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TRANSMIT SIGNED

TRANSlating the role of Mitochondria in Tumorigenesis

Total Cost €

0

EC-Contrib. €

0

Partnership

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 TRANSMIT project word cloud

Explore the words cloud of the TRANSMIT project. It provides you a very rough idea of what is the project "TRANSMIT" about.

tumor    laboratories    biosynthetic    multidisciplinary    strategies    adverse    date    mass    basic    fosters    profit    creation    dna    centers    genetic    remodeling    transfer    metabolism    undergo    mitochondria    therapeutic    portfolio    critical    excellence    scientists    translating    plasticity    network    types    young    microenvironment    communication    science    survive    families    disease    led    education    translational    bridging    foundations    cancers    omics    clinical    full    training    stage    suppressors    restructuring    evidences    dissect    enzymes    metabolic    world    place    actors    contribution    occurrence    consolidation    placing    organelles    devoted    shaping    patients    create    intermediates    cancer    human    skills    cells    mutations    scientific    industrial    oncogenes    multisectorial    nuclear    seven    eleven    mitochondrial    care    encoded    intricate    transmit    scenario    technologies    energy    countries    associations    unravel    biochemical    transformed    improvement    complementary   

Project "TRANSMIT" data sheet

The following table provides information about the project.

Coordinator
ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA 

Organization address
address: VIA ZAMBONI 33
city: BOLOGNA
postcode: 40126
website: www.unibo.it

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Project website http://www.transmit-project.eu
 Total cost 2˙856˙812 €
 EC max contribution 2˙856˙812 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2016
 Funding Scheme MSCA-ITN-ETN
 Starting year 2017
 Duration (year-month-day) from 2017-01-01   to  2020-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA IT (BOLOGNA) coordinator 516˙122.00
2    AvantiCell Science Ltd UK (AYR) participant 273˙287.00
3    THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE UK (CAMBRIDGE) participant 273˙287.00
4    KAROLINSKA INSTITUTET SE (STOCKHOLM) participant 263˙659.00
5    UNIVERSITE DE BORDEAUX FR (BORDEAUX) participant 262˙875.00
6    BIOCRATES LIFE SCIENCES AG AT (INNSBRUCK) participant 255˙934.00
7    GEMEINNUTZIGE SALZBURGER LANDESKLINIKEN BETRIEBSGESELLSCHAFT AT (SALZBURG) participant 255˙934.00
8    OROBOROS INSTRUMENTS GmbH AT (INNSBRUCK) participant 255˙934.00
9    UNIVERSITE CATHOLIQUE DE LOUVAIN BE (LOUVAIN LA NEUVE) participant 250˙560.00
10    JUSTUS-LIEBIG-UNIVERSITAET GIESSEN DE (GIESSEN) participant 249˙216.00
11    CEUB.SOC.CONS.ARL IT (BERTINORO) partner 0.00
12    Dynamo Academy srl Impresa Sociale IT (San Marcello Pistoiese) partner 0.00
13    FONDAZIONE UMBERTO VERONESI IT (MILANO) partner 0.00
14    INNOVA SRL IT (ROMA) partner 0.00

Map

 Project objective

The consolidation of the knowledge that cancer is not only a genetic, but also a metabolic disease, has led scientists to investigate the intricate metabolic plasticity that transformed cells must undergo to survive the adverse tumor microenvironment conditions, and the contribution of oncogenes and tumor suppressors in shaping metabolism. In this scenario, genetic, biochemical and clinical evidences place mitochondria as key actors in cancer metabolic restructuring, not only because these organelles have a crucial role in the energy and biosynthetic intermediates production but also because occurrence of mutations in metabolic enzymes encoded by both nuclear and mitochondrial DNA has been associated to different types of cancer. TRANSMIT aims to dissect the metabolic remodeling in human cancers, placing the focus on the role of mitochondria and bridging basic research to the improvement/development of therapeutic strategies. Further, TRANSMIT fosters the communication of this emerging field to the patients and their families. To these aims, TRANSMIT will create a network of seven different countries, among which world-leading basic science and clinical centers of excellence, several industrial partners with up-to-date omics technologies, as well as non-profit foundations and associations who care for cancer patients. By creating the critical mass of scientific excellence, TRANSMIT will allow to transfer the current knowledge into the wide field of cancer research, translating scientific and technical advances into the education and training of eleven Early Stage Researchers. TRANSMIT will implement training-through-research dedicated to unravel the metabolic features of cancer, as well as to provide a full portfolio of complementary skills through the creation of a network of basic, translational and industrial laboratories, devoted to a multidisciplinary/multisectorial education of young scientists.

 Deliverables

List of deliverables.
Summer School in Metabolomics Documents, reports 2020-01-20 18:12:34
Representative of Trainees Elections Documents, reports 2020-01-20 18:12:34
Recruitment procedure accomplished and list of ESRs appointed Documents, reports 2020-01-20 18:12:34
Course in Cancer Metabolism Documents, reports 2020-01-20 18:12:34
Progress report Documents, reports 2020-01-20 18:12:34
Project Website Documents, reports 2020-01-20 18:12:34
Project dissemination activities Documents, reports 2020-01-20 18:12:34

Take a look to the deliverables list in detail:  detailed list of TRANSMIT deliverables.

 Publications

year authors and title journal last update
List of publications.
2018 Giulia Leone, Houda Abla, Giuseppe Gasparre, Anna Porcelli, Luisa Iommarini
The Oncojanus Paradigm of Respiratory Complex I
published pages: 243, ISSN: 2073-4425, DOI: 10.3390/genes9050243
Genes 9/5 2020-01-20
2018 Daniela D. Weber, Sepideh Aminazdeh-Gohari, Barbara Kofler
Ketogenic diet in cancer therapy
published pages: 164-165, ISSN: 1945-4589, DOI: 10.18632/aging.101382
Aging 10/2 2020-01-20

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