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SeCtOR ENABleRs SIGNED

Standard Collagenous ORgans-on-chip ENvisaging Advanced Biological Researches

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 SeCtOR ENABleRs project word cloud

Explore the words cloud of the SeCtOR ENABleRs project. It provides you a very rough idea of what is the project "SeCtOR ENABleRs" about.

techniques    crosslinking    flexibility    kit    vascularized    customizable    flexible    designed    personalized    ad    standardization    environment    mechanical    perspective    standardized    outcomes    represented    thermoplastic    demonstrated    neuronal    huge    convinced    trials    controller    potentialities    skills    areforeseeable    biomimetic    enablers    accessibility    plan    sector    medicine    envisage    natural    unconventional    imaging    cell    motivations    formulations    routine    establishing    academics    chip    industrial    compatible    models    economically    effort    sme    thermo    scientific    microfluidic    complexity    cells    risky    full    experiences    laboratories    culture    breakthroughs    platform    diffusion    integration    device    components    innovation    microfluidics    live    approaching    complementary    clinical    multidisciplinary    hoc    view    obtain    disruptive    guarantee    composition    biology    commercially    convenient    community    3d    obtaining    organs    collagenous    stem    bone    toxicology    strategy   

Project "SeCtOR ENABleRs" data sheet

The following table provides information about the project.

Coordinator
CHERRY BIOTECH 

Organization address
address: 6 RUE GURVAND
city: RENNES
postcode: 35000
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 185˙076 €
 EC max contribution 185˙076 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2016
 Funding Scheme MSCA-IF-EF-SE
 Starting year 2017
 Duration (year-month-day) from 2017-09-01   to  2019-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CHERRY BIOTECH FR (RENNES) coordinator 185˙076.00

Map

 Project objective

SeCtOR ENABleRs aims to develop a convenient kit for the production of partially customizable organs-on-chip. The main motivations that lead us to get involved in this effort are to provide the scientific community of an easy-to-use, economically convenient and standardized microfluidic platform. This is expected to facilitate and promote the diffusion of advanced 3D cell culture systems in routine analyses and make results obtained from different experiences/laboratories more comparable. In this view we envisage possible applications in the field of stem cell biology, personalized medicine, toxicology as well as advanced pre-clinical trials. The kit main components are an ad hoc designed thermoplastic chip and a set of collagenous formulations. The chip design will allow the integration of a thermo-controller device compatible with live cell imaging techniques. A biomimetic approach and a cell-friendly crosslinking strategy will allow to control the composition and the mechanical properties of the collagenous formulations, thus approaching the complexity of natural cell environment. The flexibility of the kit will be demonstrated by obtaining vascularized neuronal and bone models using commercially available cells. Although some risky steps areforeseeable, the innovation in this project is more represented by the concept of organs on chip platform standardization than in significant disruptive breakthroughs. We are convinced that the accessibility to a convenient, standardized and flexible platform is the key to exploit the huge potentialities demonstrated by microfluidics organs on chip. The implementation of the proposed multidisciplinary work plan in an industrial environment will contribute to obtain unconventional complementary skills; understanding of the industrial perspective and needs and will finally guarantee the full exploitation of the project outcomes by establishing future SME/academics collaboration projects.

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