Opendata, web and dolomites


Advanced material for the regeneration of oral mucosa injuries

Total Cost €


EC-Contrib. €






 NEOFIBRIN project word cloud

Explore the words cloud of the NEOFIBRIN project. It provides you a very rough idea of what is the project "NEOFIBRIN" about.

efficiency    specialized    seaweed    tissues    histocell    marketed    yield    feasibility    surgical    fibrin    clinical    natural    epithelium    migration    facilitates    allogenic    neofibrin    supportive    combining    restoring    tridimensional    maintaining    injuries    mechanical    tissue    oral    damage    gives    temporary    mucosa    generation    mark    regenerative    medical    consistency    completion    successful    sme    regeneration    capacity    seek    manufacturing    market    plan    suturing    localized    licensing    company    material    artificial    masticatory    facility    treatment    larger    proliferation    obtain    exclusive    accelerating    rights    phases    engineering    industrialization    accomplishment    techniques    materials    scaffold    wound    functional    progressive    treat    grafts    maturation    business    significantly    human    adapt    agarose    structural    biomaterial    autologous    innovative    medicine    scaffolds    hr018    cell    alternative    mucosal    matrix    extracellular    polysaccharide    provides    invasion    ce    dentistry    proteins    sem    instrument    healing   

Project "NEOFIBRIN" data sheet

The following table provides information about the project.


Organization address
postcode: 48160

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Project website
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.2.1.5. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Advanced manufacturing and processing)
2. H2020-EU.2.1.3. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Advanced materials)
3. H2020-EU.2.3.1. (Mainstreaming SME support, especially through a dedicated instrument)
4. H2020-EU.2.1.2. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Nanotechnologies)
 Code Call H2020-SMEINST-1-2016-2017
 Funding Scheme SME-1
 Starting year 2017
 Duration (year-month-day) from 2017-02-01   to  2017-07-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    HISTOCELL SL ES (DERIO BIZKAIA) coordinator 50˙000.00


 Project objective

The main objective of NEOFIBRIN is to undertake a technical, industrialization and market feasibility study on an innovative regenerative medicine treatment for masticatory oral mucosa injuries based on a new advanced material, HR018-Neofibrin. The use of this material to develop a tridimensional natural scaffold for restoring masticatory oral mucosa functional activity is expected to significantly increase treatment efficiency over currently marketed products and to provide an alternative to allogenic and autologous grafts to treat localized mucosal damage. The application of Tissue Engineering techniques in clinical dentistry has several well-known problems, key among them the generation of a supportive biomaterial with regenerative capacity without the loss of consistency. Our novel biomaterial HR018-Neofibrin was developed combining natural materials and an exclusive design to promote the progressive formation and maturation of new epithelium while maintaining structural properties. Fibrin, one of the proteins involved in wound healing, provides a temporary extracellular matrix that facilitates cell migration, invasion and proliferation. Agarose, a polysaccharide from seaweed, gives the mechanical properties that enable surgical suturing and open healing. Histocell, a SME specialized in human regenerative medicine, has obtained licensing rights to the production of fibrin-agarose based artificial tissues and scaffolds for regeneration of tissues and oral mucosa. Successful completion of Phase 1 of NEOFIBRIN will yield a robust business plan for a much larger project that will seek funding under Phase 2 of the SEM Instrument, when the company will adapt a new facility for advanced manufacturing of innovative medical devices for the production of the new biomaterial HR018-Neofibrin and undertake clinical studies to obtain CE Mark for the product. Successful accomplishment of Phases 1 and 2 will be essential for accelerating the growth of the SME Histocell.

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The information about "NEOFIBRIN" are provided by the European Opendata Portal: CORDIS opendata.

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