#	Pagina
attuale pagina	/open-h2020/projects/205718/index.html
-1	/open-h2020/projects/225225/index.html

Opendata, web and dolomites

DanioPattern SIGNED

Development and Evolution of Colour Patterns in Danio species

Total Cost €

EC-Contrib. €

Partnership

Views

Outcomes and
results

DanioPattern project word cloud

Explore the words cloud of the DanioPattern project. It provides you a very rough idea of what is the project "DanioPattern" about.

alternating chromatophore basis body natural diversity interactions genus building patterning blue functions explore kin exchanging fins divergent genome allelic displays chromatophores evolve lay genetic stripes zebrafish channels danio junctions significance fundamental thorough environment species revealed tested altered evolution tracing cellular camouflage molecular mate colour mutants spectacularly mode mediated mechanisms single communication conspicuous rerio first recognition golden transcriptomes insights evolutionary direct foundation analysed animals anal organism biodiversity genes model influence tailfins sexual pigment lineage cas9 play candidate prominent pattern diversities vertebrate patterns biology crispr stripe opportunity sequences variation vertebrates disease variants understand closely

Project "DanioPattern" data sheet

The following table provides information about the project.

Coordinator	MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV Organization address address: HOFGARTENSTRASSE 8 city: Munich postcode: 80539 website: www.mpg.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Germany [DE]
Total cost	2˙250˙000 €
EC max contribution	2˙250˙000 € (100%)
Programme	1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
Code Call	ERC-2015-AdG
Funding Scheme	ERC-ADG
Starting year	2016
Duration (year-month-day)	from 2016-11-01 to 2021-04-30

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV Organization address address: HOFGARTENSTRASSE 8 city: Munich postcode: 80539 website: www.mpg.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (Munich)	coordinator	2˙250˙000.00

Map

Project objective

Colour patterns are prominent features of many animals and have important functions in communication such as camouflage, kin recognition and mate selection. Colour patterns are highly variable and evolve rapidly leading to large diversities even within a single genus. As targets for natural as well as sexual selection, they are of high evolutionary significance. The zebrafish (Danio rerio), a vertebrate model organism for the study of development and disease, displays a conspicuous pattern of alternating blue and golden stripes on the body and on the anal- and tailfins. Mutants with spectacularly altered patterns have been analysed, and novel approaches in lineage tracing have provided first insights into the cellular and molecular basis of colour patterning. These studies revealed that the mechanisms at play are novel and of fundamental interest to the biology of pattern formation. Closely related Danio species have very divergent colour patterns in body and fins offering the unique opportunity to study development and evolution of colour patterns in vertebrates building on the thorough analysis of one model species. Our research in zebrafish will explore the basis of direct interactions between chromatophores mediated by channels and junctions. We will investigate the divergent mode of stripe formation in the fins and the molecular influence of the cellular environment on chromatophore interactions. In closely related Danio species, we will investigate the cellular interactions during pattern formation. We will analyse transcriptomes and genome sequences to identify candidate genes providing the molecular basis for pigment pattern diversity. These candidate genes will be tested by creating mutants and exchanging allelic variants using the CRISPR/Cas9 system. The work will lay the foundation to understand not only the genetic basis of variation in colour pattern formation between Danio species, but also the evolution of biodiversity in other vertebrates.

Publications

List of publications.
year	authors and title	journal	last update
2020	Anastasia Eskova, Hans Georg FrohnhÃ¶fer, Christiane NÃ¼sslein-Volhard, Uwe Irion Galanin Signaling in the Brain Regulates Color Pattern Formation in Zebrafish published pages: 298-303.e3, ISSN: 0960-9822, DOI: 10.1016/j.cub.2019.11.033	Current Biology 30/2	2020-02-19
2019	Uwe Irion, Christiane NÃ¼sslein-Volhard The identification of genes involved in the evolution of color patterns in fish published pages: 31-38, ISSN: 0959-437X, DOI: 10.1016/j.gde.2019.07.002	Current Opinion in Genetics & Development 57	2020-01-28
2018	Andrey Fadeev, Patricia Mendoza-Garcia, Uwe Irion, Jikui Guan, Kathrin Pfeifer, Stephanie Wiessner, Fabrizio Serluca, Ajeet Pratap Singh, Christiane NÃ¼sslein-Volhard, Ruth H. Palmer ALKALs are in vivo ligands for ALK family receptor tyrosine kinases in the neural crest and derived cells published pages: E630-E638, ISSN: 0027-8424, DOI: 10.1073/pnas.1719137115	Proceedings of the National Academy of Sciences 115/4	2019-04-13

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "DANIOPATTERN" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "DANIOPATTERN" are provided by the European Opendata Portal: CORDIS opendata.