Opendata, web and dolomites


Advanced material for the regeneration of oral mucosa injuries

Total Cost €


EC-Contrib. €






 NEOFIBRIN project word cloud

Explore the words cloud of the NEOFIBRIN project. It provides you a very rough idea of what is the project "NEOFIBRIN" about.

allogenic    sme    functional    techniques    natural    licensing    polysaccharide    seaweed    feasibility    sem    healing    efficiency    human    suturing    mechanical    damage    invasion    progressive    maintaining    treatment    accelerating    instrument    supportive    epithelium    structural    plan    tridimensional    mucosa    medical    adapt    medicine    artificial    generation    completion    dentistry    clinical    agarose    consistency    company    oral    engineering    treat    larger    facilitates    histocell    regenerative    matrix    mark    ce    biomaterial    fibrin    proteins    proliferation    exclusive    masticatory    innovative    extracellular    surgical    tissue    business    alternative    autologous    material    specialized    industrialization    manufacturing    tissues    hr018    market    successful    neofibrin    materials    cell    maturation    scaffold    significantly    capacity    accomplishment    marketed    temporary    localized    regeneration    migration    wound    provides    grafts    seek    phases    scaffolds    rights    combining    restoring    mucosal    injuries    facility    obtain    gives    yield   

Project "NEOFIBRIN" data sheet

The following table provides information about the project.


Organization address
postcode: 48160

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Project website
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.2.1.5. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Advanced manufacturing and processing)
2. H2020-EU.2.1.3. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Advanced materials)
3. H2020-EU.2.3.1. (Mainstreaming SME support, especially through a dedicated instrument)
4. H2020-EU.2.1.2. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Nanotechnologies)
 Code Call H2020-SMEINST-1-2016-2017
 Funding Scheme SME-1
 Starting year 2017
 Duration (year-month-day) from 2017-02-01   to  2017-07-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    HISTOCELL SL ES (DERIO BIZKAIA) coordinator 50˙000.00


 Project objective

The main objective of NEOFIBRIN is to undertake a technical, industrialization and market feasibility study on an innovative regenerative medicine treatment for masticatory oral mucosa injuries based on a new advanced material, HR018-Neofibrin. The use of this material to develop a tridimensional natural scaffold for restoring masticatory oral mucosa functional activity is expected to significantly increase treatment efficiency over currently marketed products and to provide an alternative to allogenic and autologous grafts to treat localized mucosal damage. The application of Tissue Engineering techniques in clinical dentistry has several well-known problems, key among them the generation of a supportive biomaterial with regenerative capacity without the loss of consistency. Our novel biomaterial HR018-Neofibrin was developed combining natural materials and an exclusive design to promote the progressive formation and maturation of new epithelium while maintaining structural properties. Fibrin, one of the proteins involved in wound healing, provides a temporary extracellular matrix that facilitates cell migration, invasion and proliferation. Agarose, a polysaccharide from seaweed, gives the mechanical properties that enable surgical suturing and open healing. Histocell, a SME specialized in human regenerative medicine, has obtained licensing rights to the production of fibrin-agarose based artificial tissues and scaffolds for regeneration of tissues and oral mucosa. Successful completion of Phase 1 of NEOFIBRIN will yield a robust business plan for a much larger project that will seek funding under Phase 2 of the SEM Instrument, when the company will adapt a new facility for advanced manufacturing of innovative medical devices for the production of the new biomaterial HR018-Neofibrin and undertake clinical studies to obtain CE Mark for the product. Successful accomplishment of Phases 1 and 2 will be essential for accelerating the growth of the SME Histocell.

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The information about "NEOFIBRIN" are provided by the European Opendata Portal: CORDIS opendata.

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