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GROWTH SIGNED

Research and Training in Early Life Nutrition to Prevent Disease

Total Cost €

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EC-Contrib. €

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Partnership

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Project "GROWTH" data sheet

The following table provides information about the project.

Coordinator
DSCN RESEARCH B.V. 

Organization address
address: KLOKKENBERGWEG 8
city: AMSTERDAM
postcode: 1101 AS
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 2˙183˙583 €
 EC max contribution 2˙183˙583 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2018
 Funding Scheme MSCA-ITN-EID
 Starting year 2019
 Duration (year-month-day) from 2019-06-01   to  2023-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    DSCN RESEARCH B.V. NL (AMSTERDAM) coordinator 265˙619.00
2    UNIVERSITATSKLINIKUM BONN DE (BONN) participant 505˙576.00
3    IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE UK (LONDON) participant 303˙172.00
4    RECKITT BENCKISER PLC UK (SLOUGH) participant 303˙172.00
5    CHERRY BIOTECH FR (RENNES) participant 274˙802.00
6    ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM NL (AMSTERDAM) participant 265˙619.00
7    STICHTING VUMC NL (AMSTERDAM) participant 265˙619.00

Map

 Project objective

The interplay between nutrition, gut microbiota, and its large numberof metabolic and immune mediators plays an essential role in the development of gut immune homeostasis in early life. This interaction needs to be better understood because a disturbed immune function in the neonatal period is harmful for neonatal survival and enhances the risk of chronic inflammatory disease later in life. In particular, preterm infants have an immature gut and an associated intestinal state of dysbiosis, which limits the efficacy of nutritional interventions to 1) support early life nutrition, 2) prevent sepsis and conditions such as necrotizing enterocolitis and intestinal failure, and 3) reduce the risk of chronic inflammatory diseases mediated by the gut. A major barrier to elucidating the critical nutritional-host-microbiome interactions and reducing neonatal mortality is the lack of expertise in this rapidly emerging area of metabolomics. We therefore proposes a multidisciplinary approach making use of a large-scale pre-existing clinical cohort of neonates, and state of the art analytical and bio-informatics tools. GROWTH is an Innovative Training Network focused on European Industrial Doctorates that aims to train young business-oriented researchers in developing pathological insights, biomarker diagnostics and personalized nutritional interventions for intestinal failure in neonates and preterm infants. As a multidisciplinary consortium that will involve the participation of 7 non-academic and 5 academic partners in the life sciences field and will attempt shortening the path from basic research to clinical applications.

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The information about "GROWTH" are provided by the European Opendata Portal: CORDIS opendata.

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