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NanoBioMap SIGNED

Nanoparticle Biointerface Mapping

Total Cost €

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EC-Contrib. €

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Partnership

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 NanoBioMap project word cloud

Explore the words cloud of the NanoBioMap project. It provides you a very rough idea of what is the project "NanoBioMap" about.

professor    flows    characterization    pollutants    complementary    antibody    group    skills    biointerface    modification    multiple    involve    versatile    acquisition    tracking    3d    quantum    library    particles    nanobiomap    transferable    researcher    dots    spatial    environments    tailor    24    training    prospects    career    catalysis    combining    dublin    synthesis    analyzing    nanomaterial    image    media    biomolecules    nanosized    dimension    water    dawson    packages    biology    kenneth    adding    uses    maps    science    nanoparticles    made    envision    interaction    obtain    mapping    interdisciplinary    biological    expanding    bionano    extensive    objects    enzymatic    map    cell    months    ing    electron    elemental    treatment    interactions    ray    epitopes    edge    college    builds    independent    surface    receptors    tagged    tool    vaccine    cutting    13    microscopy    university    reconstruction    cancer    reached    corona    me    nanoparticle    protein    coronas   

Project "NanoBioMap" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN 

Organization address
address: BELFIELD
city: DUBLIN
postcode: 4
website: www.ucd.ie

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Ireland [IE]
 Total cost 175˙866 €
 EC max contribution 175˙866 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2016
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-10-01   to  2020-09-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN IE (DUBLIN) coordinator 175˙866.00

Map

 Project objective

The Nanoparticle Biointerface Mapping project builds on the extensive bionano interactions research in the group of Professor Kenneth Dawson at University College Dublin. In the NanoBioMap project I propose a cutting-edge interdisciplinary approach to develop a versatile tool allowing me to obtain detailed 3D maps of biomolecules at the surface of nanoparticles in complex biological media and study their importance for cell interactions. I will build on my extensive knowledge of nanomaterial science to develop this 3D mapping tool combining a tailor-made library of antibody-tagged quantum dots with electron microscopy 3D image reconstruction and X-ray elemental mapping. The resulting versatile method has multiple uses far beyond analyzing protein coronas. I envision applications of this state-of-the-art mapping tool in areas such as vaccine development, enzymatic catalysis on supported particles, cancer treatment and tracking of pollutants in water flows. The proposed project has 4 objective which will be reached over 24 months, within 13 work packages, including training-through-research and acquisition of transferable and complementary skills, contributing to the advancement of my career beyond this project, as a future independent researcher. The main objective is developing a tool to allow 3D mapping of protein epitopes at the surface of nanosized objects, with applications far beyond my test systems. The other objectives involve testing my tool to map epitopes in the protein corona at nanoparticles and study their interaction with cell receptors, focusing on spatial distribution of specific receptors. The proposal builds on my current extensive knowledge of nanomaterial synthesis, surface modification and characterization in complex environments adding a cell biology dimension, thus expanding my knowledge and career prospects.

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The information about "NANOBIOMAP" are provided by the European Opendata Portal: CORDIS opendata.

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