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NEOFIBRIN

Advanced material for the regeneration of oral mucosa injuries

Total Cost €

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EC-Contrib. €

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Partnership

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 NEOFIBRIN project word cloud

Explore the words cloud of the NEOFIBRIN project. It provides you a very rough idea of what is the project "NEOFIBRIN" about.

marketed    grafts    supportive    larger    instrument    extracellular    rights    plan    medicine    mucosa    suturing    invasion    mark    oral    efficiency    techniques    consistency    maturation    structural    tissues    mechanical    wound    histocell    capacity    completion    engineering    successful    restoring    autologous    functional    proliferation    industrialization    scaffolds    damage    mucosal    seaweed    manufacturing    proteins    phases    facility    neofibrin    artificial    fibrin    obtain    human    accomplishment    market    specialized    generation    localized    scaffold    matrix    cell    regeneration    sme    hr018    provides    feasibility    company    sem    maintaining    treatment    tissue    epithelium    biomaterial    migration    masticatory    combining    facilitates    allogenic    alternative    significantly    temporary    progressive    treat    gives    surgical    clinical    accelerating    material    yield    dentistry    seek    materials    injuries    exclusive    polysaccharide    licensing    ce    tridimensional    innovative    healing    medical    adapt    agarose    business    regenerative    natural   

Project "NEOFIBRIN" data sheet

The following table provides information about the project.

Coordinator
HISTOCELL SL 

Organization address
address: PARQUE TECNOLOGICO DE BIZKAIA EDIFICIO 801 PISO 2
city: DERIO BIZKAIA
postcode: 48160
website: www.histocell.com

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Project website http://www.histocell.com/index.php/en/r-d/current-projects/138-neofibrin
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.2.1.5. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Advanced manufacturing and processing)
2. H2020-EU.2.1.3. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Advanced materials)
3. H2020-EU.2.3.1. (Mainstreaming SME support, especially through a dedicated instrument)
4. H2020-EU.2.1.2. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Nanotechnologies)
 Code Call H2020-SMEINST-1-2016-2017
 Funding Scheme SME-1
 Starting year 2017
 Duration (year-month-day) from 2017-02-01   to  2017-07-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    HISTOCELL SL ES (DERIO BIZKAIA) coordinator 50˙000.00

Map

Leaflet | Map data © OpenStreetMap contributors, CC-BY-SA, Imagery © Mapbox

 Project objective

The main objective of NEOFIBRIN is to undertake a technical, industrialization and market feasibility study on an innovative regenerative medicine treatment for masticatory oral mucosa injuries based on a new advanced material, HR018-Neofibrin. The use of this material to develop a tridimensional natural scaffold for restoring masticatory oral mucosa functional activity is expected to significantly increase treatment efficiency over currently marketed products and to provide an alternative to allogenic and autologous grafts to treat localized mucosal damage. The application of Tissue Engineering techniques in clinical dentistry has several well-known problems, key among them the generation of a supportive biomaterial with regenerative capacity without the loss of consistency. Our novel biomaterial HR018-Neofibrin was developed combining natural materials and an exclusive design to promote the progressive formation and maturation of new epithelium while maintaining structural properties. Fibrin, one of the proteins involved in wound healing, provides a temporary extracellular matrix that facilitates cell migration, invasion and proliferation. Agarose, a polysaccharide from seaweed, gives the mechanical properties that enable surgical suturing and open healing. Histocell, a SME specialized in human regenerative medicine, has obtained licensing rights to the production of fibrin-agarose based artificial tissues and scaffolds for regeneration of tissues and oral mucosa. Successful completion of Phase 1 of NEOFIBRIN will yield a robust business plan for a much larger project that will seek funding under Phase 2 of the SEM Instrument, when the company will adapt a new facility for advanced manufacturing of innovative medical devices for the production of the new biomaterial HR018-Neofibrin and undertake clinical studies to obtain CE Mark for the product. Successful accomplishment of Phases 1 and 2 will be essential for accelerating the growth of the SME Histocell.

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The information about "NEOFIBRIN" are provided by the European Opendata Portal: CORDIS opendata.

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