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SeCtOR ENABleRs SIGNED

Standard Collagenous ORgans-on-chip ENvisaging Advanced Biological Researches

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 SeCtOR ENABleRs project word cloud

Explore the words cloud of the SeCtOR ENABleRs project. It provides you a very rough idea of what is the project "SeCtOR ENABleRs" about.

enablers    community    experiences    hoc    establishing    thermo    convenient    ad    biology    breakthroughs    strategy    full    thermoplastic    formulations    compatible    cells    disruptive    laboratories    crosslinking    unconventional    culture    composition    obtaining    natural    sector    areforeseeable    3d    live    standardized    skills    trials    academics    approaching    kit    device    designed    customizable    multidisciplinary    demonstrated    routine    models    microfluidic    toxicology    chip    complexity    outcomes    huge    microfluidics    mechanical    risky    commercially    complementary    flexible    techniques    integration    collagenous    innovation    cell    personalized    motivations    organs    bone    components    imaging    effort    environment    accessibility    vascularized    guarantee    envisage    convinced    potentialities    obtain    industrial    plan    standardization    diffusion    medicine    represented    platform    sme    neuronal    clinical    flexibility    stem    economically    scientific    biomimetic    view    controller    perspective   

Project "SeCtOR ENABleRs" data sheet

The following table provides information about the project.

Coordinator
CHERRY BIOTECH 

Organization address
address: 6 RUE GURVAND
city: RENNES
postcode: 35000
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 185˙076 €
 EC max contribution 185˙076 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2016
 Funding Scheme MSCA-IF-EF-SE
 Starting year 2017
 Duration (year-month-day) from 2017-09-01   to  2019-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CHERRY BIOTECH FR (RENNES) coordinator 185˙076.00

Map

 Project objective

SeCtOR ENABleRs aims to develop a convenient kit for the production of partially customizable organs-on-chip. The main motivations that lead us to get involved in this effort are to provide the scientific community of an easy-to-use, economically convenient and standardized microfluidic platform. This is expected to facilitate and promote the diffusion of advanced 3D cell culture systems in routine analyses and make results obtained from different experiences/laboratories more comparable. In this view we envisage possible applications in the field of stem cell biology, personalized medicine, toxicology as well as advanced pre-clinical trials. The kit main components are an ad hoc designed thermoplastic chip and a set of collagenous formulations. The chip design will allow the integration of a thermo-controller device compatible with live cell imaging techniques. A biomimetic approach and a cell-friendly crosslinking strategy will allow to control the composition and the mechanical properties of the collagenous formulations, thus approaching the complexity of natural cell environment. The flexibility of the kit will be demonstrated by obtaining vascularized neuronal and bone models using commercially available cells. Although some risky steps areforeseeable, the innovation in this project is more represented by the concept of organs on chip platform standardization than in significant disruptive breakthroughs. We are convinced that the accessibility to a convenient, standardized and flexible platform is the key to exploit the huge potentialities demonstrated by microfluidics organs on chip. The implementation of the proposed multidisciplinary work plan in an industrial environment will contribute to obtain unconventional complementary skills; understanding of the industrial perspective and needs and will finally guarantee the full exploitation of the project outcomes by establishing future SME/academics collaboration projects.

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