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SeCtOR ENABleRs SIGNED

Standard Collagenous ORgans-on-chip ENvisaging Advanced Biological Researches

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 SeCtOR ENABleRs project word cloud

Explore the words cloud of the SeCtOR ENABleRs project. It provides you a very rough idea of what is the project "SeCtOR ENABleRs" about.

motivations    convenient    neuronal    experiences    scientific    skills    environment    compatible    kit    huge    device    natural    standardized    flexible    innovation    chip    imaging    plan    formulations    organs    community    economically    vascularized    complexity    laboratories    customizable    guarantee    sector    hoc    microfluidic    clinical    stem    culture    academics    effort    multidisciplinary    obtain    trials    establishing    bone    components    composition    3d    unconventional    live    cell    crosslinking    techniques    standardization    thermoplastic    complementary    industrial    biomimetic    envisage    integration    commercially    accessibility    convinced    controller    obtaining    designed    cells    microfluidics    potentialities    outcomes    medicine    perspective    approaching    areforeseeable    full    demonstrated    sme    collagenous    models    biology    represented    enablers    platform    toxicology    routine    diffusion    disruptive    mechanical    thermo    strategy    flexibility    ad    view    breakthroughs    personalized    risky   

Project "SeCtOR ENABleRs" data sheet

The following table provides information about the project.

Coordinator
CHERRY BIOTECH 

Organization address
address: 6 RUE GURVAND
city: RENNES
postcode: 35000
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 185˙076 €
 EC max contribution 185˙076 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2016
 Funding Scheme MSCA-IF-EF-SE
 Starting year 2017
 Duration (year-month-day) from 2017-09-01   to  2019-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CHERRY BIOTECH FR (RENNES) coordinator 185˙076.00

Map

 Project objective

SeCtOR ENABleRs aims to develop a convenient kit for the production of partially customizable organs-on-chip. The main motivations that lead us to get involved in this effort are to provide the scientific community of an easy-to-use, economically convenient and standardized microfluidic platform. This is expected to facilitate and promote the diffusion of advanced 3D cell culture systems in routine analyses and make results obtained from different experiences/laboratories more comparable. In this view we envisage possible applications in the field of stem cell biology, personalized medicine, toxicology as well as advanced pre-clinical trials. The kit main components are an ad hoc designed thermoplastic chip and a set of collagenous formulations. The chip design will allow the integration of a thermo-controller device compatible with live cell imaging techniques. A biomimetic approach and a cell-friendly crosslinking strategy will allow to control the composition and the mechanical properties of the collagenous formulations, thus approaching the complexity of natural cell environment. The flexibility of the kit will be demonstrated by obtaining vascularized neuronal and bone models using commercially available cells. Although some risky steps areforeseeable, the innovation in this project is more represented by the concept of organs on chip platform standardization than in significant disruptive breakthroughs. We are convinced that the accessibility to a convenient, standardized and flexible platform is the key to exploit the huge potentialities demonstrated by microfluidics organs on chip. The implementation of the proposed multidisciplinary work plan in an industrial environment will contribute to obtain unconventional complementary skills; understanding of the industrial perspective and needs and will finally guarantee the full exploitation of the project outcomes by establishing future SME/academics collaboration projects.

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