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PHA-ST-TRAIN-VAC SIGNED

Leveraging Pharmaceutical Sciences and Structural Biology Training to develop 21st Century Vaccines

Total Cost €

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EC-Contrib. €

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Partnership

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 PHA-ST-TRAIN-VAC project word cloud

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Project "PHA-ST-TRAIN-VAC" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITY OF STRATHCLYDE 

Organization address
address: Richmond Street 16
city: GLASGOW
postcode: G1 1XQ
website: www.strath.ac.uk

contact info
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 Coordinator Country United Kingdom [UK]
 Project website http://www.phast-train-vac.eu/
 Total cost 1˙062˙698 €
 EC max contribution 1˙062˙698 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2015
 Funding Scheme MSCA-ITN-EID
 Starting year 2016
 Duration (year-month-day) from 2016-06-01   to  2020-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITY OF STRATHCLYDE UK (GLASGOW) coordinator 546˙575.00
2    GLAXOSMITHKLINE VACCINES SRL IT (SIENA) participant 516˙122.00

Map

 Project objective

Immunisation is one of the most cost-effective and proven tools to control and eliminate infectious diseases, saving millions of lives each year, yet key challenges remain in order to guarantee the future health of the expanding and ageing global population. For example, effective vaccines are still required for Respiratory Syncytial Virus (RSV) and Group B Streptococcus (GBS), both of which cause significant hospitalisations globally each year. RSV is a common cause of respiratory disease among all age groups; annually it results in an estimated 33.8 million acute lower respiratory tract infections (resulting in 66,000-199,000 deaths) and among the elderly, it results in as many hospitalisations as influenza. Group B Streptococcus (GBS) infections also pose a serious risk; GBS is a leading cause of invasive infections in pregnant women, new-born infants, and the elderly. To meet the challenge of developing fit-for-purpose, age-appropriate vaccines against these disease targets, this EID will bring together two cross-sector, world leading teams – GSK Vaccines S.r.L and the University of Strathclyde – with the objective to equip the next generation of vaccinologists with the skills and tools to deliver vaccines for the 21st Century. GSK Vaccines S.r.L is a global leader in vaccine research, development and production and will work in partnership with the vaccine team within USTRATH and the Strathclyde Institute of Pharmacy and Biomedical Sciences, who have an international track-record of translatable and innovative research in immunology, immunomodulation, structural biology, and formulation design and pharmaceutical engineering of vaccine systems. PHA-ST-TRAIN-VAC will deliver a unique, multidisciplinary and intersectoral training programme to develop and equip four early stage researchers with the required skills and entrepreneurship to develop new vaccines to protect against RSV and GBS, in a formulation tailored to the age of the patient.

 Deliverables

List of deliverables.
Identification of RSV antigen for alternative vaccination routes Documents, reports 2020-04-08 10:20:48
Bio-distribution of adjuvants and their associated antigen - 1 Documents, reports 2020-04-08 10:20:48
Data management plan Open Research Data Pilot 2020-04-08 10:20:48
Interactions of GBS and RSV antigen and adjuvants Documents, reports 2020-04-08 10:20:48
Key biophysical and physico-chemical attributes of current lipid nanoparticles Documents, reports 2020-04-08 10:20:48
Metabolic factors that contribute to the impaired adaptive immunity in older adults Documents, reports 2020-04-08 10:20:48
Bio-distribution of lipid nanoparticles Documents, reports 2020-04-08 10:20:47
Key physico-chemical attributes of alum, emulsion, liposome and nanoparticle systems shown to be effective as adjuvants Documents, reports 2020-04-08 10:20:47
Model to investigate intracellular ROS, antigen presentation and specific T cell responses Documents, reports 2020-04-08 10:20:48
Identification of self-amplifying RSV RNA construct Documents, reports 2020-04-08 10:20:48
Comparison of cellular uptake in monocyte-derived macrophages and dendritic cells Documents, reports 2020-04-08 10:20:48

Take a look to the deliverables list in detail:  detailed list of PHA-ST-TRAIN-VAC deliverables.

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The information about "PHA-ST-TRAIN-VAC" are provided by the European Opendata Portal: CORDIS opendata.

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