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ORBIS SIGNED

Open Research Biopharmaceutical Internships Support

Total Cost €

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EC-Contrib. €

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Partnership

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 ORBIS project word cloud

Explore the words cloud of the ORBIS project. It provides you a very rough idea of what is the project "ORBIS" about.

bioanalysis    industry    ukraine    bioavailability    links    rate    overarching    poland    form    secondments    biopharmaceutics    action    nanotechnology    chemistry    membrane    academia    beneficiaries    scientists    internships    stage    consolidate    soft    society    fill    academic    medicine    approximately    public    dissolution    concentrating    inefficient    medicines    material    market    network    science    computations    70    preclinical    permeability    amalgamate    expertise    dermal    exchange    cooperation    accessible    enters    pharmaceutical    biopharmaceutical    molecules    orbis    multidisciplinary    affordable    drug    classification    stimulating    integrate    finland    class    candidates    gap    career    synthesis    inter    republic    oral    bioanalytical    solubility    productivity    lengthy    pharmacology    ireland    attrition    industrial    complementary    poor    physical    international    formulations    individual    experts    technologies    environment    create    pharmacy    actives    country    sectoral    proposes    20    germany    outcomes    czech    drugs    demanded    skills   

Project "ORBIS" data sheet

The following table provides information about the project.

Coordinator
UNIWERSYTET MEDYCZNY IM KAROLA MARCINKOWSKIEGO W POZNANIU 

Organization address
address: UL. FREDRY 10
city: POZNAN
postcode: 61-701
website: www.ump.edu.pl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Poland [PL]
 Total cost 2˙268˙000 €
 EC max contribution 2˙268˙000 € (100%)
 Programme 1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
 Code Call H2020-MSCA-RISE-2017
 Funding Scheme MSCA-RISE
 Starting year 2018
 Duration (year-month-day) from 2018-03-01   to  2022-02-28

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIWERSYTET MEDYCZNY IM KAROLA MARCINKOWSKIEGO W POZNANIU PL (POZNAN) coordinator 684˙000.00
2    POLITECHNIKA POZNANSKA PL (POZNAN) participant 369˙000.00
3    JOINT STOCK COMPANY FARMAK UA (KIJEV) participant 315˙000.00
4    SIEC BADAWCZA LUKASIEWICZ - INSTYTUT FARMACEUTYCZNY PL (WARSZAWA) participant 274˙500.00
5    ZENTIVA, K.S. CZ (Prague) participant 270˙000.00
6    HELSINGIN YLIOPISTO FI (HELSINGIN YLIOPISTO) participant 171˙000.00
7    THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN IE (DUBLIN) participant 112˙500.00
8    PHYSIOLUTION GMBH DE (GREIFSWALD) participant 45˙000.00
9    APPLIED PROCESS COMPANY LIMITED IE (DUBLIN) participant 27˙000.00
10    RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY US (NEW BRUNSWICK) partner 0.00

Map

 Project objective

The current process of drug development is lengthy and inefficient. Only 1 out of approximately 10,000 drug molecules enters the market. Therefore more effective medicines, demanded by society, cannot be provided by pharmaceutical industry. To fill this gap, Open Research Biopharmaceutical Internships Support (ORBIS) proposes that the high attrition rate of new drug candidates might be reduced by over 20% by improving early stage R&D productivity. The overarching objective of ORBIS is therefore to form an international and inter-sectoral academic and industrial network. The action is aimed at improving the preclinical pathway of medicine development concentrating on processes and technologies. The goal is to integrate multidisciplinary research by involving academia and industry from EU (Poland, Ireland, Finland, Germany and Czech Republic), EU associated country (Ukraine) and US to address the poor drug bioavailability as 70% of actives have solubility and/or membrane permeability problems. The action is addressed at selected molecules of class II and IV of Biopharmaceutics Classification System, to improve their pharmaceutical potential. The complementary consortium comprises experts in computations, physical chemistry, material science, nanotechnology, pharmacy, pharmacology and bioanalysis. The secondments will create a stimulating environment for early stage researchers to advance their individual career and soft skills. EU scientists will amalgamate their expertise in drug synthesis and dissolution, oral formulations, and bioanalytical methods with the knowledge on dermal research provided by the US partner. ORBIS will consolidate the existing links, promote long-term cooperation and exchange of knowledge between beneficiaries and partners. ORBIS will also enhance dissemination of new research outcomes and raise the awareness among the general public of the importance of drug delivery research that makes new drugs more accessible and affordable for society.

 Deliverables

List of deliverables.
Mid-term meeting. Other 2020-01-14 15:07:29
Workshop on dosage forms and drug delivery systems. Other 2019-10-15 13:13:56
2nd School on oral dosage and drug delivery systems. Other 2019-10-15 13:14:08
1st School on pharmaceutical preformulation testing of APIs and dosage forms. Other 2019-10-15 12:11:42
Open Workshop on process development of drug substances. Other 2019-10-15 12:11:42
Kick-off meeting. Other 2019-10-15 12:11:42
ORBIS website launched + Social media channels established. Websites, patent fillings, videos etc. 2019-10-15 12:11:42

Take a look to the deliverables list in detail:  detailed list of ORBIS deliverables.

 Publications

year authors and title journal last update
List of publications.
2019 Piotr J. Rudzki, Przemysław Biecek, Michał Kaza
Incurred Sample Reanalysis: Time to Change the Sample Size Calculation?
published pages: , ISSN: 1550-7416, DOI: 10.1208/s12248-019-0293-2
The AAPS Journal 21/2 2019-10-15

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The information about "ORBIS" are provided by the European Opendata Portal: CORDIS opendata.

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