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NEOFIBRIN

Advanced material for the regeneration of oral mucosa injuries

Total Cost €

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EC-Contrib. €

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Partnership

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 NEOFIBRIN project word cloud

Explore the words cloud of the NEOFIBRIN project. It provides you a very rough idea of what is the project "NEOFIBRIN" about.

restoring    proliferation    fibrin    functional    mucosa    exclusive    business    scaffolds    agarose    seek    polysaccharide    mechanical    facilitates    natural    specialized    artificial    autologous    yield    gives    regeneration    damage    ce    mucosal    obtain    regenerative    surgical    medicine    structural    hr018    tissues    allogenic    maturation    market    engineering    cell    seaweed    sem    dentistry    completion    proteins    oral    sme    company    medical    human    rights    invasion    masticatory    supportive    accomplishment    histocell    healing    licensing    industrialization    adapt    clinical    larger    materials    scaffold    plan    facility    efficiency    suturing    matrix    instrument    injuries    techniques    successful    innovative    tridimensional    combining    provides    generation    material    maintaining    mark    neofibrin    consistency    accelerating    capacity    marketed    epithelium    biomaterial    extracellular    alternative    tissue    temporary    significantly    localized    migration    progressive    feasibility    treatment    grafts    phases    wound    treat    manufacturing   

Project "NEOFIBRIN" data sheet

The following table provides information about the project.

Coordinator
HISTOCELL SL 

Organization address
address: PARQUE TECNOLOGICO DE BIZKAIA EDIFICIO 801 PISO 2
city: DERIO BIZKAIA
postcode: 48160
website: www.histocell.com

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Project website http://www.histocell.com/index.php/en/r-d/current-projects/138-neofibrin
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.2.1.5. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Advanced manufacturing and processing)
2. H2020-EU.2.1.3. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Advanced materials)
3. H2020-EU.2.3.1. (Mainstreaming SME support, especially through a dedicated instrument)
4. H2020-EU.2.1.2. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Nanotechnologies)
 Code Call H2020-SMEINST-1-2016-2017
 Funding Scheme SME-1
 Starting year 2017
 Duration (year-month-day) from 2017-02-01   to  2017-07-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    HISTOCELL SL ES (DERIO BIZKAIA) coordinator 50˙000.00

Map

 Project objective

The main objective of NEOFIBRIN is to undertake a technical, industrialization and market feasibility study on an innovative regenerative medicine treatment for masticatory oral mucosa injuries based on a new advanced material, HR018-Neofibrin. The use of this material to develop a tridimensional natural scaffold for restoring masticatory oral mucosa functional activity is expected to significantly increase treatment efficiency over currently marketed products and to provide an alternative to allogenic and autologous grafts to treat localized mucosal damage. The application of Tissue Engineering techniques in clinical dentistry has several well-known problems, key among them the generation of a supportive biomaterial with regenerative capacity without the loss of consistency. Our novel biomaterial HR018-Neofibrin was developed combining natural materials and an exclusive design to promote the progressive formation and maturation of new epithelium while maintaining structural properties. Fibrin, one of the proteins involved in wound healing, provides a temporary extracellular matrix that facilitates cell migration, invasion and proliferation. Agarose, a polysaccharide from seaweed, gives the mechanical properties that enable surgical suturing and open healing. Histocell, a SME specialized in human regenerative medicine, has obtained licensing rights to the production of fibrin-agarose based artificial tissues and scaffolds for regeneration of tissues and oral mucosa. Successful completion of Phase 1 of NEOFIBRIN will yield a robust business plan for a much larger project that will seek funding under Phase 2 of the SEM Instrument, when the company will adapt a new facility for advanced manufacturing of innovative medical devices for the production of the new biomaterial HR018-Neofibrin and undertake clinical studies to obtain CE Mark for the product. Successful accomplishment of Phases 1 and 2 will be essential for accelerating the growth of the SME Histocell.

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The information about "NEOFIBRIN" are provided by the European Opendata Portal: CORDIS opendata.

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