Opendata, web and dolomites

CarBon SIGNED

Controlling Cartilage to Bone Transitions for Improved Treatment of Bone Defects and Osteoarthritis

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 CarBon project word cloud

Explore the words cloud of the CarBon project. It provides you a very rough idea of what is the project "CarBon" about.

options    suffer    transitions    diseases    computational    skilled    developmental    transition    prevent    stage    multifactorial    academic    equipped    life    scientists    understand    train    companies    combine    cutting    physical    models    intellectual    combined    insufficient    foundations    societal    fate    network    aging    tissue    treatment    transferable    young    drugs    bioreactors    orchestrated    vitro    charitable    therapeutic    disciplines    discover    carbon    functioning    functionalised    healing    bone    leads    either    modulated    treatments    edge    property    biotechnology    dual    cell    defects    scientific    pathobiology    consideration    biomaterials    drug    trained    quality    vivo    uniquely    stimulate    esrs    biological    pivotal    population    engineering    elucidate    human    locomotor    careers    discovery    impairs    silico    skills    14    biology    foundation    communication    cartilage    osteoarthritis    people    expertise    undesired    character   

Project "CarBon" data sheet

The following table provides information about the project.

Coordinator
ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM 

Organization address
address: DR MOLEWATERPLEIN 40
city: ROTTERDAM
postcode: 3015 GD
website: www.erasmusmc.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Project website http://www.carbonresearch.eu
 Total cost 3˙607˙596 €
 EC max contribution 3˙607˙596 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2016
 Funding Scheme MSCA-ITN-ETN
 Starting year 2017
 Duration (year-month-day) from 2017-01-01   to  2020-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM NL (ROTTERDAM) coordinator 766˙122.00
2    KATHOLIEKE UNIVERSITEIT LEUVEN BE (LEUVEN) participant 751˙680.00
3    THE ROYAL VETERINARY COLLEGE UK (LONDON) participant 546˙575.00
4    SURGACOLL TECHNOLOGIES LIMITED IE (DUBLIN) participant 265˙674.00
5    THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN IE (DUBLIN) participant 265˙674.00
6    IRCCS OSPEDALE POLICLINICO SAN MARTINO IT (GENOVA) participant 258˙061.00
7    LIFETEC GROUP BV NL (EINDHOVEN) participant 255˙374.00
8    JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN DE (FRANKFURT AM MAIN) participant 249˙216.00
9    KLINIKUM DER UNIVERSITAET ZU KOELN DE (KOELN) participant 249˙216.00
10    Deutsche Arthrosehilfe DE (Frankfurt am Main) partner 0.00
11    Eli Lilly and Company UM (Indianapolis) partner 0.00
12    Orthopaedic Research UK UK (London) partner 0.00
13    STICHTING NATIONAAL REUMAFONDS NL (AMSTERDAM) partner 0.00

Map

 Project objective

A well-functioning locomotor system is essential for human well-being. This is an important consideration in our aging population with the increased associated costs of ensuring high quality of life. Many people suffer from diseases of the locomotor system, such as bone defects or osteoarthritis, for which current treatments are insufficient. To develop new treatments, CarBon includes 6 academic partners, 3 companies and 3 charitable foundations, working together to train 14 young scientists. We will combine knowledge from the fields of tissue engineering, cartilage and bone developmental biology and pathobiology using skills from the disciplines of cell biology, computational modelling, biotechnology (bioreactors, biomaterials) and drug discovery.

In a multifactorial approach the network of young scientists will identify the biological and physical factors that determine the fate of cartilage. Understanding and controlling the dual character of cartilage is pivotal: insufficient transition impairs bone healing, and undesired transition to bone leads to osteoarthritis. State of the art in vitro, in silico and in vivo models will be uniquely combined to elucidate how this transition is orchestrated and how it can be modulated.

The main objectives of CarBon are: - To establish a network of 14 highly skilled early stage researchers (ESRs) equipped with essential knowledge, scientific expertise, transferable skills and societal awareness as a foundation for their future careers. ESRs will be trained in cutting edge technology, communication, intellectual property and valorisation. - To understand cartilage to bone transition, to identify targets to develop novel functionalised biomaterials and to discover therapeutic drugs that either prevent or stimulate cartilage to bone transitions. This will lead to new treatment options for large bone defects and osteoarthritis.

 Deliverables

List of deliverables.
D6.1 Documents, reports 2019-07-05 15:23:53
D7.1 Websites, patent fillings, videos etc. 2019-07-05 15:23:53
D7.2 Websites, patent fillings, videos etc. 2019-07-05 15:23:53

Take a look to the deliverables list in detail:  detailed list of CarBon deliverables.

 Publications

year authors and title journal last update
List of publications.
2019 Andrew Pitsillides, Soraia P Caetano-Silva
Faculty of 1000 evaluation for Genome-wide association and functional studies identify a role for matrix Gla protein in osteoarthritis of the hand.
published pages: , ISSN: , DOI: 10.3410/f.730362852.793539430
2020-04-07
2019 Cansu Gorgun, Daniele Reverberi, Gianluca Rotta, Federico Villa, Rodolfo Quarto, Roberta Tasso
Isolation and Flow Cytometry Characterization of Extracellular-Vesicle Subpopulations Derived from Human Mesenchymal Stromal Cells
published pages: e76, ISSN: 1941-7322, DOI: 10.1002/cpsc.76
Current Protocols in Stem Cell Biology 48/1 2019-08-29
2018 Behzad Javaheri, Soraia P. Caetano-Silva, Ioannis Kanakis, George Bou-Gharios, Andrew A. Pitsillides
The Chondro-Osseous Continuum: Is It Possible to Unlock the Potential Assigned Within?
published pages: , ISSN: 2296-4185, DOI: 10.3389/fbioe.2018.00028
Frontiers in Bioengineering and Biotechnology 6 2019-07-05
2018 Raphaelle Lesage, Johan Kerkhofs, Liesbet Geris
Computational Modeling and Reverse Engineering to Reveal Dominant Regulatory Interactions Controlling Osteochondral Differentiation: Potential for Regenerative Medicine
published pages: , ISSN: 2296-4185, DOI: 10.3389/fbioe.2018.00165
Frontiers in Bioengineering and Biotechnology 6 2019-07-05

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "CARBON" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "CARBON" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.1.)

BIGMATH (2018)

Big Data Challenges for Mathematics

Read More  

NanoCarb (2018)

Glyco-Nanoparticles for Applications in Advance Nanomedicine

Read More  

LongActNow (2019)

Long Acting Medicines for Complex Therapeutics Needed Now

Read More