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MAGNAMED SIGNED

Novel magnetic nanostructures for medical applications

Total Cost €

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EC-Contrib. €

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Partnership

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Project "MAGNAMED" data sheet

The following table provides information about the project.

Coordinator
UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA 

Organization address
address: BARRIO SARRIENA S N
city: LEIOA
postcode: 48940
website: www.ehu.es

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Total cost 846˙000 €
 EC max contribution 846˙000 € (100%)
 Programme 1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
 Code Call H2020-MSCA-RISE-2016
 Funding Scheme /MSCA-RISE
 Starting year 2017
 Duration (year-month-day) from 2017-04-01   to  2021-03-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA ES (LEIOA) coordinator 310˙500.00
2    UNIVERSIDADE DO PORTO PT (PORTO) participant 148˙500.00
3    VIENNA BIOCENTER CORE FACILITES GMBH AT (WIEN) participant 117˙000.00
4    INESC MICROSISTEMAS E NANOTECNOLGIAS-INSTITUTO DE ENGENHARIA DE SISTEMAS DE COMPUTADORES PARA OS MICROSISTEMAS E AS NANOTECNOLOGIAS PT (LISBOA) participant 99˙000.00
5    ICETA INSTITUTO DE CIENCIAS, TECNOLOGIAS E AGROAMBIENTE DA UNIVERSIDADE DO PORTO PT (PORTO) participant 67˙500.00
6    IMG PHARMA BIOTECH SOCIEDAD LIMITADA ES (DERIO) participant 54˙000.00
7    UNIVERSIDAD COMPLUTENSE DE MADRID ES (MADRID) participant 27˙000.00
8    NANOVEX BIOTECHNOLOGIES SL ES (LLANERA) participant 22˙500.00
9    COMISION NACIONAL DE ENERGIA ATOMICA AR (BUENOS AIRES) partner 0.00
10    COMISSAO NACIONAL DE ENERGIA NUCLEAR- CENTRO DE DESENVOLVIMENTO DA TECNOLOGIA NUCLEAR BR (RIO DE JANEIRO) partner 0.00
11    THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US (OAKLAND CA) partner 0.00
12    THE UNIVERSITY OF TEXAS SYSTEM US (AUSTIN) partner 0.00
13    UNIVERSIDAD DE SANTIAGO DE CHILE CL (SANTIAGO) partner 0.00
14    UNIVERSIDAD TECNICA FEDERICO SANTA MARIA CL (VALPARAISO) partner 0.00
15    UNIVERSIDADE ESTADUAL DE CAMPINAS BR (CAMPINAS SP) partner 0.00

Mappa

 Project objective

MAGNAMED designs, fabricates, and assesses novel magnetic nanostructures (MNS) with unique spin configurations for innovative diagnostics and therapy techniques. An early stage detection and an effective treatment are keystones to reduce cancer mortality. Current clinical procedures fail to detect small concentration of tumoral biomarkers. Magnetic nanoparticles (MNP), like beads, have attracted much attention for their capability to improve cancer detection limits and treatment technologies. However, there are several limitations to the use of MNP. As an emerging alternative, MNS are being explored. Unlike MNP, MNS (e.g. nanodisks) present a planar shape with novel properties for diagnosis: high magnetic moment and large size, which can significantly improve the sensor sensitivity, and for therapy: due to their planar shape, alternate magnetic fields provoke a magneto-mechanical action on the cell membrane that triggers cell death. The efficiency of MNS in these two medical applications has not been investigated yet for MNS at the nanometer scale. The challenge of this project is to produce MNS with nanometer dimensions suitable for medical applications. Several lithography techniques will be used to fabricate MNS in vortex and antiferromagnetic spin configurations covering a broad size range (40 to 4000 nm). After functionalization, MNS will be exploited in: (i) Diagnostics, using giant magnetoresistance (GMR) sensors for the detection of tumoral biomarkers (dermcidin and carcinoembryonic antigen), and (ii) Therapy, effectiveness of tumoral cell annihilation by the magneto-mechanical action of MNS will be evaluated in vitro assays of melanoma and colorectal cancer cells. MAGNAMED is a cross-sectoral and interdisciplinary project involving Physics, Chemistry and Medicine. Findings will have a medium-term impact on the European strategy for early stage detection of cancer and a long-term impact on the development of novel and groundbreaking therapeutics techniques.

 Work performed, outcomes and results:  advancements report(s) 

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The information about "MAGNAMED" are provided by the European Opendata Portal: CORDIS opendata.

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