEAUX) participant 262˙875.00
6    BIOCRATES LIFE SCIENCES AG AT (INNSBRUCK) participant 255˙934.00
7    GEMEINNUTZIGE SALZBURGER LANDESKLINIKEN BETRIEBSGESELLSCHAFT AT (SALZBURG) participant 255˙934.00
8    OROBOROS INSTRUMENTS GmbH AT (INNSBRUCK) participant 255˙934.00
9    UNIVERSITE CATHOLIQUE DE LOUVAIN BE (LOUVAIN LA NEUVE) participant 250˙560.00
10    JUSTUS-LIEBIG-UNIVERSITAET GIESSEN DE (GIESSEN) participant 249˙216.00
11    CEUB.SOC.CONS.ARL IT (BERTINORO) partner 0.00
12    Dynamo Academy srl Impresa Sociale IT (San Marcello Pistoiese) partner 0.00
13    FONDAZIONE UMBERTO VERONESI IT (MILANO) partner 0.00
14    INNOVA SRL IT (ROMA) partner 0.00

Map

 Project objective

The consolidation of the knowledge that cancer is not only a genetic, but also a metabolic disease, has led scientists to investigate the intricate metabolic plasticity that transformed cells must undergo to survive the adverse tumor microenvironment conditions, and the contribution of oncogenes and tumor suppressors in shaping metabolism. In this scenario, genetic, biochemical and clinical evidences place mitochondria as key actors in cancer metabolic restructuring, not only because these organelles have a crucial role in the energy and biosynthetic intermediates production but also because occurrence of mutations in metabolic enzymes encoded by both nuclear and mitochondrial DNA has been associated to different types of cancer. TRANSMIT aims to dissect the metabolic remodeling in human cancers, placing the focus on the role of mitochondria and bridging basic research to the improvement/development of therapeutic strategies. Further, TRANSMIT fosters the communication of this emerging field to the patients and their families. To these aims, TRANSMIT will create a network of seven different countries, among which world-leading basic science and clinical centers of excellence, several industrial partners with up-to-date omics technologies, as well as non-profit foundations and associations who care for cancer patients. By creating the critical mass of scientific excellence, TRANSMIT will allow to transfer the current knowledge into the wide field of cancer research, translating scientific and technical advances into the education and training of eleven Early Stage Researchers. TRANSMIT will implement training-through-research dedicated to unravel the metabolic features of cancer, as well as to provide a full portfolio of complementary skills through the creation of a network of basic, translational and industrial laboratories, devoted to a multidisciplinary/multisectorial education of young scientists.

 Deliverables

List of deliverables.
Summer School in Metabolomics Documents, reports 2020-01-20 18:12:34
Representative of Trainees Elections Documents, reports 2020-01-20 18:12:34
Recruitment procedure accomplished and list of ESRs appointed Documents, reports 2020-01-20 18:12:34
Course in Cancer Metabolism Documents, reports 2020-01-20 18:12:34
Progress report Documents, reports 2020-01-20 18:12:34
Project Website Documents, reports 2020-01-20 18:12:34
Project dissemination activities Documents, reports 2020-01-20 18:12:34

Take a look to the deliverables list in detail:  detailed list of TRANSMIT deliverables.

 Publications

year authors and title journal last update
List of publications.
2018 Giulia Leone, Houda Abla, Giuseppe Gasparre, Anna Porcelli, Luisa Iommarini
The Oncojanus Paradigm of Respiratory Complex I
published pages: 243, ISSN: 2073-4425, DOI: 10.3390/genes9050243
Genes 9/5 2020-01-20
2018 Daniela D. Weber, Sepideh Aminazdeh-Gohari, Barbara Kofler
Ketogenic diet in cancer therapy
published pages: 164-165, ISSN: 1945-4589, DOI: 10.18632/aging.101382
Aging 10/2 2020-01-20

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