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ORBIS SIGNED

Open Research Biopharmaceutical Internships Support

Total Cost €

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EC-Contrib. €

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Partnership

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ORBIS project word cloud

Explore the words cloud of the ORBIS project. It provides you a very rough idea of what is the project "ORBIS" about.

formulations dissolution ukraine preclinical lengthy international material finland inefficient physical 70 attrition demanded scientists links republic affordable amalgamate chemistry czech career industry gap skills internships pharmacy drug actives pharmaceutical approximately fill synthesis germany integrate technologies proposes computations biopharmaceutical poland biopharmaceutics public accessible market 20 inter membrane experts solubility environment consolidate stage permeability poor create cooperation bioanalysis expertise form rate multidisciplinary stimulating nanotechnology science soft outcomes enters action concentrating classification oral network individual country exchange productivity candidates class academic bioavailability complementary pharmacology bioanalytical sectoral overarching orbis medicine beneficiaries secondments dermal drugs society industrial medicines molecules academia ireland

Project "ORBIS" data sheet

The following table provides information about the project.

Coordinator	UNIWERSYTET MEDYCZNY IM KAROLA MARCINKOWSKIEGO W POZNANIU Organization address address: UL. FREDRY 10 city: POZNAN postcode: 61-701 website: www.ump.edu.pl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Poland [PL]
Total cost	2˙268˙000 €
EC max contribution	2˙268˙000 € (100%)
Programme	1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
Code Call	H2020-MSCA-RISE-2017
Funding Scheme	MSCA-RISE
Starting year	2018
Duration (year-month-day)	from 2018-03-01 to 2022-02-28

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	UNIWERSYTET MEDYCZNY IM KAROLA MARCINKOWSKIEGO W POZNANIU UNIWERSYTET MEDYCZNY IM KAROLA MARCINKOWSKIEGO W POZNANIU Organization address address: UL. FREDRY 10 city: POZNAN postcode: 61-701 website: www.ump.edu.pl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	PL (POZNAN)	coordinator	684˙000.00
2	POLITECHNIKA POZNANSKA POLITECHNIKA POZNANSKA Organization address address: PL MARII SKLODOWSKIEJ CURIE 5 city: POZNAN postcode: 60 965 website: www.put.poznan.pl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	PL (POZNAN)	participant	369˙000.00
3	JOINT STOCK COMPANY FARMAK JOINT STOCK COMPANY FARMAK Organization address address: 63, FRUNZE STR. city: KIJEV postcode: 4080 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UA (KIJEV)	participant	315˙000.00
4	SIEC BADAWCZA LUKASIEWICZ - INSTYTUT FARMACEUTYCZNY SIEC BADAWCZA LUKASIEWICZ - INSTYTUT FARMACEUTYCZNY Organization address address: UL. RYDYGIERA 8 city: WARSZAWA postcode: 01 793 website: www.ifarm.eu contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	PL (WARSZAWA)	participant	274˙500.00
5	ZENTIVA, K.S. ZENTIVA, K.S. Organization address address: U KABELOVNY 130 city: Prague postcode: 10237 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CZ (Prague)	participant	270˙000.00
6	HELSINGIN YLIOPISTO HELSINGIN YLIOPISTO Organization address address: YLIOPISTONKATU 3 city: HELSINGIN YLIOPISTO postcode: 14 website: www.helsinki.fi contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FI (HELSINGIN YLIOPISTO)	participant	171˙000.00
7	THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN Organization address address: College Green city: DUBLIN postcode: 2 website: www.tcd.ie contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IE (DUBLIN)	participant	112˙500.00
8	PHYSIOLUTION GMBH PHYSIOLUTION GMBH Organization address address: WALTHER-RATHENAU-STRASSE 49 A city: GREIFSWALD postcode: 17489 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (GREIFSWALD)	participant	45˙000.00
9	APPLIED PROCESS COMPANY LIMITED APPLIED PROCESS COMPANY LIMITED Organization address address: BUILDING 11 CHERRYWOOD BUSINESS PARK LOUGHLINSTOWN city: DUBLIN postcode: D18DH50 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IE (DUBLIN)	participant	27˙000.00
10	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY Organization address address: RUTGERS PLAZA 3 city: NEW BRUNSWICK postcode: 8901 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	US (NEW BRUNSWICK)	partner	0.00

Map

Project objective

The current process of drug development is lengthy and inefficient. Only 1 out of approximately 10,000 drug molecules enters the market. Therefore more effective medicines, demanded by society, cannot be provided by pharmaceutical industry. To fill this gap, Open Research Biopharmaceutical Internships Support (ORBIS) proposes that the high attrition rate of new drug candidates might be reduced by over 20% by improving early stage R&D productivity. The overarching objective of ORBIS is therefore to form an international and inter-sectoral academic and industrial network. The action is aimed at improving the preclinical pathway of medicine development concentrating on processes and technologies. The goal is to integrate multidisciplinary research by involving academia and industry from EU (Poland, Ireland, Finland, Germany and Czech Republic), EU associated country (Ukraine) and US to address the poor drug bioavailability as 70% of actives have solubility and/or membrane permeability problems. The action is addressed at selected molecules of class II and IV of Biopharmaceutics Classification System, to improve their pharmaceutical potential. The complementary consortium comprises experts in computations, physical chemistry, material science, nanotechnology, pharmacy, pharmacology and bioanalysis. The secondments will create a stimulating environment for early stage researchers to advance their individual career and soft skills. EU scientists will amalgamate their expertise in drug synthesis and dissolution, oral formulations, and bioanalytical methods with the knowledge on dermal research provided by the US partner. ORBIS will consolidate the existing links, promote long-term cooperation and exchange of knowledge between beneficiaries and partners. ORBIS will also enhance dissemination of new research outcomes and raise the awareness among the general public of the importance of drug delivery research that makes new drugs more accessible and affordable for society.

Deliverables

List of deliverables.
Mid-term meeting.	Other	2020-01-14 15:07:29
Workshop on dosage forms and drug delivery systems.	Other	2019-10-15 13:13:56
2nd School on oral dosage and drug delivery systems.	Other	2019-10-15 13:14:08
1st School on pharmaceutical preformulation testing of APIs and dosage forms.	Other	2019-10-15 12:11:42
Open Workshop on process development of drug substances.	Other	2019-10-15 12:11:42
Kick-off meeting.	Other	2019-10-15 12:11:42
ORBIS website launched + Social media channels established.	Websites, patent fillings, videos etc.	2019-10-15 12:11:42

Take a look to the deliverables list in detail: detailed list of ORBIS deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2019	Piotr J. Rudzki, PrzemysÅ‚aw Biecek, MichaÅ‚ Kaza Incurred Sample Reanalysis: Time to Change the Sample Size Calculation? published pages: , ISSN: 1550-7416, DOI: 10.1208/s12248-019-0293-2	The AAPS Journal 21/2	2019-10-15

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The information about "ORBIS" are provided by the European Opendata Portal: CORDIS opendata.

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