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CellFoam

A novel tissue remodelling biomaterial to offer a revolutionary solution for treating Urinary Incontinence in dogs

Total Cost €

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EC-Contrib. €

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Partnership

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Project "CellFoam" data sheet

The following table provides information about the project.

Coordinator
BIO-CHANGE LTD 

Organization address
address: KIBUTZ NAHSHOLIM
city: KIBUTZ NAHSHOLIM
postcode: 30815
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Israel [IL]
 Project website http://www.biochange.life
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.2.1.5. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Advanced manufacturing and processing)
2. H2020-EU.2.1.3. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Advanced materials)
3. H2020-EU.2.3.1. (Mainstreaming SME support, especially through a dedicated instrument)
4. H2020-EU.2.1.2. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Nanotechnologies)
 Code Call H2020-SMEINST-1-2016-2017
 Funding Scheme SME-1
 Starting year 2017
 Duration (year-month-day) from 2017-03-01   to  2017-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    BIO-CHANGE LTD IL (KIBUTZ NAHSHOLIM) coordinator 50˙000.00

Map

 Project objective

Injectable bulking agents have been attempted to treat and manage stress urinary incontinence since the 1990's. But their application has been limited by efficacy, durability, biocompatibility, usability and other issues. Lack of a single, reproducible response from one agent has led to the adoption of several such materials. However, none of those materials can be used as a scaffold for tissue regeneration, they are mostly temporary tissue fillers. Once they degrade, the effectivity is diminished, typically within 6-8 months only. A permanent bulking agent was not successful as it often causes immunological adverse events (such as foreign body granulomas) that limit safety and efficacy. Between 1995-2011 a bovine crosslinked collagen product – Contigen® was used successfully to treat PMSI in dogs, however its production was stopped in 2011. CellFoam™ is a biomaterial scaffold augmentation agent that stimulates the body own cells to build de-novo tissue in place of the biomaterial. Thus, when degraded, a long-term tissue augmentation effect is maintained by urethral remodelling. As such continence is resolved. The overarching objective of the present feasibility study is to mitigate risks related to subsequent phases of the CellFoam™ innovation project, i.e. the risks associated with the planned industrialization, the commercialization of the solution and post-project exploitation of the results.

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The information about "CELLFOAM" are provided by the European Opendata Portal: CORDIS opendata.

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